Research Medewerkers

Fijs van Leeuwen (Head of IMI-Lab)

• Development of new (targeted) imaging agents for molecular imaging applications (chemistry)
• Exploring the (clinical) potential of multimodal imaging agents
• Fluorescence- and radioguided surgery
• Diagnostic and surgical identification of diseased tissue

Renato Valdés Olmos

• Clinical development and application of hybrid cameras for radioactive/fluorescence signal detection
• Development and application of 3D augmented - and mixed reality models in surgical navigation
• Dedicated molecular breast imaging & radioguided intervention

Aldrik Velders (Head of BioNT group, Wageningen University)

• Development of supramolecular sensor strategies
• Exploitation of nanoparticle properties for optical sensing
• Nuclear Magnetic Resonance (NMR) and fluorescence spectroscopy
• Microfluidics for on-flow spectroscopic sensing devices

Tessa Buckle

• Generation animal models for imaging studies
• Preclinical in vivo imaging using multiple modalities
• Microsurgery
• Visualization of nerve bundles

Mick Welling

• Biological validation and testing of probes and tracers: peptides, proteins, (stem) cells
• Molecular imaging and analysis based on radioactivity (pharmacology and targeting) in experimental animal models
• Bacterial imaging
• Molecular monitoring of antimicrobial therapy

Anton Bunschoten

• Multimodal imaging based on fluorescence and radioactivity
• Non-covalent interactions on proteins
• Förster resonance energy transfer
• Bacterial imaging

Frits Smit

• Nuclear Medicine

Daphne Rietbergen (Head of Nuclear Medicine)

• Nuclear Medicine e.g. Tracer administration, lymphoscintigraphy, SPECT/CT, radionuclear therapy, radioguided surgery
• Clinical implementation of innovating surgical guidance techniques: Fluorescence- and radioguided surgery, intraoperative image navigation

Matthias van Oosterom

• Applied Physics
• Prototyping
• Fluorescence and Bioluminescence
• Surgical Navigation

Silvia Spa

• Functionalization of bionanoparticles
• Self-assembly processes
• Development of imaging agent for nerve visualization
• u-contact printing

Pip Meershoek

• Clinical implementation of navigated ultrasound

Clarize de Korne

• Cell culture
• Immunohistochemical and fluorescent staining
• (Confocal) microscopy

Beatrice M.F. Winkel

• Nuclear medicine
• Medical (molecular) Imaging
• Translational research
• Parasitology
• Malaria and other skin penetrating parasites

Jan Bart ten Hove

• Synthesis and surface modification of nanoparticles
• (Orthogonal) chemistry
• Biosensor development
• Transmission Electron Microscopy (TEM)
• Diffusion Ordered Spectroscopy

Danny van Willigen

• Synthesis of fluorescent dyes
• Synthesis of (hybrid) imaging agents
• Labeling of biomolecules for imaging applications

Fabian Hensbergen

• Synthesis of fluorescent dyes

Sven van Leeuwen

• Phantom production
• Hardware experiments
• Hardware maintenance

Diego Staphorst

• Development of computer assisted motility tracking software

Luuk Lageschaar

• micro-contact printing
• cell and protein labeling
• confocal microscopy

Michael Boutkan

• Nerve targeting
• Tracer synthesis

Germaine Aalderink

• Nerve targeting
• In vitro studies

Dr. Luis J. Cruz, head of TNI (Assistant Professor)

• Nanomedicine
• Molecular Imaging
• Drug delivery systems
• Immunotherapy
• Nanotherapeutics
• Smart nanobiomaterials
• Photodynamic therapy
• NanoRegenerative Medicine

Dr. Eric L. Kaijzel (Assistant Professor)

• Nanomedicine
• Imaging
• Immunotherapy
• Nanotherapeutics
• Smart nanobiomaterials
• GCP/GRP

Prof. Dr. Mathias H.H.D. Hoehn (Visiting Professor)

• Regenerative medicine
• Cerebral ischemia
• Immunotherapy
• Stem cells
• Molecular imaging
• In vivo MRI and optical imaging

Dr. Gastón Fuentes Estévez (Senior researcher)

• Drug delivery systems
• Calcium phosphates ceramics synthesis
• Calcium phosphates cements
• Calcium phosphates composites
• Statistics applied to biomaterials

Dr. Raimundo Fernandes de Araújo Júnior (Assistant Professor)

• Immunohistochemistry
• Immunoflourescence
• Flow cytometry
• Western blot

Dr. Yuedan Li (Postdoctoral fellow)

• biochemical, cell-based, or immunological assays
• stem cell therapies for genetic disorders
• molecular imaging

Dr. Christina Eich (Postdoctoral Researcher)

• Tumour Immunology, Immunology, Immunotherapy
• Molecular Biology
• (Molecular) Imaging
• Hematopoietic stem cells
• Transcription Factors
• Immunotherapy

Dr. Mara Saccomano (Postdoctoral Researcher)

Drs. Marieke A. Stammes (PhD-student)

• (Molecular) Multimodal Imaging
• Preclinical Experiments
• Radioactivity Based Analysis

Drs. C. da Silva (Researcher, PhD-candidate, Immunologist (io; smbwo))

• Oncology
• Immunology
• Tumor Immunology
• Immunotherapy
• (Immunogenic) Chemotherapy
• Nanomedicine (PLGA nanoparticles)
• Tumor microenvironment immune modulation
• Therapeutic cancer vaccines

Drs. Ruben Huis in ’t Veld (PhD Student)

• Oncology
• Immunology
• Photodynamic therapy
• Nanomedicine

Drs. Luana Zerrillo (PhD Student)

• Nanoparticles
• Drug delivery
• Molecular imaging
• Nanomedicine

Drs. Chih Kit Chung (PhD Student)

• Immunology
• Tumor immunology
• Immunotherapy
• Nanomedicine (nanoparticles)

Drs. Jomarien Garcia (PhD Student)

• Polymeric biomaterials
• Nanomedicine
• Tissue enginnering
• Cartilage regeneration

Drs. Yaima Campos Mora (PhD Student)

• Scaffolds
• Tissue engineering
• Cartilage regeneration

Mehrman Chalaki, BSc (MSc Student)

Drs. Ana Luiza Oliviera (PhD student)

• Molecular biology of cancer
• Cell culture
• Flow cytometry
• Immunofluorescence

Drs. Olena Vepris (Researcher)

Ivo Que (Senior Research Technician)

• Role imaging equipment
• Role animal facility (trainer/ambassador) etc

Tracy Li (Research Technician)

• Cell culture
• Imaging
• Animal works

Drs. Fabio Baldazzi (Research Technician)

• Molecular Biology
• Analytical Chemistry
• Cell culture

Dr. Monique Reijnierse

• Musculoskeletal
• Ultrasound

Prof.dr.ir. Boudewijn P.F. Lelieveldt (Professor)

• Integration of a-priori knowledge into segmentation and registration algorithms
• Data analytics for 3D omics data
• Main applications: neuroimaging and multi-modal pre-clinical imaging

Dr. Ir. Rob J. van der Geest (Associate professor)

Dr. ir. Jouke Dijkstra (Associate professor)

• IntraVascular Ultrasound (IVUS).
• Optical Coherence Tomography (OCT).
• Vascular image analysis (Computed Tomography Angiography).
• Analysis, registration and visualization of multi-model molecular images.
• Image guided surgery.

Dr. Berend C. Stoel (Associate professor)

• Image Processing in Pulmonology, Orthopaedics, Rheumatology and Ophthalmology
• Technical and Clinical Validation of Image Processing
• Quality Control and Standardization in Quantitative Computed Tomography
• Applications of Image Processing in Drug Evaluation Trials

Dr. ir. Marius Staring (Associate professor)

• biomedical machine learning
• medical image registration
• medical image analysis
• radiotherapy
• dedicated to high quality and open source software implementations

Drs. Evgeni Aizenberg (PhD Student)

• Image Processing
• Computer-aided diagnosis of disease

Dr. M. Els Bakker (Senior researcher)

• Pulmonary image processing
• Validation of developed pulmonary sofware
• Financial project management
• Works council

Dr.ir. Alexander Broersen (scientific researcher)

• Research interests include the detection, classification, and quantification of coronary vessels by combining analyses from intravascular ultrasound and computed tomography angiography.

Drs. Niels Dekker (Scientific programmer)

• Intravascular image analysis
• Advanced programming techniques
• C++, Qt, MFC, MeVisLab, DICOM

Dr. Oleh Dzyubachyk (post-doctoral researcher)

• Mathematical methods for image processing
• Whole-body MR imaging
• Cell segmentation and tracking

Dr. Jeroen Eggermont (Scientific Researcher)

• Current research interests are:
• Intravascular Ultrasound (IVUS)
• Optical Coherence Tomography (OCT)).
• Atherosclerotic Plaque Characterization
• Natural Computing
• Optimization
• Data Mining

Ir Michèle Huijberts (IT-Project manager)

Ir. Pieter Kitslaar (Scientific programmer)

• Vascular image analysis and quantification
• Quantitative coronary CT angiography
• Vessel tree segmentation

Ir. Patrick de Koning (Scientific researcher)

• Development of Image Analysis Techniques for Time-Resolved 3-Dimensional, 3-Directional MR Velocity Mapping.
• Automated evaluation of vascular MR image data.

Drs. Baldur van Lew (Scientific Programmer)

• Visualization of brain images
• Network analysis

Drs. Ahmed Mahfouz (Postdoctoral Researcher)

• Imaging genetics
• Bioinformatics
• Spatio-temporal gene expression
• Biological Network analysis

Prof. Dr. Ir. J.H.C. Reiber (Professor)

• (Knowledge guided) image processing and its clinical applications

Drs. Denis Shamonin (Scientific programmer)

• Pulmonary image processing and quantification
• Visualization and analysis algorithms for clinical applications

Drs. Hessam Sokooti (PhD Student)

• Image Registration
• Machine Learning
• Biomedical Image Processing
• Biomedical Signal Processing

Drs. Zhuo Sun (PhD Student)

• Alzheimer’s disease and aging progress model
• Atlas selection strategy in the atlas base analysis methods
• Alzheimer’s disease classification and biomarker selection

Dr. Qian Tao ( )

• Analysis of clinical MR images
• Multi-modality image registration and intraoperative image integration
• Risk stratification, machine learning

Drs. Leo Wolf (Software manager)

• Software ontwikkeling, zowel methodologisch als praktisch: Agile methoden en technieken tezamen met uitbreidingen op programmeertalen zoals support voor functioneel programmeren
• Web ontwikkeling
• Theoretische onderwerpen als correctheid van algoritmen
• Sinds enkele jaren QA manager

Drs. Zhiwei Zhai (PhD student)

• pulmonary image analysis,
• Pulmonary biomarker design.

Drs C. Zhang (PhD Student)

• Compressed Sensing based MRI
• Comparative Visualization

Drs. Qing Cao (PhD student)

• Automatic Coronary Artery Analysis from computed tomography angiography

Drs. Mohamed Elmahdy (PhD student)

• Biomedical Image Analysis
• Deep Learning
• Medical Image Registration
• Biomedical Signal Processing
• Computer Vision

Dr. Thomas Kroes (Researcher)

• Computer graphics and visualization
• Tool development for large-scale image processing infrastructures

Dr. Mohamed Kilany Hassan (Post-doctoral Researcher)

• Biomedical Image Processing
• Machine Learning
• Photoacoustic Imaging
• Brain Stimulation Modeling
• Low-Intensity Focused Ultrasound (LIFU)