Beatrice M.F. Winkel

Area(s) of interest

  • Nuclear medicine
  • Medical (molecular) Imaging
  • Translational research
  • Parasitology
  • Malaria and other skin penetrating parasites


Beatrice studied both Medicine as well as Biomedical Sciences at the LUMC. During her Biomedical Sciences Master she became interested in molecular imaging and both her research internships were in this field. (Hematopoietic Stem Cell imaging in the bone marrow environment and nuclear navigation technologies in the context of sentinel node surgery)

Beatrice started her PhD in 2014 in the field of Malaria research. She studies the skin phase of malaria infection when sporozoites, motile malaria parasites, are injected into the skin by mosquito bite. Using fluorescence molecular imaging techniques malaria and other skin penetrating parasites can be targeted and the kinetics and motility of these parasites in human skin can be investigated.

Recent publications

Nombela-Arrieta, C., Pivarnik, G., Winkel, B., Canty, K.J., Harley B., Mahoney, J.E., Park, S.-Y., Lu, J., Protopopov, A., Silberstein, L.E., Quantative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment, Nature Cell Biology,2013, 15 (5), 533-553

B. Winkel, J. Kuil, D. Rietbergen, R. Valdes-Olmos, F. van Leeuwen. Combining radioactivity with fluorescence: the first clinical experiences using hybrid tracer NederlandsTijdschrift voor Nucleaire Geneeskunde, 2013

T. Engelen, B. Winkel, D. Rietbergen, G. Kleinjan, S. Vidal-Sicart, N. van den Berg, R. Valdes-Olmos, F. van Leeuwen. The next evolution in radioguided surgery: Breast cancer related sentinel node localization using a freehandSPECT-mobile gamma camera combination. American Journal of Nuclear Medicine and Molecular Imaging, 2015



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The Netherlands