Dr. Luis J. Cruz, head of TNI

Assistant Professor


  • Nanomedicine
  • Molecular Imaging
  • Drug delivery systems
  • Immunotherapy
  • Nanotherapeutics
  • Smart nanobiomaterials
  • Photodynamic therapy
  • NanoRegenerative Medicine


Dr. Luis J. Cruz  graduated from the Havana University and was soon recruited by the prestigious Center for Genetic Engineering and Biotechnology in Cuba, where he earned his M.S. in Biotechnology for his work on therapeutic mimetic peptides, diagnostic assay systems and distinct vaccine candidates (such as HIV-1, HBV, HCV, prostatic cancer vaccine). During this time, he received two awards from the Cuban National Academy of Sciences. Dr. Cruz was also awarded a Spanish AECI fellowship at the Autonomous Barcelona University and he won a Cuban-Spanish collaboration grant for training in peptide vaccines at the Barcelona University. He later worked on peptides for cancer therapy (including Kahalalide F, which is currently in clinical trials) at the Biomedical Research Institute in Barcelona. By 2005 he received training at the PharmaMar S.A., Spain. Between 2005-2007 he did several training and working visits, including visits at the Center of Biological Investigations, Madrid, Spain and the Department of Pharmacological Chemistry and Toxicology, Chemical Sciences Institute, Chile University. His dedication to scientific research resulted in a PhD at the Barcelona University in 2006 with the highest honour (Excellent cum laude), under supervision of Profs. Albericio and Andreu. Dr. Cruz later moved to the Netherlands after earning a 004Darie Curie post-doctoral fellowship to work on the project Immunonamap (PI Prof.Figdor). He did his second post-doctoralat the Leiden University Medical Center (LUMC) on the CTMM project, on tracking of cancer vaccines in the human body, under the supervision of Profs. Ossendorp and Lowik. Dr. Cruz has authored and co-authored more than 100 scientific articles, 12 conference articles and 15 patents. He has co-supervised 4 PhD students, 4 Master student, 4 BSc students and 2 Postdocs. He was involved in several national and international projects such as the Marie Curie project Immunonamap and he is involved in other Marie Curie projects such as PRISAR, BrainPath, TargetCare and recently ISPIC. During the last years, Dr. Cruz was awarded with the prestigious NWO VIDI and LUMC fellowship personal grants, KNAW China Exchange Programme and two European Erasmus Plus Mobility grant between Leiden University Medical Center (LUMC), Havana University, and Havana Medical Sciences University in Cuba. He is a coordinater and promotor of the collaboration between LUMC and Latin American and Caribbean. Currently, he established his own research lines in the field of nanomedicine, immunology and medical imaging as a group leader of the Translational Nanobiomaterials and Imaging in the Radiology Department at the LUMC. Dr. Cruz’ multidisciplinary team and research at the LUMC is mainly focused on developing innovative therapeutic products with potential usefulness for clinical application. His multidisciplinary track record in the chemical and (bio) medical field, combined with his proven ability to bridge the gap between bench and bedside aids in the successful integration of synthetic nanochemical strategies with biomedical applications.



Leids Universitair Medisch Centrum
Gebouw 1
Kamer C02-187H

Albinusdreef 2
2333 ZA Leiden
Tel: +31 71 5265764

Postzone C2-S
Postbus 9600
2300 RC Leiden

E-mail: L.J.Cruz_Ricondo@lumc.nl