Tessa Buckle, PhD

Area(s) of interest

  • Generation animal models for imaging studies
  • Preclinical in vivo imaging using multiple modalities
  • Microsurgery
  • Visualization of nerve bundles


Tessa graduated in 2001 from HLO Zoology at the Hogeschool van Utrecht. After obtaining her bachelor degree, she started working at the Pharmacokinetics group of dr. Olaf van Tellingen at the Department of Clinical Chemistry within the Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital (NKI-AvL). Here, she developed tumor models for pharmacological studies using microsurgical techniques and generated a number of (luciferase positive) tumor models for therapy and drug efficacy studies. In 2008 she played an instrumental role in the initiation of the preclinical Mouse Cancer Clinic at the NKI-AvL, where she later became coordinator. In 2008 she started working at the Departments of Radiology and Nuclear Medicine within the NKI-AvL. Here she helped set up the molecular imaging group of dr. Fijs van Leeuwen. She gained extensive experience in bioluminescence, fluorescence, CT, ultrasound, SPECT, PET, and MR imaging, was involved in the developed of new (targeted) imaging probes, and has realized the clinical translation of a multimodal imaging agent for sentinel node biopsy. In 2011 she moved with the Interventional Molecular Imaging group to the Department of Radiology at the Leiden University Medical Center, where she obtained her PhD in October 2012. In her current function as senior postdoctoral researcher she continues to work in the field of imaging probe development and preclinical validation, whereby the primary focus lies with the clinical translation of these imaging probes. She is a visiting scientist at the division of molecular pathology at the NKI-AvL (group of Dr. Jos Jonkers) where she in involved in the use of (advanced) tumor models for imaging studies.



Leiden University Medical Center
Building 1
Room C2-204

Albinusdreef 2
2333 ZA Leiden
Tel: 715262042

Postalzone C2-S
P.O. Box 9600
2300 RC Leiden
The Netherlands

E-mail: t.buckle@lumc.nl