Het onderzoek

Development of a Clinical Diagnostic System for assessing Orthopaedic Implant Stability



  • Bart L. Kaptein, MSc, PhD
  • Eric H. Garling, PhD
  • PhD student
  • Bart. C.G.W. Pijls, MD


Model-based RSA

Start/End Date


Grant giver

Capital District Health Authority

Academic partners

  • Dalhousie University, Faculty of Medicine, Division of Orthopaedic Surgery, Halifax, Canada
  • Commercial partners
  • Halifax Biomedical Inc., Halifax, Canada
  • Medis specials b.v., Leiden, The Netherlands


A major issue in orthopaedic surgery is aseptic loosening of joint replacements. Several studies have indicated that early micromotion of the implant relative to the bone can predict future aseptic loosening and subsequent revision. Radiostereometric analysis, RSA, is the gold standard for measuring micromotion and is currently mainly used in scientific applications. The goal of the AIF-project is to explore and develop the clinical applicability of RSA in everyday orthopaedic practice.

An important aspect of this project is to further investigate migration patterns of prosthetic designs and to determine the differences between normal and abnormal micromotion. In order to complete the current knowledge regarding micromotion we also intend to study long term migration patterns and it's correlation to clinical parameters.