The LUMC is an innovative Transplant Center. As a center of expertise for kidney transplantations we have a lot of experience with complex problems.
In 1966 Leiden was the first place in the Netherlands where a kidney transplantation was performed. Since then more than four thousand kidney transplantations have been performed here. At the LUMC we perform about a hundred and twenty-five kidney transplantations per year and there are more than one thousand patients who come to us for check-ups after a transplantation. Our doctors are very experienced both when it comes to emergency transplantations (with kidneys of deceased donors) as well as transplantations involving living kidney donors.
We also specialize in exceptional situations, such as blood type incompatible transplantations or transplantations for people who have previously had a kidney transplantation. Our team of experts is ready to look together with you for the best possible treatment.
In 2016 the LUMC performed 126 kidney transplantations. We estimate that in 2017 we perform transplantations with kidneys from living donors for about 60% of the patients, before they have to start dialysis (pre-emptive). In comparison, in 2000 this percentage was 15% of the patients. This increase is the result of our cooperation with the referring centers and the efficiency of our donor and recipient procedures as regards registration, preparation, examination and operation planning.
Besides, there is a major decrease (60%) of acute rejection of the organ. This is because of improvement of medication and treatment strategies.
At the LUMC more than 550 liver transplantations have been performed with excellent results. We continuously work on further improvement of our programme. This includes improvement of the condition of the recipients before the operation, improvement of the transplantation itself -for instance with machine preservation of the donor liver-, and better aftercare -for instance fighting rejection by reducing side effects, and better treatment of biliary tract problems after transplantation. Specialists and specialist nurses ensure there is good communication with and support for the patient. Also optimum communication with referrers and other healthcare providers is one of our key priorities.
Pancreas and islet transplantations with diabetes mellitus
In some types of diabetes the insulin-producing organs are seriously damaged so that intensive insulin treatment is required. This usually concerns type 1 diabetes. At the LUMC the insulin producing cells can also be replaced by means of a pancreas transplantation. In most cases this is done in a combined kidney-pancreas transplantation for patients suffering from type 1 diabetes and kidney failure. With more than 400 (kidney-)pancreas transplantations Leiden has become one of the major centers of expertise for (kidney-) pancreas transplantations in Europe.
For patients suffering from type 1 diabetes, it is now possible to only isolate the Islets of Langerhans from a donor pancreas and to transplant these instead of transplanting the entire pancreas. The LUMC Transplant Center is the only center in the Netherlands both isolating and transplanting the Islets of Langerhans. This treatment requires extensive expertise and a good cooperation between a great number of different departments. By now more than 50 islet transplantations of donor organs have taken place. At the same time, a programme has been set up where islets isolated from the patient’s own pancreas are transplanted after it has had to be removed (islet autotransplantation).