Dr B. Siegerink (Bob)

Assistant professor


  • Thrombotic diseases
  • Vascular neurology
  • Causal inference


Bob Siegerink (1983) currently works at the Leiden University Medical Center, where he runs the program “quality and integrity of research”. This program is a combined effort of the department of clinical epidemiology and the directorate of research policy. The program combines policy development and implementation, (meta-) research and methodology development to advance the quality and integrity of science – both clinical and pre-clinical, both locally and (inter)nationally. Earlier work focused on thrombosis and neurovascular research, of which some projects continue to this day. 


Key publicaties

  • Andersson, H. M., Siegerink, B., Luken, B. M., Crawley, J. T. B., Algra, A., Lane, D. A., & Rosendaal, F. R. (2012). High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women. Blood, 119(6), 1555–60. doi:10.1182/blood-2011-09-380618.
  • Sigerink, B., Govers-Riemslag, J. W. P., Rosendaal, F. R., Ten Cate, H., & Algra, A. (2010). Intrinsic coagulation activation and the risk of arterial thrombosis in young women: results from the Risk of Arterial Thrombosis in relation to Oral contraceptives (RATIO) case-control study. Circulation, 122(18), 1854–61. doi:10.1161/CIRCULATIONAHA.110.943738.
  • Urbanus, R.T., Siegerink, B., Roest, M., Rosendaal, F. R., de Groot, P. G., & Algra, A. (2009). Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study. Lancet Neurology, 8(11), 998–1005. doi:10.1016/S1474-4422(09)70239-X .
  • Sigerink, B., Meltzer, M. E., de Groot, P. G., Algra, A., Lisman, T., & Rosendaal, F. R. (2011). Clot lysis time and the risk of myocardial infarction and ischaemic stroke in young women; results from the RATIO case-control study. British journal of haematology, 156(2), 252–8. doi:10.1111/j.1365-2141.2011.08935.x.


 Publicaties op PubMed van B. Siegerink


Siegerink, B. (2013). Prothrombotic factors and the risk of myocardial infarction and ischaemic stroke in young women: differences, similarities and implications (1st ed., p. 255). Den Haag: American Book Center - Anybook press. ISBN: 9789491030390

Personal website


twitter handle: @bobsiegerink


Leids Universitair Medisch Centrum
Gebouw 1
Kamer C7-101

Albinusdreef 2
2333 ZA Leiden
Tel: (+31)71 526 5635

Postzone C7-P
Postbus 9600
2300 RC Leiden

E-mail: B.Siegerink@lumc.nl