Dr ir R. de Mutsert (Renée)

Assistant professor


  • (Abdominal) obesity
  • Body composition
  • Nutrition
  • Lifestyle and chronic diseases


Renée de Mutsert has a MSc degree in ‘Nutrition and Health’ (Wageningen University, the Netherlands) and a PhD degree in Clinical Epidemiology (Leiden University and Medical Center (LUMC), the Netherlands). Currently, she coordinates a large prospective cohort study, the Netherlands Epidemiology of Obesity study, to unravel underlying mechanisms of obesity-related diseases. In addition, she teaches epidemiology to (bio)medical students. She conducts research on the role of dietary intake, physical activity, and body composition in the development of insulin resistance, type 2 diabetes and cardiovascular disease. She is particularly interested in the causes and consequences of visceral fat accumulation. 


 Key publicaties

  • Hillebrand S, Swenne CA, Gast KB, Maan AC, le Cessie S, Jukema JW, Rosendaal FR, den Heijer M, de Mutsert R. The role of insulin resistance in the association between body fat and autonomic function. Nutr Metab Cardiovasc Dis 2014;doi: 10.1016/j.numecd.2014.07.009
  • de Mutsert R, Sun Q, Willett WC, Hu FB, van Dam RM. Overweight in Early Adulthood, Adult Weight Change and Risk of Type 2 Diabetes, Cardiovascular Diseases, and Certain Cancers in Men: a Cohort Study. Am J Epidemiol 2014;179:1353-1365
  • de Mutsert R, Nijhoff MF, Vandenbroucke JP. BMI and mortality among adults with incident type 2 diabetes. N Engl J Med. 2014 Apr 3;370(14):1361
  • Hillebrand S, de Mutsert R, Christen T, Maan AC, Jukema JW, Lamb HJ, de Roos A, Rosendaal FR, den Heijer M, Swenne CA; NEO Study Group. Body fat, especially visceral fat, is associated with electrocardiographic measures of sympathetic activation. Obesity (Silver Spring) 2014;22:1553-1559
  • Gast KB, Smit JW, den Heijer M, Middeldorp S, Rippe RC, le Cessie S, de Koning EJ, Jukema JW, Rabelink TJ, de Roos A, Rosendaal FR, de Mutsert R; NEO study group. Abdominal adiposity largely explains associations between insulin resistance, hyperglycemia and subclinical atherosclerosis: the NEO study. Atherosclerosis 2013;229:423-429
  • de Mutsert R, den Heijer M, Rabelink TJ, Smit JW, Romijn JA, Jukema JW, de Roos A, Cobbaert CM, Kloppenburg M, le Cessie S, Middeldorp S, Rosendaal FR. The Netherlands Epidemiology of Obesity (NEO) study: study design and data collection. Eur J Epidemiol 2013;28:513-523
  • de Mutsert R, Grootendorst DC, Boeschoten EW, Brandts H, van Manen JG, Krediet RT, Dekker FW; NECOSAD Study Group. Subjective global assessment of nutritional status is strongly associated with mortality in chronic dialysis patients. Am J Clin Nutr 2009;89:787-793
  • de Mutsert R, Snijder MB, van der Sman-de Beer F, Seidell JC, Boeschoten EW, Krediet RT, Dekker JM, Vandenbroucke JP, Dekker FW. The association between body mass index and mortality is similar in the hemodialysis population and the general population at high age and equal duration of follow-up. J Am Soc Nephrol 2007;18:967-974

Publicaties op PubMed van R. de Mutsert


Leids Universitair Medisch Centrum
Gebouw 1
Kamer C-07-098

Albinusdreef 2
2333 ZA Leiden
Tel: +31 71 526 1384

Postzone C7-P
Postbus 9600
2300 RC Leiden

E-mail: R.de_Mutsert@lumc.nl