Clinical Trials Registers en lopend onderzoek

Clinical Trials Registries

Het Projectenbureau van het LUMC is het eerste aanspreekpunt bij het schrijven van een protocol en het goed opzetten van een clinical trial.

www.trialregister.nl Nederlands Trialregister: zoeken naar trials en registratie van trials om voor publicatie in een aantal gezaghebbende medische tijdschriften in aanmerking te kunnen komen.

https://www.clinicaltrialsregister.eu/ Europees register met informatie over de ongeveer 10.000 lopende farmaceutische trials in de EU.

apps.who.int/trialsearch/ International Clinical Trials Registry (WHO): beoogt één toegangspoort te vormen naar informatie over alle lopende en afgesloten clinical trials.

www.clinicaltrials.gov clinical trials-site van de U.S. National Institutes of Health (NIH).

www.circare.org/registries.htm overzicht van diverse clinical trials registries gerangschikt op vakgebied of (non) profit-organisatie.

en.wikipedia.org/wiki/clinical_trials_registry biedt ondermeer een overzicht van clinical trials registries per land.

isrctn.org International Standard Randomised Controlled Trial Number Register:
verstrekt unieke nummers aan clinical trials, zodat de voortgang van de trial makkelijker te volgen is.

Clinical Trials Result

www.nlm.nih.gov/services/ctresults.html  pagina van de National Library of Medicine met veelgestelde vragen over clinical trials results en met links naar vindplaatsen.

Informatie óver clinical trials

www.trialsjournal.com  open access-tijdschrift met artikelen over diverse aspecten aangaande clinical trials.


Informatie voor patiënten over clinical trials

www.nlm.nih.gov/medlineplus/clinicaltrials.html
www.centerwatch.com

Zoeken naar clinical trials in diverse databanken                               


Cochrane Library

Zoek op het onderwerp in het deelbestand “Cochrane Center Register of  Controlled Trials”


PubMed

  1. Zoeken naar specifieke trial 
    a1. zoek op de naam van de trial of het trialnummer.
    a2. zoek op de naam van de verantwoordelijke onderzoeker bij de trial:
    (disease AND (last name[ir] OR last name[au]) ir = investigator
  2. Zoeken op onderwerp gecombineerd met
    b1. de limit: clinical trial[pt] (= clinical trials als publication type)
    Let op! Bij het gebruiken van een limit in PubMed worden de niet-geïndexeerde referenties (zoals de meest recente) niet meegenomen in de zoekactie
    b2. één van onderstaande filters (copy-paste in zoekveld): 

    Clinical study filter (> 8.7 miljoen referenties op 20-03-2019)
    ("Case Reports"[pt] OR "Case Report"[tiab] OR "Case Reports"[tiab] OR "Clinical Conference"[pt] OR "Clinical Conference"[tiab] OR "Clinical Conferences"[tiab] OR "Clinical Studies as Topic"[mesh] OR "Clinical Study"[pt] OR "clinical study"[tiab] OR  "clinical studies"[tiab] OR "clinical trial"[pt] OR "clinical trial"[tiab] OR "clinical trials as topic"[mesh] OR "clinical trials"[tiab] OR "Comparative Study"[pt] OR "Comparative study"[tiab] OR "Comparative Studies"[tiab] OR "control groups"[mesh] OR "control group"[tiab] OR "control groups"[tiab] OR "controlled clinical trial"[pt] OR "controlled clinical trials as topic"[mesh] OR "cross-over studies"[mesh] OR "cross over study"[tiab] OR "cross over studies"[tiab] OR "double-blind method"[mesh] OR "double blind"[tiab] OR "evaluation studies as topic"[mesh] OR "Evaluation Studies"[pt] OR "Evaluation Study"[tiab] OR"Evaluation Studies"[tiab] OR "follow-up studies"[mesh] OR "follow up study"[tiab] OR "follow up studies"[tiab] OR "groups"[tiab] OR "Multicenter Study"[pt] OR "Multicenter Study"[tiab] OR "Multicenter Studies"[tiab] OR "Observational Studies as Topic"[mesh] OR "Observational Study"[pt] OR "Observational Study"[tiab] OR "Observational Studies"[tiab] OR "Patient Selection"[mesh] OR "Patient Selection"[tiab] OR "Phase 1 trial"[tiab] OR "Phase 2 trial"[tiab] OR "Phase 3 trial"[tiab] OR "Phase 4 trial"[tiab] OR "Phase I trial"[tiab] OR "Phase II trial"[tiab] OR "Phase III trial"[tiab] OR "Phase IV trial"[tiab] OR "Phase one trial"[tiab] OR "Phase two trial"[tiab] OR "Phase three trial"[tiab] OR "placebos"[mesh] OR placebo*[tiab] OR placebos*[tiab] OR "pragmatic clinical trial"[pt] OR "prospective studies"[mesh] OR "prospective study"[tiab] OR "prospective studies"[tiab] OR "RaCT"[tiab] OR "RaCTs"[tiab] OR "random allocation"[mesh] OR "randomised "[tiab] OR "randomized controlled trial"[pt] OR "randomized controlled trials as topic"[mesh] OR "randomized"[tiab] OR random*[tiab] OR "RCT"[tiab] OR "RCTs"[tiab] OR "Research Design"[MeSH:noexp] OR "Research design"[tiab] OR "Research designs"[tiab] OR "single blind"[tiab] OR "single-blind method"[mesh] OR ((single*[tiab] OR double*[tiab] OR triple*[tiab]) AND (blind*[tiab] OR mask*[tiab])) OR "trial"[tiab] OR "trials"[tiab] OR "Twin Study"[pt] OR "Twin Study"[tiab] OR "Twin Studies"[tiab] OR volunteer*[tiab])

    (Randomised) Controlled Trials ((R)CTs) (> 4.0 miljoen referenties op 20-03-2019)
    ("clinical trial"[pt] OR "clinical trial"[tiab] OR "clinical trials as topic"[mesh] OR "clinical trials"[tiab] OR "control groups"[mesh] OR "control group"[tiab] OR "control groups"[tiab] OR "controlled clinical trial"[pt] OR "controlled clinical trials as topic"[mesh] OR "cross-over studies"[mesh] OR "cross over study"[tiab] OR "cross over studies"[tiab] OR "double-blind method"[mesh] OR "double blind"[tiab] OR "evaluation studies as topic"[mesh] OR "follow-up studies"[mesh] OR "follow up study"[tiab] OR "follow up studies"[tiab] OR "placebos"[mesh] OR placebo*[tiab] OR placebos*[tiab] OR "pragmatic clinical trial"[pt] OR "prospective studies"[mesh] OR "prospective study"[tiab] OR "prospective studies"[tiab] OR "RaCT"[tiab] OR "RaCTs"[tiab] OR "random allocation"[mesh] OR "randomised "[tiab] OR "randomized controlled trial"[pt] OR "randomized controlled trials as topic"[mesh] OR "randomized"[tiab] OR random*[tiab] OR "RCT"[tiab] OR "RCTs"[tiab] OR "Research Design"[MeSH:noexp] OR "Research design"[tiab] OR "Research designs"[tiab] OR "single blind"[tiab] OR "single-blind method"[mesh] OR ((single*[tiab] OR double*[tiab] OR triple*[tiab]) AND (blind*[tiab] OR mask*[tiab])) OR volunteer*[tiab] OR "trial"[ti] OR "trials"[ti])
  1. Zoeken naar specifieke trial
    a1. zoek op de naam van de trial of het trialnummer.
    a2. zoek op de naam van de verantwoordelijke onderzoeker bij de trial
  2. Zoeken op onderwerp gecombineerd met
    b1. een limit > Clinical Trial
    b2. één van onderstaande filters (copy-paste in zoekveld):

    Clinical study filter (> 11.4 miljoen referenties, waaronder 1.2 miljoen meeting abstracts op 24-11-2016)
    (exp case report/ OR "Case Report".ti,ab. OR "Case Reports".ti,ab. OR exp case control study/ OR "case control study".ti,ab. OR "case control studies".ti,ab. OR exp case study/ OR "case study".ti,ab. OR "case studies".ti,ab. OR "Clinical Conference".ti,ab. OR "Clinical Conferences".ti,ab. OR exp clinical study/ OR "clinical study".ti,ab. OR "clinical studies".ti,ab. OR exp clinical trial/ OR "clinical trial".ti,ab. OR "clinical exp trial (topic)"/ OR "clinical trials".ti,ab. OR exp comparative study/ OR "Comparative study".ti,ab. OR "Comparative Studies".ti,ab. OR community trial/ OR "community trials".ti,ab. OR "community trials".ti,ab. OR "control group"/ OR "control group".ti,ab. OR "control groups".ti,ab. OR exp controlled clinical trial/ OR exp "controlled clinical trial (topic)"/ OR "cross over study".ti,ab. OR "cross over studies".ti,ab. OR exp evaluation study/ OR "Evaluation Study".ti,ab. OR "Evaluation Studies".ti,ab. OR exp family study/ OR "family study".ti,ab. OR "family studies".ti,ab. OR follow up/ OR "follow up study".ti,ab. OR "follow up studies".ti,ab. OR "groups".ti,ab. OR exp intervention study/ OR "intervention study".ti,ab. OR "intervention studies".ti,ab. OR exp longitudinal study/ OR "longitudinal study".ti,ab. OR "longitudinal studies".ti,ab. OR exp major clinical study/ OR "major clinical study".ti,ab. OR "major clinical studies".ti,ab. OR multicenter study/ OR "Multicenter Study".ti,ab. OR "Multicenter Studies".ti,ab. OR observational study/ OR "Observational Study".ti,ab. OR "Observational Studies".ti,ab. OR exp open study/ OR "open study".ti,ab. OR "open studies".ti,ab. OR patient selection/ OR "Patient Selection".ti,ab. OR exp "phase 1 clinical trial (topic)"/ OR exp "phase 2 clinical trial (topic)"/ OR exp "phase 3 clinical trial (topic)"/ OR exp "phase 4 clinical trial (topic)"/ OR "Phase 1 trial".ti,ab. OR "Phase 2 trial".ti,ab. OR "Phase 3 trial".ti,ab. OR "Phase 4 trial".ti,ab. OR "Phase I trial".ti,ab. OR "Phase II trial".ti,ab. OR "Phase III trial".ti,ab. OR "Phase IV trial".ti,ab. OR "Phase one trial".ti,ab. OR "Phase two trial".ti,ab. OR "Phase three trial".ti,ab. OR placebo/ OR placebo*.ti,ab. OR placebos*.ti,ab. OR prospective study/ OR "prospective study".ti,ab. OR "prospective studies".ti,ab. OR "RaCT".ti,ab. OR "RaCTs".ti,ab. OR "randomised".ti,ab. OR exp randomization/ OR randomized controlled trial/ OR "randomized controlled trial (topic)"/ OR "randomized".ti,ab. OR random*.ti,ab. OR "RCT".ti,ab. OR "RCTs".ti,ab. OR exp retrospective study/ OR "retrospective study".ti,ab. OR "retrospective studies".ti,ab. OR study design/ OR "study design".ti,ab. OR "study designs".ti,ab. OR "single blind".ti,ab. OR single blind procedure/ OR double blind procedure/ OR triple blind procedure/ OR ((single*.ti,ab. OR double*.ti,ab. OR triple*.ti,ab.) AND (blind*.ti,ab. OR mask*.ti,ab.)) OR "trial".ti,ab. OR "trials".ti,ab. OR exp twins/ OR "Twin Study".ti,ab. OR "Twin Studies".ti,ab. OR volunteer*.ti,ab.)

    (Randomised) Controlled Trials ((R)CTs) (> 4.5 miljoen referenties, waarvan 0.8 miljoen meeting abstracts op 24-11-2016)
    (exp clinical trial/ OR "clinical trial".ti,ab. OR "clinical exp trial (topic)"/ OR "clinical trials".ti,ab. OR "control group"/ OR "control group".ti,ab. OR "control groups".ti,ab. OR exp controlled clinical trial/ OR exp "controlled clinical trial (topic)"/ OR "cross over study".ti,ab. OR "cross over studies".ti,ab. OR exp evaluation study/ OR follow up/ OR "follow up study".ti,ab. OR "follow up studies".ti,ab. OR placebo/ OR placebo*.ti,ab. OR placebos*.ti,ab. OR prospective study/ OR "prospective study".ti,ab. OR "prospective studies".ti,ab. OR "RaCT".ti,ab. OR "RaCTs".ti,ab. OR "randomised".ti,ab. OR exp randomization/ OR randomized controlled trial/ OR "randomized controlled trial (topic)"/ OR "randomized".ti,ab. OR random*.ti,ab. OR "RCT".ti,ab. OR "RCTs".ti,ab. OR exp retrospective study/ OR "retrospective study".ti,ab. OR "retrospective studies".ti,ab. OR study design/ OR "study design".ti,ab. OR "study designs".ti,ab. OR "single blind".ti,ab. OR single blind procedure/ OR double blind procedure/ OR triple blind procedure/ OR ((single*.ti,ab. OR double*.ti,ab. OR triple*.ti,ab.) AND (blind*.ti,ab. OR mask*.ti,ab.)) OR volunteer*.ti,ab. OR "trial".ti. OR "trials".ti.)

Web of Science

  1. Zoeken naar specifieke trial 
    a1. zoek op de naam van de trial of het trialnummer.
    a2. zoek op de naam van de verantwoordelijke onderzoeker bij de trial
  2. Zoeken op onderwerp gecombineerd met
    b1. een limit zoeken kan niet, want er is geen clinical trial-limit in WoS
    b2. onderstaand filter (copy-paste in zoekveld): (> 5.0 miljoen op 31-01-17)
    Onderstaande strategie functioneert in het Advanced Search-scherm, niet in Basic Search.

    TS=("trial"  OR "trials" OR "clinical trial*" OR "RCT" OR "RCTS" OR "random*" OR "latin square" OR "placebo*" OR "methodology" OR "triangulation" OR "case control*" OR "crossover procedure" OR "cross-over procedure" OR "evaluation" OR "follow up" OR "controlled stud*" OR "prospective stud*" OR "cross-over stud*" OR "crossover stud*" OR "correlational stud*" OR "cross-sectional stud*" OR "crosssectional stud*" OR "comparative stud*" OR "retrospective stud*" OR "clinical stud*" OR "intervention stud*" OR "longitudinal stud*" OR "cohort*" OR "control group*" OR "pretest posttest design" OR (("single" OR "double" OR "treble" OR "triple") AND ("mask*" OR "blind*"))) 

PsycINFO (via EBSCO)

  1. Zoeken naar specifieke trial 
    a1. zoek op de naam van de trial of het trialnummer.
    a2. zoek op de naam van de verantwoordelijke onderzoeker bij de trial
  2. Zoeken op onderwerp gecombineerd met
    b1. met een limit: Methodology: Treatment outcome / Clinical Trial (> 18.000 referenties)
    b2. onderstaand filter (copy-paste in zoekveld): (> 50.000 referenties)

    (DE "Clinical Trials+" OR TX clinical trial OR TX clinical trials OR TX randomized OR TX randomised)


Boeken

Boeken over clinical trials zijn te vinden in de rubrieken QV 771.1. en WA 950

Lopend onderzoek in Nederland

NARCIS biedt toegang tot wetenschappelijke informatie waaronder (open access) publicaties afkomstig uit de repositories van alle Nederlandse universiteiten, KNAW, NWO en een aantal wetenschappelijke instellingen, datasets van DANS en beschrijvingen van onderzoeksprojecten, onderzoekers en onderzoeksinstituten.
Zoeken in alléén de Leidse repository kan via Institutionele Repository Universiteit Leiden.

www.nhg.org/lopend-huisartsgeneeskundig-onderzoek Lopend huisartsgeneeskundig onderzoek

Lopend onderzoek buiten Nederland

België

www.researchportal.be FRIS Vlaams onderzoeksportaal

Groot-Britannië

www.nihr.ac.uk National Institute for Health Research (UK)

Europese Gemeenschap

http://cordis.europa.eu CORDIS Community Research & Development Information - the gateway of European Research and Development

http://ec.europa.eu/research EC European Research & Innovation sitemap

www.eurocris.org EUROCRIS Current Research Information Systems

Internationaal

worldwidescience.org/wws: World Wide Science: geeft toegang tot nationale en internationale wetenschappelijke databanken