PhD Candidate Biostatistics

Teaching & research staff

Your position

Do you hold a master’s degree in mathematics, statistics, biostatistics or a similar subject with a strong mathematical background? Do you have a profound interest in medical applications and good communicative skills in English? Then you might be the PhD candidate we are looking for!

In short

• You will develop novel statistical methods with application in medical data as part of the NIH grant “Biomarker signatures for Duchene Muscular Dystrophy”
• Your research will focus on methods for estimating dynamic associations and deriving predictions based on high-dimensional longitudinal biomarkers
• You hold a master’s degree in mathematics, statistics, biostatistics or a similar subject with a strong mathematical background, and have a profound interest in medical applications
• The Medical Statistics Section of the Department of Biomedical Data Sciences is the top ranking center for medical statistics in the Netherlands

What you do

As a PhD student in the Department of Biomedical Data Sciences, you will develop novel statistical methods with application in medical data as part of the NIH grant “Biomarker signatures for Duchene Muscular Dystrophy”. Your research will focus on methods for estimating dynamic associations and deriving predictions based on high-dimensional longitudinal biomarkers and you will be supervised by Dr. Roula Tsonaka (Medical Statistics Section). You will collaborate closely with biomedical researchers from the Duchene Muscular Dystrophy (DMD) genetic therapy group in the Department of Human Genetics under the supervision of Dr. Pietro Spitali (Human Genetics) and with our international collaborators in the context of the NIH grant that funds this position. You will need to write software to make your methods usable by others, and you will be expected to teach medical students (at most 10% of your time). Finally, you will present your results locally and at international biostatistics and DMD conferences, and publish your results in statistics and medical journals and in a PhD thesis.

What we ask

You hold a master’s degree in mathematics, statistics, biostatistics or a similar subject with a strong mathematical background, and have a profound interest in medical applications. You have good communicative skills in English and enjoy collaborating with researchers outside your own field. Excellent programming skills in R or other statistical programming languages are essential. Background and experience with longitudinal data analysis methods, i.e., random effects models and Bayesian statistics is not mandatory but will be very useful.

More information

You will be given an employment contract for the production of a PhD thesis for the duration of the program with a maximum of four years. The salary amounts to € 2,631 gross per month in the first year, up to a maximum of € 3,336 in the last year with fulltime employment (scale Pro, CLA UMC).

For this vacancy references can be requested. Also, the application procedure may involve a presentation. If you are invited for a first interview, this will be take place on January, 10th 2023 either in person or online.

Applications from employment/recruitment agencies will not be considered

Asel Arykbaeva

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Your workplace

Leiden University Medical Center (LUMC) is a modern knowledge center with over 7,000 staff members who are passionate about combating disease and improving patient care through scientific research. The Medical Statistics Section of the Department of Biomedical Data Sciences is the top ranking center for medical statistics in the Netherlands, and has a strong reputation for research in high-dimensional data, longitudinal data analysis, statistical genetics, survival analysis and causality. Here, you will be embedded in a large department with 15 tenured research statisticians, 4 postdocs and 9 PhD students. Positioned within the applied context of the Medical Center, the group has intensive collaboration with medical researchers.

Your career at the LUMC

Getting better at ground-breaking levels; that's our mission. This applies not only to healthcare, but also to our employees. In order to be able to continue to learn and develop, we offer internal and external training. You are also entitled to an end-of-year bonus (8,3%), holiday allowance, sports budget and bicycle scheme. In addition you can make use of our pension scheme at ABP, where LUMC pays no less than 70% of your pension premium, causing your net salary to be higher.

Contact: Roula Tsonaka, assistant professor, Medical Statistics Section, Department of Biomedical Data Sciences

e-mail: s.tsonaka@lumc.nl

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