Hans Tanke


  • Professor
  • Cell growth and Transcription regulation



  • Name: Hans J. Tanke;born 26-02-1952
  • Leiden University Medical Center
  • Einthovenweg 20 Bldg 2. PO Box 9600
  • 2300 RC Leiden; The Netherlands
  • Email: h.j.tanke@lumc.nl

  • 1977 Doctoral Degree in Biochemistry, Utrecht university (with Immunology and Clinical Chemistry)
  • 1977 Start PhD study Leiden University
  • 1978 Three months training at Lawrence Livermore Laboratories; Livermore CA, USA
  • 1982 PhD, University of Leiden, The Netherlands Cytochemical and Cytometric Methods for DNA en RNA analysis (Promotor P. van Duijn, J.S. Ploem)

Post doctoral training:

  • 1982 - 1988 Laboratory of Cytochemistry and Cytometry, Leiden
  • 1982 Department of Pathology, Innsbruck (2 months).
  • 1987 - 1994 Part time consultant at the Hochschule Hannover; Germany

Professional experience:

  • 1988 - 1993 Associate Professor;  University of Leiden
  • 1990  Visiting Professor; University of Bologna and Urbino; Italy
  • 1991 - 1997 Visiting Professor at VUB Brussels
  • 1993 - present Professor of Cell Biology (Analytical Cytology)
  • 1997 - 2017 Chairman Department of Molecular Cell Biology
  • 1998 - 2017 Member of the board research of division 5 of the LUMC
  • 2013 - 2017 Member of the board of division 4 of the LUMC
  • 2015 - 2017 Appointed as LUMC division 4 board member of education
  • 2012 - present Professor University of Leiden Faculty Wis- en Natuurkunde (Bioimaging)
  • 2013 - present Professor Medical Delta / Bionanoscience group
  • 2014 - present Director GENOMESCAN
  • 2014 - present Member Advisory Board Institute of Biology Leiden
  • 2014 - present Member Advisory Board Boerhaave Museum Leiden
  • 2015 - present co-director of the Casimir Research School Delft-Leiden

Honors and awards:

  • 1982 International "C.E. Alken-Preis" for urological Research
  • 1987 "Bisschof-Preis, German  Urology" (as co-author).
  • 1989 PIONIER grant; NWO; the  Netherlands
  • 2008 Membership services award International Society for Advanced Cytometry


  • Member Council International Society for Analytical Cytology (two terms)
  • Member Council Society for Analytical Cellular Pathology (one term)

Editorial boards:

  • Cytometry (until 2006)
  • Journal of Microscopy (until 2005)
  • Protocols in cytometry (until 2005)
  • Bioanalytical reviews (recently founded)
  • Cellular Oncology (past)
  • Journal of Structural Biology (past)

Scientific advisory boards and consultancy:

  • VYSIS-USA: member SAB until 2002
  • Kreatech Biotechnology (Amsterdam-NL): Chairman SAB until present
  • Leica Microsystems (Wetzlar-Germany): member of supervisory board 1999-2005
  • Consultant for Applied Imaging (San Jose CA/Newcastle UK), Orasure (Bethlehem-PA), PerkinElmer (USA), Boehringer-Roche (Germany)
  • Member of the AMMRF International Technical and User Advisory Group (ITUAG), Australia


  • Undergraduate: Introduction Microscopy, Functional Morphology
  • Postgraduate: “Advanced microscopy”, “Medical imaging”


Supervision as promotor of 30 PhD students; member of thesis examination committees in more than 40 occasions (national; Leiden, Delft, Amsterdam, Enschede) and 2 (international: Finland and Denmark)

Research fields:

His present research field relates to the development of novel fluorescence based technology including advanced imaging to study the molecular composition of cells and chromosome. A special research focus is the analysis of molecular interactions in living cells using CSLM, FRAP and FRET-FLIM techniques. Aim is to unravel the molecular mechanisms that determine normal and abnormal cell function, aiming to understand the cause of inherited and acquired disease. He pioneered the development of novel fluorescent reporters and promoted the use of digital fluorescence microscopy for this purpose, one of the first Dutch programs awarded with a NWO Pioneer grant in 1989. In past decades his team has made many original contributions to the field of FISH and immunocytochemistry and automated microscopy. Since three years his team develops technology for point-of-care diagnosis of infectious diseases using saliva. Hans Tanke  is (co)-author of more than 300 scientific papers, and is (co)-inventor on 5 patents (see below).

The Department of Molecular Cell Biology that he chairs since 1997 has four main research programs: “Signal transduction in aging related diseases (cancer, diabetes, osteoporosis)”, “Gene regulation and cell differentiation (including gene therapy and stem cell research)”, “Neurosciences in Drosophila and rodents: from genes to neuronal networks” and “Microscopic imaging and technology” (see also https://www.lumc.nl/org/moleculaire-celbiologie/).


Leids Universitair Medisch Centrum
Gebouw 2

Einthovenweg 20
2333 ZC Leiden
Tel: 9200

Postzone S-1-P
Postbus 9600
2300 RC Leiden

E-mail: h.j.tanke@lumc.nl