Sebastiaan Heidt studied biomedical sciences and received his PhD degree in 2010 in the laboratory of Prof. Frans Claas on the characterization of B cell responses in relation to organ transplantation. Hereafter, he worked as a postdoctoral scientist in the laboratory of Prof. Kathryn Wood in Oxford for 2 years, mainly focusing on immune monitoring in kidney transplant recipients. Afterwards, he returned to Leiden to work as a senior postdoctoral scientist on the detection of HLA-specific memory B cells and the role of B cells in transplant rejection. Currently he is working as an associate professor, heading the research team of the laboratory of Immunogenetics and Transplantation Immunology of the LUMC. His main research interests are HLA epitope matching, the formation and detection of HLA-specific B cell memory, immune monitoring of transplant recipients, and personalized medicine by definition of acceptable HLA mismatches. This work is embedded in the LUMC Transplant Center. Furthermore, he is managing director of the Eurotransplant Reference Laboratory (ETRL), which is also situated in Leiden. The main tasks of the ETRL are external proficiency testing of Eurotransplant affiliated laboratories, as well as running the Eurotransplant Acceptable Mismatch program for highly sensitized patients.
Dr. Heidt is section editor ‘HLA in solid organ transplantation’ of the HLA journal, and member of the scientific committee of both the European Federation for Immunogenetics (EFI), and the American Society of Histocompatibility and Immunogenetics (ASHI). He is counselor of the International HLA and Immunogenetics Workshop (IHIWS), and co-organiser of the 18th IHIWS, to be held in Amsterdam in 2021.