Ramon Arens studied Medical Biology at the University of Amsterdam and carried out his PhD research in the laboratory of Prof. René van Lier and Prof. Marinus van Oers at the Academic Medical Center on the role of the T cell costimulatory molecules CD27 and CD70. After obtaining his PhD in 2003, he performed postdoctoral research in the group of Prof. Ton Schumacher at the Immunology Division of the Netherlands Cancer Institute till 2006, which was followed by a position as a research scientist at the La Jolla Institute of Allergy and Immunology (LIAI) in San Diego.
Since 2010 he is group leader at the department of Immunology of Leiden University Medical Center. The research of Arens and his team focuses on fundamental and translational T cell immunobiology in (chronic) infections and cancer. The laboratory has gained extensive knowledge on T cell immunity, T cell costimulation, and development of immunotherapeutic strategies based on immunomodulatory agents, vaccination and adoptive T cell transfer.
Current research aims to dissect the mechanisms of effective immunotherapy by genetic screens and by using high-dimensional profiling techniques including mass cytometry and single cell RNA sequencing. The Arens lab is funded by grants from the Dutch Cancer Society (KWF), The Netherlands Organisation for Scientific Research (NWO), and the European Commission.