All publications

Publications:

  1. Chin PT, van der Linden M, van Harten EJ, Barendregt A, Rood MT, Koster AJ, van Leeuwen FW, de Mello Donega C, Heck AJ, Meijerink A. Enhanced luminescence of Ag nanoclusters via surface modification.. Nanotechnology 2013-Jan-28;24(7). (pubmed)
  2. Dekker P, Meissner A, Dirks RW, Slagboom PE, van Heemst D, Deelder AM, Tanke HJ, Westendorp RGJ, Maier AB. Human in vivo longevity is reflected in vitro by differential metabolism as measured by H-1-NMR profiling of cell culture supernatants. Molecular biosystems 2012-Dec-31;8(3):783-789. (pubmed)
  3. Alpar D, Szuhai K, Pajor G, Vojcek A, Ottoffy G, Kneif M, Poto L, Pajor L. SUB-CLONAL CYTOGENETIC HETEROGENEITY IN HIGH HYPERDIPLOID ACUTE LYMPHOBLASTIC LEUKAEMIA. Pediatric blood & cancer 2012-Dec-31;59(6):1034-1034. (pubmed)
  4. van der Laan AM, Vangemert AM, Dirks RW, Noordermeer JN, Fradkin LG, Tanke HJ, Jost CR. mRNA cycles through hypoxia-induced stress granules in live Drosophila embryonic muscles.. The international journal of developmental biology 2012-Dec-28;56(9):701-9. (pubmed)
  5. Raap AK, Tafrechi RSJ, van de Rijke FM, Pyle A, Wahlby C, Szuhai K, Ravelli RBG, de Coo RFM, Rajasimha HK, Nilsson M, Chinnery PF, Samuels DC, Janssen GMC. Non-Random mtDNA Segregation Patterns Indicate a Metastable Heteroplasmic Segregation Unit in m.3243A > G Cybrid Cells. Plos one 2012-Dec-18;7(12). (pubmed)
  6. Szuhai K, Hogendoorn PCW. 'The chicken or the egg?' dilemma strikes back for the controlling mechanism in chordoma. Journal of pathology 2012-Nov-30;228(3):261-265. (pubmed)
  7. Pillay N, Plagnol V, Tarpey PS, Lobo SB, Presneau N, Szuhai K, Halai D, Berisha F, Cannon SR, Mead S, Kasperaviciute D, Palmen J, Talmud PJ, Kindblom LG, Amary MF, Tirabosco R, Flanagan AM. A common single-nucleotide variant in T is strongly associated with chordoma. Nature genetics 2012-Nov-30;44(11):1185-1187. (pubmed)
  8. Downs JA, van Dam GJ, Changalucha JM, Corstjens PLAM, Peck RN, de Dood CJ, Bang H, Andreasen A, Kalluvya SE, van Lieshout L, Johnson WD, Fitzgerald DW. Association of Schistosomiasis and HIV Infection in Tanzania. American journal of tropical medicine and hygiene 2012-Nov-30;87(5):868-873. (pubmed)
  9. Meijer D, de Jong D, Pansuriya TC, van den Akker BE, Picci P, Szuhai K, Bovee JVGM. Genetic characterization of mesenchymal, clear cell, and dedifferentiated chondrosarcoma. Genes chromosomes & cancer 2012-Oct-31;51(10):899-909. (pubmed)
  10. Graveland AP, Braakhuis BJM, Eerenstein SEJ, de Bree R, Bloemena E, de Maaker M, van den Brekel MWM, Dijk F, Mesker WE, Tanke HJ, Leemans CR, Brakenhoff RH. Molecular diagnosis of minimal residual disease in head and neck cancer patients. Cellular oncology 2012-Oct-31;35(5):367-375. (pubmed)
  11. Calabuig-Farinas S, Benso RG, Szuhai K, Machado I, Lopez-Guerrero JA, de Jong D, Peydro A, San Miguel T, Navarro L, Pellin A, LLombart-Bosch A. Characterization of a New Human Cell Line (CH-3573) Derived from a Grade II Chondrosarcoma with Matrix Production. Pathology & oncology research 2012-Oct-31;18(4):793-802. (pubmed)
  12. Kruttner S, Stepien B, Noordermeer JN, Mommaas MA, Mechtler K, Dickson BJ, Keleman K. Drosophila CPEB Orb2A Mediates Memory Independent of Its RNA-Binding Domain. Neuron 2012-Oct-18;76(2):383-395. (pubmed)
  13. Alpar D, de Jong D, Savola S, Yigittop H, Kajtar B, Kereskai L, Pajor L, Szuhai K. MLPA is a powerful tool for detecting lymphoblastic transformation in chronic myeloid leukemia and revealing the clonal origin of relapse in pediatric acute lymphoblastic leukemia. Cancer genetics 2012-Sep-30;205(9):465-469. (pubmed)
  14. Pajor G, Alpar D, Szuhai K, Knief M, Poto L, Vojcek A, Ottoffy G, Pajor L. Novel Eight-target FISH Approach for Profiling Clonality of High-hyperdiploid Paediatric Acute Lymphoblastic Leukemia (HHD-pALL). European journal of cancer 2012-Jul-31;48. (pubmed)
  15. Dekker P, Gunn D, McBryan T, Dirks RW, van Heemst D, Lim FL, Jochemsen AG, Verlaan-de Vries M, Nagel J, Adams PD, Tanke HJ, Westendorp RGJ, Maier AB. Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts. Mechanisms of ageing and development 2012-Jul-31;133(7):498-507. (pubmed)
  16. Szuhai K, Cleton-Jansen AM, Hogendoorn PCW, Bovee JVMG. Molecular pathology and its diagnostic use in bone tumors. Cancer genetics 2012-May-31;205(5):193-204. (pubmed)
  17. Dekker P, van Baalen LM, Dirks RW, Slagboom PE, van Heemst D, Tanke HJ, Westendorp RGJ, Maier AB. Chronic Inhibition of the Respiratory Chain in Human Fibroblast Cultures: Differential Responses Related to Subject Chronological and Biological Age. Journals of gerontology series a-biological sciences and medical sciences 2012-May-31;67(5):456-464. (pubmed)
  18. Tornoczky T, Bogner B, Krausz T, Ottoffy G, Szuhai K. Angiomatoid Fibrous Histiocytoma: Pleomorphic Variant Associated with Multiplication of EWSR1-CREB1 Fusion Gene. Pathology & oncology research 2012-Apr-30;18(2):545-548. (pubmed)
  19. Mackintosh C, Ordonez JL, Garcia-Dominguez DJ, Sevillano V, Llombart-Bosch A, Szuhai K, Scotlandi K, Alberghini M, Sciot R, Sinnaeve F, Hogendoorn PCW, Picci P, Knuutila S, Dirksen U, Debiec-Rychter M, Schaefer KL, de Alava E. 1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma. Oncogene 2012-Mar-31;31(10):1287-1298. (pubmed)
  20. Knoops K, Barcena M, Limpens RWAL, Koster AJ, Mommaas AM, Snijder EJ. Ultrastructural Characterization of Arterivirus Replication Structures: Reshaping the Endoplasmic Reticulum To Accommodate Viral RNA Synthesis. Journal of virology 2012-Mar-31;86(5):2474-2487. (pubmed)
  21. Janssen A, van der Burg M, Szuhai K, Kops GJPL, Medema RH. DRUGGING CHROMOSOME INSTABILITY TO TARGET CANCER. Annals of oncology 2012-Mar-31;23:17-17. (pubmed)
  22. van de Giessen M, van der Laan A, Hendriks EA, Vidorreta M, Reiber JHC, Jost CR, Tanke HJ, Lelieveldt BPF. Fully Automated Attenuation Measurement and Motion Correction in FLIP Image Sequences. Ieee transactions on medical imaging 2012-Feb-28;31(2):461-473. (pubmed)
  23. Rinner B, Froehlich EV, Buerger K, Knausz H, Lohberger B, Scheipl S, Fischer C, Leithner A, Guelly C, Trajanoski S, Szuhai K, Liegl B. Establishment and detailed functional and molecular genetic characterisation of a novel sacral chordoma cell line, MUG-Chor1. International journal of oncology 2012-Feb-28;40(2):443-451. (pubmed)
  24. Taylor RM, Kashima TG, Ferguson DJ, Szuhai K, Hogendoorn PC, Athanasou NA. Analysis of stromal cells in osteofibrous dysplasia and adamantinoma of long bones. Modern pathology 2012-Jan-31;25(1):56-64. (pubmed)
  25. Pahl JHW, Ruslan SEN, Buddingh EP, Santos SJ, Szuhai K, Serra M, Gelderblom H, Hogendoorn PCW, Egeler RM, Schilham MW, Lankester AC. Anti-EGFR Antibody Cetuximab Enhances the Cytolytic Activity of Natural Killer Cells toward Osteosarcoma. Clinical cancer research 2012-Jan-15;18(2):432-441. (pubmed)
  26. Vertegaal ACO. Uncovering Ubiquitin and Ubiquitin-like Signaling Networks. Chemical reviews 2011-Dec-31;111(12):7923-7940. (pubmed)
  27. Pansuriya TC, van Eijk R, d'Adamo P, van Ruler MAJH, Kuijjer ML, Oosting J, Cleton-Jansen AM, van Oosterwijk JG, Verbeke SLJ, Meijer D, van Wezel T, Nord KH, Sangiorgi L, Toker B, Liegl-Atzwanger B, San-Julian M, Sciot R, Limaye N, Kindblom LG, Daugaard S, Godfraind C, Boon LM, Vikkula M, Kurek KC, Szuhai K, French PJ, Bovee JVMG. Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome. Nature genetics 2011-Dec-31;43(12):1256. (pubmed)
  28. Lenos K, Jochemsen AG. Functions of MDMX in the Modulation of the p53-Response. Journal of biomedicine and biotechnology 2011-Dec-31;. (pubmed)
  29. Hendriks IA, Schimmel J, Matic I, Mann M, Vertegaal ACO. Proteomic approaches to dissect ubiquitin-like signaling pathways. International journal of molecular medicine 2011-Dec-31;28. (pubmed)
  30. Spinnler C, Hedstrom E, Li H, de Lange J, Nikulenkov F, Teunisse AFAS, Verlaan-de Vries M, Grinkevich V, Jochemsen AG, Selivanova G. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX. Cell death and differentiation 2011-Nov-30;18(11):1736-1745. (pubmed)
  31. Freitas EL, Gribble SM, Simioni M, Vieira TP, Silva-Grecco RL, Balarin MAS, Prigmore E, Krepischi-Santos AC, Rosenberg C, Szuhai K, van Haeringen A, Carter NP, Gil-da-Silva-Lopes VL. Maternally Inherited Partial Monosomy 9p (pter -> p24.1) and Partial Trisomy 20p (pter -> p12.1) Characterized by Microarray Comparative Genomic Hybridization. American journal of medical genetics part a 2011-Nov-30;155A(11):2754-2761. (pubmed)
  32. Wolinski H, Kolb D, Hermann S, Koning RI, Kohlwein SD. A role for seipin in lipid droplet dynamics and inheritance in yeast. Journal of cell science 2011-Nov-15;124(22):3894-3904. (pubmed)
  33. Limpens RWAL, van der Schaar HM, Kumar D, Koster AJ, Snijder EJ, van Kuppeveld FJM, Barcena M. The transformation of enterovirus replication structures: a three-dimensional study of single- and double-membrane compartments. Mbio 2011-Oct-31;2(5). (pubmed)
  34. Corstjens PLAM, de Dood CJ, van der Ploeg-van Schip JJ, Wiesmeijer KC, Riuttamaki T, van Meijgaarden KE, Spencer JS, Tanke HJ, Ottenhoff THM, Geluk A. Lateral flow assay for simultaneous detection of cellular- and humoral immune responses. Clinical biochemistry 2011-Oct-31;44(14-15):1241-1246. (pubmed)
  35. Pansuriya TC, Oosting J, Verdegaal SHM, Flanagan AM, Sciot R, Kindblom LG, Hogendoorn PCW, Szuhai K, Bovee JVMG. Maffucci Syndrome: A Genome-Wide Analysis Using High Resolution Single Nucleotide Polymorphism and Expression Arrays on Four Cases. Genes chromosomes & cancer 2011-Sep-30;50(9):673-679. (pubmed)
  36. Janssen A, van der Burg M, Szuhai K, Kops GJPL, Medema RH. Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations. Science 2011-Sep-30;333(6051):1895-1898. (pubmed)
  37. Lenos K, de Lange J, Teunisse AFAS, Lodder K, Verlaan-de Vries M, Wiercinska E, van der Burg MJM, Szuhai K, Jochemsen AG. Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts. Molecular cancer 2011-Sep-12;10. (pubmed)
  38. Robanus-Maandag E, Bosch C, Amini-Nik S, Knijnenburg J, Szuhai K, Cervera P, Poon R, Eccles D, Radice P, Giovannini M, Alman BA, Tejpar S, Devilee P, Fodde R. Familial Adenomatous Polyposis-Associated Desmoids Display Significantly More Genetic Changes than Sporadic Desmoids. Plos one 2011-Sep-09;6(9). (pubmed)
  39. Diebolder CA, Koning RI, Stutterheim WM, Koster AJ, Gros P. Cryo electron tomographic visualization of antigen bound antibodies and fitting of atomic models. Molecular immunology 2011-Aug-31;48(14):1709-1709. (pubmed)
  40. Naderi EH, Jochemsen AG, Blomhoff HK, Naderi S. Activation of cAMP Signaling Interferes with Stress-Induced p53 Accumulation in ALL-Derived Cells by Promoting the Interaction between p53 and HDM2. Neoplasia 2011-Jul-31;13(7):653. (pubmed)
  41. Bos E, SantAnna C, Gnaegi H, Pinto RF, Ravelli RBG, Koster AJ, de Souza W, Peters PJ. A new approach to improve the quality of ultrathin cryo-sections; its use for immunogold EM and correlative electron cryo-tomography. Journal of structural biology 2011-Jul-31;175(1):62-72. (pubmed)
  42. Wang JW, Valentijn KM, de Boer HC, Dirven RJ, van Zonneveld AJ, Koster AJ, Voorberg J, Reitsma PH, Eikenboom J. Intracellular Storage and Regulated Secretion of Von Willebrand Factor in Quantitative Von Willebrand Disease. Journal of biological chemistry 2011-Jul-08;286(27). (pubmed)
  43. Corstjens PL, de Dood CJ, van der Ploeg-van Schip JJ, Wiesmeijer KC, Riuttamäki T, van Meijgaarden KE, Spencer JS, Tanke HJ, Ottenhoff TH, Geluk A. Lateral flow assay for simultaneous detection of cellular- and humoral immune responses.. Clinical biochemistry 2011-Jul-06;. (pubmed)
  44. van den Worm SH, Knoops K, Zevenhoven-Dobbe JC, Beugeling C, van der Meer Y, Mommaas AM, Snijder EJ. Development and RNA-Synthesizing Activity of Coronavirus Replication Structures in the Absence of Protein Synthesis.. Journal of virology 2011-Jun-30;85(11):5669-73. (pubmed)
  45. Sage JT, Zhang YB, McGeehan J, Ravelli RBG, Weik M, van Thor JJ. Infrared protein crystallography. Biochimica et biophysica acta-proteins and proteomics 2011-Jun-30;1814(6):760-777. (pubmed)
  46. Jennes I, de Jong D, Mees K, Hogendoorn PCW, Szuhai K, Wuyts W. Breakpoint characterization of large deletions in EXT1 or EXT2 in 10 Multiple Osteochondromas families. Bmc medical genetics 2011-Jun-26;12. (pubmed)
  47. Balke M, Neumann A, Szuhai K, Agelopoulos K, August C, Gosheger G, Hogendoorn PCW, Athanasou N, Buerger H, Hagedorn M. A short-term in vivo model for giant cell tumor of bone. Bmc cancer 2011-Jun-13;11. (pubmed)
  48. Tjon JML, Kooy-Winkelaar YMC, Tack GJ, Mommaas AM, Schreurs MWJ, Schilham MW, Mulder CJ, van Bergen J, Koning F. DNAM-1 Mediates Epithelial Cell-Specific Cytotoxicity of Aberrant Intraepithelial Lymphocyte Lines from Refractory Celiac Disease Type II Patients. Journal of immunology 2011-Jun-01;186(11):6304-6312. (pubmed)
  49. Karuppasamy M, Nejadasl FK, Vulovic M, Koster AJ, Ravelli RBG. Radiation damage in single-particle cryo-electron microscopy: effects of dose and dose rate. Journal of synchrotron radiation 2011-May-31;18:398-412. (pubmed)
  50. Bouwman P, Drost R, Klijn C, Pieterse M, van der Gulden H, Song JY, Szuhai K, Jonkers J. Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression. Journal of pathology 2011-May-31;224(1):10-21. (pubmed)
  51. Valentijn KM, Sadler JE, Valentijn JA, Voorberg J, Eikenboom J. Functional architecture of Weibel-Palade bodies. Blood 2011-May-12;117(19):5033-5043. (pubmed)
  52. Ilett EJ, Barcena M, Errington-Mais F, Griffin S, Harrington KJ, Pandha HS, Coffey M, Selby PJ, Limpens RWAL, Mommaas M, Hoeben RC, Vile RG, Melcher AA. Internalization of Oncolytic Reovirus by Human Dendritic Cell Carriers Protects the Virus from Neutralization. Clinical cancer research 2011-May-01;17(9):2767-2776. (pubmed)
  53. Buddingh EP, Schilham MW, Eriaty S, Ruslan N, Berghuis D, Szuhai K, Suurmond J, Taminiau AHM, Gelderblom H, Egeler RM, Serra M, Hogendoorn PCW, Lankester AC. Chemotherapy-resistant osteosarcoma is highly susceptible to IL-15-activated allogeneic and autologous NK cells. Cancer immunology immunotherapy 2011-Apr-30;60(4):575-586. (pubmed)
  54. Wiweger MI, Avramut CM, de Andrea CE, Prins FA, Koster AJ, Ravelli RBG, Hogendoom PCW. Cartilage ultrastructure in proteoglycan-deficient zebrafish mutants brings to light new candidate genes for human skeletal disorders. Journal of pathology 2011-Mar-31;223(4):531-542. (pubmed)
  55. Hutteman M, Mieog JSD, van der Vorst JR, Dijkstra J, Kuppen PJK, van der Laan AMA, Tanke HJ, Kaijzel EL, Que I, van de Velde CJH, Lowik CWGM, Vahrmeijer AL. Intraoperative near-infrared fluorescence imaging of colorectal metastases targeting integrin alpha(v)beta(3) expression in a syngeneic rat model. Ejso 2011-Mar-31;37(3):252-257. (pubmed)
  56. Szuhai K, Jennes I, de Jong D, Bovee JVMG, Wiweger M, Wuyts W, Hogendoorn PCW. Tiling Resolution Array-CGH Shows That Somatic Mosaic Deletion of the EXT Gene is Causative in EXT Gene Mutation Negative Multiple Osteochondromas Patients. Human mutation 2011-Feb-28;32(2). (pubmed)
  57. Presneau N, Shalaby A, Ye HT, Pillay N, Halai D, Idowu B, Tirabosco R, Whitwell D, Jacques TS, Kindblom LG, Bruderlein S, Moller P, Leithner A, Liegl B, Amary FM, Athanasou NN, Hogendoorn PCW, Mertens F, Szuhai K, Flanagan AM. Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study. Journal of pathology 2011-Feb-28;223(3):327-335. (pubmed)
  58. Bronkhorst IHG, Ly LV, Jordanova ES, Vrolijk J, Versluis M, Luyten GPM, Jager MJ. Detection of M2-Macrophages in Uveal Melanoma and Relation with Survival. Investigative ophthalmology & visual science 2011-Feb-28;52(2):643-650. (pubmed)
  59. Pansuriya TC, Oosting J, Krenacs T, Taminiau AHM, Verdegaal SHM, Sangiorgi L, Sciot R, Hogendoorn PCW, Szuhai K, Bovee JVMG. Genome-wide analysis of Ollier disease: Is it all in the genes?. Orphanet journal of rare diseases 2011-Jan-14;6. (pubmed)
  60. Hutteman M, Mieog JS, van der Vorst JR, Dijkstra J, Kuppen PJ, van der Laan AM, Tanke HJ, Kaijzel EL, Que I, van de Velde CJ, Löwik CW, Vahrmeijer AL. Intraoperative near-infrared fluorescence imaging of colorectal metastases targeting integrin α(v)β(3) expression in a syngeneic rat model.. European journal of surgical oncology : the journal of the european society of surgical oncology and the british association of surgical oncology 2011-Jan-05;. (pubmed)
  61. The 3-D Architecture of Enterovirus Replication Factories. . (pubmed)
  62. Wiegant J, Brouwer AK, Tanke HJ, Dirks RW. Visualizing nucleic acids in living cells by fluorescence in vivo hybridization.. Methods in molecular biology (clifton, n.j.) 2010-Dec-31;659. (pubmed)
  63. Vulovic M, Brandt PL, Ravelli RBG, Koster AJ, van Vliet LJ, Rieger B. ESTIMATION OF DEFOCUS AND ASTIGMATISM IN TRANSMISSION ELECTRON MICROSCOPY. 2010 7th ieee international symposium on biomedical imaging: from nano to macro 2010-Dec-31;:1121-1124. (pubmed)
  64. Mohseny AB, Tieken C, van der Velden PA, Szuhai K, de Andrea C, Hogendoorn PCW, Cleton-Jansen AM. Small Deletions but not Methylation Underlie CDKN2A/p16 Loss of Expression in Conventional Osteosarcoma. Genes chromosomes & cancer 2010-Dec-31;49(12):1095-1103. (pubmed)
  65. Krepischi AC, Knijnenburg J, Bertola DR, Kim CA, Pearson PL, Bijlsma E, Szuhai K, Kok F, Vianna-Morgante AM, Rosenberg C. Two distinct regions in 2q24.2-q24.3 associated with idiopathic epilepsy. Epilepsia 2010-Dec-31;51(12):2457-2460. (pubmed)
  66. Heyning FH, Jansen PM, Hogendoorn PCW, Szuhai K. Array-based comparative genomic hybridisation analysis reveals recurrent chromosomal alterations in primary diffuse large B cell lymphoma of bone. Journal of clinical pathology 2010-Dec-31;63(12):1095-1100. (pubmed)
  67. Briegel A, Chen SY, Koster AJ, Plitzko JM, Schwartz CL, Jensen GJ. CORRELATED LIGHT AND ELECTRON CRYO-MICROSCOPY. Methods in enzymology, vol 481: cryo-em, part a - sample preparation and data collection 2010-Dec-31;481:317-341. (pubmed)
  68. Ye H, Shalaby A, Presneau N, Pillay N, Idowu B, Halai D, Tirabosco R, Jacques T, Mertens F, Szuhai K, Kindblom L, Hogendoom P, Flanagan AM. Genetic Abnormalities of the Transcription Factor T (Brachyury) in Sporadic Chordomas. Journal of molecular diagnostics 2010-Nov-30;12(6):906-906. (pubmed)
  69. Rinner B, Frohlich E, Scheipl S, Burger K, Szuhai K, Leithner A, Liegl-Atzwanger B. ESTABLISHMENT AND CHARACTERIZATION OF A NEW CHORDOMA CELL LINE. Cytometry part b-clinical cytometry 2010-Nov-30;78B(6):459-459. (pubmed)
  70. Ly LV, Bronkhorst IHG, van Beelen E, Vrolijk J, Taylor AW, Versluis M, Luyten GPM, Jager MJ. Inflammatory Cytokines in Eyes with Uveal Melanoma and Relation with Macrophage Infiltration. Investigative ophthalmology & visual science 2010-Nov-30;51(11):5445-5451. (pubmed)
  71. Weeke-Klimp A, Bax NAM, Bellu AR, Winter EM, Vrolijk J, Plantinga J, Maas S, Brinker M, Mahtab EAF, Gittenberger-de Groot AC, van Luyn MJA, Harmsen MC, Lie-Venema H. Epicardium-derived cells enhance proliferation, cellular maturation and alignment of cardiomyocytes. Journal of molecular and cellular cardiology 2010-Oct-31;49(4):606-616. (pubmed)
  72. Reijnders CMA, Waaijer CJF, Hamilton A, Buddingh EP, Dijkstra SPD, Ham J, Bakker E, Szuhai K, Karperien M, Hogendoorn PCW, Stringer SE, Bovee JVMG. No Haploinsufficiency but Loss of Heterozygosity for EXT in Multiple Osteochondromas. American journal of pathology 2010-Oct-31;177(4):1946-1957. (pubmed)
  73. Dekker P, de Lange MJ, Dirks RW, van Heemst D, Tanke HJ, Westendorp RG, Maier AB. Relation Between Maximum Replicative Capacity and Oxidative Stress-Induced Responses in Human Skin Fibroblasts In Vitro.. The journals of gerontology. series a, biological sciences and medical sciences 2010-Oct-11;:45-50. (pubmed)
  74. Shalaby A, Presneau N, Pillay N, Ye H, Idowu B, Halai D, Tirabosco R, Jacques T, Mertens F, Szuhai K, Kindblom L, Hogendoorn P, Flanagan A. In Vivo and In Vitro Implications of the Transcription Factor T (Brachyury) in Pathogenesis of Sporadic Chordomas. Journal of pathology 2010-Sep-30;222. (pubmed)
  75. Romeo S, Duim RAJ, Bridge JA, Mertens F, de Jong D, Dal Cin P, Wijers-Koster PM, Debiec-Rychter M, Sciot R, Rosenberg AE, Szuhai K, Hogendoorn PCW. Heterogeneous and Complex Rearrangements of Chromosome Arm 6q in Chondromyxoid Fibroma Delineation of Breakpoints and Analysis of Candidate Target Genes. American journal of pathology 2010-Sep-30;177(3):1365-1376. (pubmed)
  76. Willems SM, Schrage YM, Briaire-de Bruijn IH, Szuhai K, Hogendoorn PCW, Bovee JVMG. Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and Casein Kinase II inhibition as a potential treatment option. Molecular cancer 2010-Sep-23;9. (pubmed)
  77. Phillips A, Teunisse A, Lam S, Lodder K, Darley M, Emaduddin M, Wolf A, Richter J, de Lange J, Verlaan-de Vries M, Lenos K, Bohnke A, Bartel F, Blaydes JP, Jochemsen AG. HDMX-L Is Expressed from a Functional p53-responsive Promoter in the First Intron of the HDMX Gene and Participates in an Autoregulatory Feedback Loop to Control p53 Activity. Journal of biological chemistry 2010-Sep-17;285(38). (pubmed)
  78. Valentijn KM, van Driel LF, Mourik MJ, Hendriks GJ, Arends TJ, Koster AJ, Valentijn JA. Multigranular exocytosis of Weibel-Palade bodies in vascular endothelial cells. Blood 2010-Sep-09;116(10):1807-1816. (pubmed)
  79. Smeenk G, Wiegant WW, Vrolijk H, Solari AP, Pastink A, van Attikum H. The NuRD chromatin-remodeling complex regulates signaling and repair of DNA damage. Journal of cell biology 2010-Sep-06;190(5):741-749. (pubmed)
  80. Chen DF, Mauk M, Qiu XB, Liu CC, Kim JT, Ramprasad S, Ongagna S, Abrams WR, Malamud D, Corstjens PLAM, Bau HH. An integrated, self-contained microfluidic cassette for isolation, amplification, and detection of nucleic acids. Biomedical microdevices 2010-Aug-31;12(4):705-719. (pubmed)
  81. Matic I, Schimmel J, Hendriks IA, van Santen MA, van de Rijke F, van Dam H, Gnad F, Mann M, Vertegaal ACO. Site-Specific Identification of SUMO-2 Targets in Cells Reveals an Inverted SUMOylation Motif and a Hydrophobic Cluster SUMOylation Motif. Molecular cell 2010-Aug-27;39(4):641-652. (pubmed)
  82. Schimmel J, Balog CIA, Deelder AM, Drijfhout JW, Hensbergen PJ, Vertegaal ACO. Positively charged amino acids flanking a sumoylation consensus tetramer on the 110 kDa tri-snRNP component SART1 enhance sumoylation efficiency. Journal of proteomics 2010-Jun-16;73(8):1523-1534. (pubmed)
  83. Schimmel J, Balog CI, Deelder AM, Drijfhout JW, Hensbergen PJ, Vertegaal AC. Positively charged amino acids flanking a sumoylation consensus tetramer on the 110kDa tri-snRNP component SART1 enhance sumoylation efficiency.. Journal of proteomics 2010-Jun-16;73(8). (pubmed)
  84. Stepanova T, Smal I, van Haren J, Akinci U, Liu Z, Miedema M, Limpens R, van Ham M, van der Reijden M, Poot R, Grosveld F, Mommaas M, Meijering E, Galjart N. History-Dependent Catastrophes Regulate Axonal Microtubule Behavior. Current biology 2010-Jun-08;20(11):1023-1028. (pubmed)
  85. Doekhie FS, Mesker WE, Kuppen PJ, van Leeuwen GA, Morreau H, de Bock GH, Putter H, Tanke HJ, van de Velde CJ, Tollenaar RA. Detailed examination of lymph nodes improves prognostication in colorectal cancer.. International journal of cancer. journal international du cancer 2010-Jun-01;126(11). (pubmed)
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  106. Knoops K, Swett-Tapia C, van den Worm SHE, Velthuis AJWT, Koster AJ, Mommaas AM, Snijder EJ, Kikkert M. Integrity of the early secretory pathway promotes, but Is not required for, Severe Acute Respiratory Syndrome coronavirus RNA synthesis and virus-induced remodeling of endoplasmic reticulum membranes. Journal of virology 2010-Jan-15;84(2):833-846. (pubmed)
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  110. Qiu XB, Thompson JA, Chen ZY, Liu CC, Chen DF, Ramprasad S, Mauk MG, Ongagna S, Barber C, Abrams WR. Finger-actuated, self-contained immunoassay cassettes. Biomedical microdevices 2009-Dec-31;11(6):1175-1186. (pubmed)
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  112. Mesker WE, Liefers GJ, Junggeburt JMC, van Pelt GW, Alberici P, Kuppen PJK, Miranda NF, van Leeuwen KAM, Morreau H, Szuhai K. Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I-II colon cancer patients. Cellular oncology 2009-Dec-31;31(3):169-178. (pubmed)
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  116. Jonsdottir AB, Vreeswijk MPG, Wolterbeek R, Devilee P, Tanke HJ, Eyfjord JE, Szuhai K. BRCA2 heterozygosity delays cytokinesis in primary human fibroblasts. Cellular oncology 2009-Dec-31;31(3):191-201. (pubmed)
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  120. Noppe G, Dekker P, de Koning-Treurniet C, Blom J, van Heemst D, Dirks RW, Tanke HJ, Westendorp RGJ, Maier AB. Rapid Flow Cytometric Method for Measuring Senescence Associated beta-Galactosidase Activity in Human Fibroblasts. Cytometry part a 2009-Nov-30;75A(11):910-916. (pubmed)
  121. Mohseny AB, Szuhai K, Romeo S, Buddingh EP, Briaire-de Bruijn I, de Jong D, van Pel M, Cleton-Jansen AM, Hogendoorn PCW. Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss of Cdkn2. Journal of pathology 2009-Nov-30;219(3):294-305. (pubmed)
  122. McCarthy AA, Brockhauser S, Nurizzo D, Theveneau P, Mairs T, Spruce D, Guijarro M, Lesourd M, Ravelli RBG, McSweeney S. A decade of user operation on the macromolecular crystallography MAD beamline ID14-4 at the ESRF. Journal of synchrotron radiation 2009-Nov-30;16:803-812. (pubmed)
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  125. Romeo S, Szuhai K, Nishimori I, Ijszenga M, Wijers-Koster P, Taminiau AHM, Hogendoorn PCW. A balanced t(5;17) (p15;q22-23) in chondroblastoma: frequency of the re-arrangement and analysis of the candidate genes. Bmc cancer 2009-Nov-10;9. (pubmed)
  126. Hes FJ, Madan K, Rombout-Liem IS, Szuhai K, Sorensen H, van Amstel HKP, Bakker E, Visser TJ, Smit JW, Hansson K. Multiple Genomic Aberrations in a Patient With Mental Retardation and Hypogonadism: 45,X/46,X,psu dic(Y) Karyotype, Thyroid Hormone Receptor Beta (THRB) Mutation and Heterozygosity for Wilson Disease. American journal of medical genetics part a 2009-Oct-31;149A(10):2231-2235. (pubmed)
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  130. Richter J, Wolf A, Lam S, Bohnke A, Teunisse A, Lodder K, Hauptmann S, Jochemsen AG, Bartell F. Activation of p53 stimulates transcription from the MDMX P2 promoter in tumor cells. Ejc supplements 2009-Sep-30;7(2):103-103. (pubmed)
  131. Versluis F, Tomatsu I, Kehr S, Fregonese C, Tepper AWJW, Stuart MCA, Ravoo BJ, Koning RI, Kros A. Shape and Release Control of a Peptide Decorated Vesicle through pH Sensitive Orthogonal Supramolecular Interactions. Journal of the american chemical society 2009-Sep-23;131(37). (pubmed)
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  133. Kresse SH, Ohnstad HO, Paulsen EB, Bjerkehagen B, Szuhai K, Serra M, Schaefer KL, Mykiebost O, Meza-Zepeda LA. LSAMP, a Novel Candidate Tumor Suppressor Gene in Human Osteosarcomas, Identified by Array Comparative Genomic Hybridization. Genes chromosomes & cancer 2009-Aug-31;48(8):679-693. (pubmed)
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  135. Janssen BJC, Gomes L, Koning RI, Svergun DI, Koster AJ, Fritzinger DC, Vogel CW, Gros P. Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex. Embo journal 2009-Aug-19;28(16):2469-2478. (pubmed)
  136. Dorleans A, Gigant B, Ravelli RBG, Mailliet P, Mikol V, Knossow M. Variations in the colchicine-binding domain provide insight into the structural switch of tubulin. Proceedings of the national academy of sciences of the united states of ame 2009-Aug-18;106(33). (pubmed)
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  138. Willems SM, Mohseny AB, Balog C, Sewrajsing R, Briaire-de Bruijn IH, Knijnenburg J, Cleton-Jansen AM, Sciot R, Fletcher CDM, Deelder AM, Szuhai K, Hensbergen PJ, Hogendoorn PCW. Cellular/intramuscular myxoma and grade I myxofibrosarcoma are characterized by distinct genetic alterations and specific composition of their extracellular matrix. Journal of cellular and molecular medicine 2009-Jul-31;13(7):1291-1301. (pubmed)
  139. Pannu NS, Ravelli RBG, Abrahams P. The Max-Inf2/Lorentz Center workshop on New algorithms in macromolecular crystallography and electron microscopy. Acta crystallographica section d-biological crystallography 2009-Jul-31;65:623-624. (pubmed)
  140. Moskovszky L, Szuhai K, Krenacs T, Hogendoorn PCW, Szendroi M, Benassi MS, Kopper L, Fule T, Sapi Z. Genomic Instability in Giant Cell Tumor of Bone. A Study of 52 Cases Using DNA Ploidy, Relocalization FISH, and Array-CGH Analysis. Genes chromosomes & cancer 2009-Jun-30;48(6):468-479. (pubmed)
  141. Knijnenburg J, Oberstein SAJL, Frei K, Lucas T, Gijsbers ACJ, Ruivenkamp CAL, Tanke HJ, Szuhai K. A homozygous deletion of a normal variation locus in a patient with hearing loss from non-consanguineous parents. Journal of medical genetics 2009-Jun-30;46(6):412-417. (pubmed)
  142. Brooks MA, Ravelli RBG, McCarthy AA, Strub K, Cusack S. Structure of SRP14 from the Schizosaccharomyces pombe signal recognition particle. Acta crystallographica section d-biological crystallography 2009-May-31;65:421-433. (pubmed)
  143. Aten E, den Hollander N, Ruivenkamp C, Knijnenburg J, van Bokhoven H, den Dunnen J, Breuning M. Split Hand-Foot Malformation, Tetralogy of Fallot, Mental Retardation and a 1 Mb 19p Deletion-Evidence for Further Heterogeneity?. American journal of medical genetics part a 2009-May-31;149A(5):975-981. (pubmed)
  144. Szuhai K, Ijszenga M, de Jong D, Karseladze A, Tanke HJ, Hogendoorn PCW. The NFATc2 Gene Is Involved in a Novel Cloned Translocation in a Ewing Sarcoma Variant That Couples Its Function in Immunology to Oncology. Clinical cancer research 2009-Apr-01;15(7):2259-2268. (pubmed)
  145. da Costa CET, Szuhai K, van Eijk R, Hoogeboom M, Sciot R, Mertens F, Bjorgvinsdottir H, Debiec-Rychter M, de Krijger RR, Hogendoorn PCW. No Genomic Aberrations in Langerhans Cell Histiocytosis as Assessed by Diverse Molecular Technologies. Genes chromosomes & cancer 2009-Mar-31;48(3):239-249. (pubmed)
  146. Schrage YM, Hameetman L, Szuhai K, Cleton-Jansen AM, Taminiau AHM, Hogendoorn PCW, Bovee JVMG. Aberrant Heparan Sulfate Proteoglycan Localization, Despite Normal Exostosin, in Central Chondrosarcoma. American journal of pathology 2009-Mar-31;174(3):979-988. (pubmed)
  147. Nijimeijer BA, Szuhai K, Goselink HM, van Schie MLJ, van der Burg M, de Jong D, Marijt EW, Ottrnann OG, Willemze R, Falkenburg JHF. Long-term culture of primary human lymphoblastic leukemia cells in the absence of serum or hematopoietic growth factors. Experimental hematology 2009-Mar-31;37(3):376-385. (pubmed)
  148. McGeehan J, Ravelli RBG, Murray JW, Owen RL, Cipriani F, McSweeney S, Weik M, Garman EF. Colouring cryo-cooled crystals: online microspectrophotometry. Journal of synchrotron radiation 2009-Mar-31;16:163-172. (pubmed)
  149. Hambach L, Ling KW, Pool J, Aghai Z, Blokland E, Tanke HJ, Bruijn JA, Halfwerk H, Van Boven H, Wieles B. Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. Blood 2009-Mar-19;113(12):2715-2722. (pubmed)
  150. Jiang LH, Schaffitzel C, Bingel-Erlenmeyer R, Ban N, Korber P, Koning RI, de Geus DC, Plaisier JR, Abrahams JP. Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15. Journal of molecular biology 2009-Mar-13;386(5):1357-1367. (pubmed)
  151. Asp L, Kartberg F, Fernandez-Rodriguez J, Smedh M, Elsner M, Laporte F, Barcena M, Jansen KA, Valentijn JA, Koster AJ. Early Stages of Golgi Vesicle and Tubule Formation Require Diacylglycerol. Molecular biology of the cell 2009-Feb-28;20(3):780-790. (pubmed)
  152. Willems SM, Mohseny AB, Balog CI, Sewrajsting R, Briaire I, Cleton-Jansen AM, Sciot R, Fletcher CDM, Deelder AM, Szuhai K, Hensbergen PJ, Hogendoorn PCW. Intramuscular Myxoma and Grade I Myxofibrosarcoma Are Characterized by Distinct Genetic Alterations and Specific Composition of Their ECM. Modern pathology 2009-Jan-31;22. (pubmed)
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  154. Szuhai K, de Jong J, Bovee JVMG, Jennes I, Wuyts W, Wiweger M, Tanke HJ, Hogendoorn PCW. Somatic Mosaicism Is Causative in EXT1/2 Negative Multiple Osteochondroma Detected by Tiling Resolution Array-CGH. Modern pathology 2009-Jan-31;22. (pubmed)
  155. Szuhai K, de Jong J, Bovee JVMG, Jennes I, Wuyts W, Wiweger M, Tanke HJ, Hogendoorn PCW. Somatic Mosaicism Is Causative in EXT1/2 Negative Multiple Osteochondroma Detected by Tiling Resolution Array-CGH. Laboratory investigation 2009-Jan-31;89. (pubmed)
  156. Szuhai K, IJszenga M, de Jong D, Karseladze A, Tanke HJ, Hogendoorn PCW. Novel, Cloned Translocation Partner in Ewing Sarcoma Couples Its Function to Oncology. Modern pathology 2009-Jan-31;22. (pubmed)
  157. Szuhai K, IJszenga M, de Jong D, Karseladze A, Tanke HJ, Hogendoorn PCW. Novel, Cloned Translocation Partner in Ewing Sarcoma Couples Its Function to Oncology. Laboratory investigation 2009-Jan-31;89. (pubmed)
  158. Romeo S, Szuhai K, Nishimori I, Ijszenga M, Wijers-Koster P, Hogendoorn PCW. Balanced Rearrangement of Chromosome 5 and 17 in Chondroblastoma: Hints for Its Pathogenesis. Modern pathology 2009-Jan-31;22. (pubmed)
  159. Romeo S, Szuhai K, Nishimori I, Ijszenga M, Wijers-Koster P, Hogendoorn PCM. Balanced Rearrangement of Chromosome 5 and 17 in Chondroblastoma: Hints for Its Pathogenesis. Laboratory investigation 2009-Jan-31;89. (pubmed)
  160. Romeo S, Duim RAJ, Mertens F, De Jong D, Dal Cin P, Debiec-Rychter M, Sciot R, Rosenberg A, Szuhai K, Hogendoorn PCW. Balanced and Unbalanced Rearrangement of Chromosome Arm 6q in Chondromyxoid Fibroma (CMF): Delineation of Breakpoints and Analysis of Candidate Target Genes. Modern pathology 2009-Jan-31;22. (pubmed)
  161. Mohseny AB, Szuhai K, Romeo S, Buddingh EP, Bruijn IBD, de Jong D, van Pel M, Hogendoorn PCW, Cleton-Jansen AM. Homozygous Deletion of CDKN2 in Tumorigenic Mesenchymal Stem Cells: A Key Event for Osteosarcoma Genesis. Laboratory investigation 2009-Jan-31;89. (pubmed)
  162. Mohseny AB, Szuhai K, Romeo S, Budding EP, Bruyn IBD, de Jong D, van Pel M, Hogendoorn PCW, Cleton-Jansen AM. Homozygous Deletion of CDKN2 in Tumorigenic Mesenchymal Stem Cells: A Key Event for Osteosarcoma Genesis. Modern pathology 2009-Jan-31;22. (pubmed)
  163. Barcena M, Oostergetel GT, Bartelink W, Faas FGA, Verkleij A, Rottier PJM, Koster AJ, Bosch BJ. Cryo-electron tomography of mouse hepatitis virus: Insights into the structure of the coronavirion. Proceedings of the national academy of sciences of the united states of ame 2009-Jan-13;106(2):582-587. (pubmed)
  164. van Doorn R, van Kester MS, Dijkman R, Vermeer MH, Mulder AA, Szuhai K, Knijnenburg J, Boer JM, Willemze R, Tensen CP. Oncogenomic analysis of mycosis fungoides reveals major differences with Sezary syndrome. Blood 2009-Jan-01;113(1):127-136. (pubmed)
  165. Goobie S, Knijnenburg J, FitzPatrick D, Sharkey FH, Lionel AC, Marshall CR, Azam T, Shago M, Chong K, Mendoza-Londono R, den Hollander NS, Ruivenkamp C, Maher E, Tanke HJ, Szuhai K, Wintle RF, Scherer SW. Molecular and clinical characterization of de novo and familial cases with microduplication 3q29: guidelines for copy number variation case reporting. Cytogenetic and genome research 2008-Dec-31;123(1-4):65-78. (pubmed)
  166. Brockhauser S, Di Michiel M, McGeehan JE, McCarthy AA, Ravelli RBG. X-ray tomographic reconstruction of macromolecular samples. Journal of applied crystallography 2008-Dec-31;41:1057-1066. (pubmed)
  167. Raz V, Vermolen BJ, Garini Y, Onderwater JJM, Mommaas-Kienhuis MA, Koster AJ, Young IT, Tanke H, Dirks RW. The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells. Journal of cell science 2008-Dec-15;121(24):4018-4028. (pubmed)
  168. Schonfeld DL, Ravelli RBG, Mueller U, Skerra A. The 1.8-angstrom Crystal Structure of alpha(1)-Acid Glycoprotein (Orosomucoid) Solved by UV RIP Reveals the Broad Drug-Binding Activity of This Human Plasma Lipocalin. Journal of molecular biology 2008-Dec-12;384(2):393-405. (pubmed)
  169. Cormier A, Marchand M, Ravelli RBG, Knossow M, Gigant B. Structural insight into the inhibition of tubulin by vinca domain peptide ligands. Embo reports 2008-Nov-30;9(11):1101-1106. (pubmed)
  170. Agronskaia AV, Valentijn JA, van Driel LF, Schneijdenberg CTWM, Humbel BM, Henegouwen PMPVBE, Verkleij AJ, Koster AJ, Gerritsen HC. Integrated fluorescence and transmission electron microscopy. Journal of structural biology 2008-Nov-30;164(2):183-189. (pubmed)
  171. Janssen B, Gomes L, Fritzinger D, Vogel CW, Meeldijk H, Svergun D, Koning R, Koster A, Gros P. Structure of factor B in complex with cobra venom factor gives insights into convertase formation. Molecular immunology 2008-Oct-31;45(16):4096-4096. (pubmed)
  172. Booman M, Szuhai K, Rosenwald A, Hartmann E, Kluin-Nelemans HC, de Jong D, Schuuring E, Kluin PM. Genomic alterations and gene expression in primary diffuse large B-cell lymphomas of immune-privileged sites: the importance of apoptosis and immunomodulatory pathways. Journal of pathology 2008-Oct-31;216(2):209-217. (pubmed)
  173. Knoops K, Kikkert M, van den Worm SHE, Zevenhoven-Dobbe JC, van der Meer Y, Koster AJ, Mommaas AM, Snijder EJ. SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum. Plos biology 2008-Sep-30;6(9):1957-1974. (pubmed)
  174. McGeehan JE, Streeter SD, Thresh SJ, Ball N, Ravelli RBG, Kneale G. Structural analysis of the genetic switch that regulates the expression of restriction-modification genes. Nucleic acids research 2008-Aug-31;36(14):4778-4787. (pubmed)
  175. Baeumler J, Szuhai K, Falkenburg JHF, van Schiec MLJ, Ottmann OG, Nijmeijer BA. Establishment and cytogenetic characterization of a human acute lymphoblastic leukemia cell line (ALL-VG) with ETV6/ABL1 rearrangement. Cancer genetics and cytogenetics 2008-Aug-31;185(1):37-42. (pubmed)
  176. Zovko S, Abrahams JP, Koster AJ, Galjart N, Mommaas AM. Microtubule plus-end conformations and dynamics in the periphery of interphase mouse fibroblasts. Molecular biology of the cell 2008-Jul-31;19(7):3138-3146. (pubmed)
  177. Brenkman AB, de Keizer PLJ, van den Broek NJF, Jochemsen AG, Burgering BMT. Mdm2 Induces Mono-Ubiquitination of FOXO4. Plos one 2008-Jul-30;3(7). (pubmed)
  178. van Doom R, van Kester M, Dijkman R, Szuhai K, Vermeer M, Willemze R, Tensen C. Genomic profiling of mycosis fungoides reveals major differences with Sezary syndrome. Journal of investigative dermatology 2008-Apr-30;128:S66-S66. (pubmed)
  179. Corstjens PLAM, Zuiderwijk M, Tanke HJ, Schip JJVV, Ottenhoff THM, Geluk A. A user-friendly, highly sensitive assay to detect the IFN-gamma secretion by T cells. Clinical biochemistry 2008-Apr-30;41(6):440-444. (pubmed)
  180. Cheroki C, Krepischi-Santos ACV, Szuhai K, Brenner V, Kim CAE, Otto PA, Rosenberg C. Genomic imbalances associated with mullerian aplasia. Journal of medical genetics 2008-Apr-30;45(4):228-232. (pubmed)
  181. Vermeer MH, van Doorn R, Dijkman R, Mao X, Whittaker S, Vader PCVV, Gerritsen MJP, Geerts ML, Gellrich S, Soderberg O, Leuchowius KJ, Landegren U, Out-Luiting JJ, Knijnenburg J, Ijszenga M, Szuhai K, Willemze R, Tensen CP. Novel and highly recurrent chromosomal alterations in Sezary syndrome. Cancer research 2008-Apr-15;68(8):2689-2698. (pubmed)
  182. van Driel LF, Knoops K, Koster AJ, Valentijn JA. Fluorescent labeling of resin-embedded sections for correlative electron microscopy using tomography-based contrast enhancement. Journal of structural biology 2008-Mar-31;161(3):372-383. (pubmed)
  183. Valentijn KM, Valentijn JA, Jansen KA, Koster AJ. A new look at Weibel-Palade body structure in endothelial cells using electron tomography. Journal of structural biology 2008-Mar-31;161(3):447-458. (pubmed)
  184. Koning RI, Zovko S, Barcena M, Oostergetel GT, Koerten HK, Galjart N, Koster AJ, Mommaas AM. Cryo electron tomography of vitrified fibroblasts: Microtubule plus ends in situ. Journal of structural biology 2008-Mar-31;161(3):459-468. (pubmed)
  185. Medalsy I, Dgany O, Sowwan M, Cohen H, Yukashevska A, Wolf SG, Wolf A, Koster A, Almog O, Marton I, Pouny Y, Altman A, Hoseyov OS, Porath D. SP1 protein-based nanostructures and arrays. Nano letters 2008-Feb-28;8(2):473-477. (pubmed)
  186. Colson S, van Wezel GP, Craig M, Noens EEE, Nothaft H, Mommaas AM, Titgemeyer F, Joris B, Rigali S. The chitoblose-binding protein, DasA, acts as a link between chitin utilization and morphogenesis in Streptomyces coelicolor. Microbiology-sgm 2008-Feb-28;154:373-382. (pubmed)
  187. Wiesmeijer K, Krouwels IM, Tanke HJ, Dirks RW. Chromatin movement visualized with photoactivable GFP-labeled histone H4. Differentiation 2008-Jan-31;76(1):83-90. (pubmed)
  188. Corstjens PLAM, van Lieshout L, Zuiderwijk M, Kornelis D, Tanke HJ, Deelder AM, van Dam GJ. Up-converting phosphor technology-based lateral flow assay for detection of Schistosoma circulating anodic antigen in serum. Journal of clinical microbiology 2008-Jan-31;46(1):171-176. (pubmed)
  189. Hallor KH, Staaf J, Jonsson G, Heidenblad M, von Steyern FV, Bauer HCF, IJszenga M, Hogendoorn PCW, Mandahl N, Szuhai K, Mertens F. Frequent deletion of the CDKN2A locus in chordoma: analysis of chromosomal imbalances using array comparative genomic hybridisation. British journal of cancer 2008-Jan-22;98(2):434-442. (pubmed)
  190. Tanke H, Mesker W, Morreau H, Tollenaer R. New prognostic parameters in colorectal cancer. Cellular oncology 30(2):102-103. (pubmed)
  191. Smijs TGM, Mulder AA, Pavel S, Onderwater JJM, Koerten HK, Bouwstra JA. Morphological changes of the dermatophyte Trichophyton rubrum after photodynamic treatment: a scanning electron microscopy study. Medical mycology 46(4):315-325. (pubmed)
  192. Knijnenburg J, Lesnik-Oberstein S, Frei K, Gijsbers A, Ruivenkamp C, Tanke H, Szuhai K. Disease-causing homozygous deletion of a normal variation locus. Cellular oncology 30(3):261-261. (pubmed)
  193. Shir OM, Raz V, Dirks RW, Back T. Classification of cell fates with Support Vector Machine learning. Evolutionary computation, machine learning and data mining in bioinformatics, proceedings 2007-Dec-31;4447:258-269. (pubmed)
  194. Rossi S, Szuhai K, Ijszenga M, Tanke HJ, Zanatta L, Sciot R, Fletcher CDM, Tos APD, Hogencloorn PCW. EWSR1-CREB1 and EWSR1-ATF1 fusion genes in angiomatoid fibrous histiocytoma. Clinical cancer research 2007-Dec-15;13(24):7322-7328. (pubmed)
  195. Rixe O, Fojo T. Is cell death a critical end point for anticancer therapies or is cytostasis sufficient?. Clinical cancer research 2007-Dec-15;13(24):7280-7287. (pubmed)
  196. Vermeesch JR, Fiegler H, de Leeuw N, Szuhai K, Schoumans J, Ciccone R, Speleman F, Rauch A, Clayton-Smith J, Van Ravenswaaij C, Sanlaville D, Patsalis PC, Firth H, Devriendt K, Zuffardi O. Guidelines for molecular karyotyping in constitutional genetic diagnosis. European journal of human genetics 2007-Nov-30;15(11):1105-1114. (pubmed)
  197. Bimmler J, Falkenburg JHF, van Schie MLJ, Szuhai K, Pape M, Droll S, Ottmann OG, Nijmeijer B. Establishment and characterization of a tel/abl rearrangement responsible for imatinib sensitivity in ber/abl negative acute lymphoblastic leukemia. Blood 2007-Nov-16;110(11):137B-138B. (pubmed)
  198. Yakushevska AE, Lebbink MN, Geerts WJC, Spek L, van Donselaar EG, Jansen KA, Humbel BM, Post JA, Verkleij AJ, Koster AJ. STEM tomography in cell biology. Journal of structural biology 2007-Sep-30;159(3):381-391. (pubmed)
  199. Willems SM, Szuhai K, Hartgrink H, Bovee JVMG, De Schepper A, Hogendoorn PCW. CT-guided, COBRA-FISH-assisted diagnosis of well-differentiated liposarcoma (inflammatory subtype) of the retroperitoneum. Histopathology 2007-Sep-30;51(3):422-426. (pubmed)
  200. Knijnenburg J, van der Burg M, Tanke HJ, Szuhai K. Optimized amplification and fluorescent labeling of small cell samples for genomic array-CGH. Cytometry part a 2007-Aug-31;71A(8):585-591. (pubmed)
  201. Mazzeu JF, Krepischi-Santos AC, Rosenberg C, Szuhai K, Knijnenburg J, Weiss JMM, Kerkis I, Mustacchi Z, Colin G, Mombach R, Pavanello RDM, Otto PA, Vianna-Morgante AM. Chromosome abnormalities in two patients with features of autosomal dominant Robinow syndrome. American journal of medical genetics part a 2007-Aug-01;143A(15):1790-1795. (pubmed)
  202. Valentijn JA, van Weeren L, Ultee A, Koster AJ. Novel localization of Rab3D in rat intestinal goblet cells and Brunner's gland acinar cells suggests a role in early Golgi trafficking. American journal of physiology-gastrointestinal and liver physiology 2007-Jul-31;293(1):G165-G177. (pubmed)
  203. Lips EH, de Graaf EJ, Tollenaar RAEM, van Eijk R, Oosting J, Szuhai K, Karsten T, Nanya Y, Ogawa S, de Velde CJV, Eilers PHC, Van Wezel T, Morreau H. Single nucleotide polymorphism array analysis of chromosomal instability patterns discriminates rectal adenomas from carcinomas. Journal of pathology 2007-Jul-31;212(3):269-277. (pubmed)
  204. Khan S, Bijker MS, Weterings JJ, Tanke HJ, Adema GJ, van Hall T, Drijfhout JW, Melief CJM, Overkleeft HS, van der Marel GA, Filippov DV, van der Burg SH, Ossendorp F. Distinct uptake mechanisms but similar intracellular processing of two different Toll-like receptor ligand-peptide conjugates in dendritic cells. Journal of biological chemistry 2007-Jul-20;282(29):21145-21159. (pubmed)
  205. Szuhai K, IJszenga M, Knijnenburg J, Dijkstra S, de Schepper A, Tanke HJ, Hogendoorn PCW. Does parosteal liposarcoma differ from other atypical lipomatous tumors/well-differentiated liposarcomas? A molecular cytogenetic study using combined multicolor COBRA-FISH karyotyping and array-based comparative genomic hybridization. Cancer genetics and cytogenetics 2007-Jul-15;176(2):115-120. (pubmed)
  206. da Costa CET, Egeler RM, Hoogeboorn M, Szuhai K, Forsyth RG, Niesters M, de Krijger RR, Tazi A, Hogendoorn PCW, Annels NE. Differences in telomerase expression by the CD1a(+) cells in Langerhans cell histiocytosis reflect the diverse clinical presentation of the disease. Journal of pathology 2007-Jun-30;212(2):188-197. (pubmed)
  207. Vermeulen CFW, Jordanova ES, Szuhai K, Kolkman-Uljee S, Vrede MA, Peters AAW, Schtturing E, Fleuren GJ. Physical status of multiple human papillomavirus genotypes in flow-sorted cervical cancer cells. Cancer genetics and cytogenetics 2007-Jun-30;175(2):132-137. (pubmed)
  208. Sandberg Y, Szuhai K, Tielemans D, Wolvers-Tettero I, van Gastel-Mol EJ, van Dongen JJM, Langerak AW. Secondary genetic events in clonal CD8+/TCRab+ large granular lymphocyte proliferations. Haematologica-the hematology journal 2007-Jun-30;92:33-34. (pubmed)
  209. Noens EE, Mersinias V, Willemse J, Traag BA, Laing E, Chater KF, Smith CP, Koerten HK, van Wezel GP. Loss of the controlled localization of growth stage-specific cell-wall synthesis pleiotropically affects developmental gene expression in an ssgA mutant of Streptomyces coelicolor. Molecular microbiology 2007-Jun-30;64(5):1244-1259. (pubmed)
  210. Lebbink MN, Geerts WJC, van der Krift TP, Bouwhuis M, Hertzberger LO, Verkleij AJ, Koster AJ. Template matching as a tool for annotation of tomograms of stained biological structures. Journal of structural biology 2007-Jun-30;158(3):327-335. (pubmed)
  211. Hansson K, Szuhai K, Knijnenburg J, van Haeringen A, de Pater J. Interstitial deletion of 6q without phenotypic effect. American journal of medical genetics part a 2007-Jun-15;143A(12):1354-1357. (pubmed)
  212. Costa C, Annels N, Hoogeboom M, Szuhai K, Hogendoorn P, Egeler M. Investigation of potential chromosomal abnormalities in the lesional cells of Langerhans cell histiocytosis. Pediatric blood & cancer 2007-Jun-15;48(7):753-754. (pubmed)
  213. Knijnenburg J, van Haeringen A, Hansson KBM, Lankester A, Smit MJM, Belfroid RDM, Bakker E, Rosenberg C, Tanke HJ, Szuhai K. Ring chromosome formation as a novel escape mechanism in patients with inverted duplication and terminal deletion. European journal of human genetics 2007-May-31;15(5):548-555. (pubmed)
  214. van den Born E, Posthuma CC, Knoops K, Snijder EJ. An infectious recombinant equine arteritis virus expressing green fluorescent protein from its replicase gene. Journal of general virology 2007-Apr-30;88:1196-1205. (pubmed)
  215. Hoffer MJV, Hilhorst-Hofstee Y, Knijnenburg J, Hansson KB, Engelberts AC, Laan LAEM, Bakker E, Rosenberg C. A 6 Mb deletion in band 2q22 due to a complex chromosome rearrangement associated with severe psychomotor retardation, microcephaly and distinctive dysmorphic facial features. European journal of medical genetics 2007-Apr-30;50(2):149-154. (pubmed)
  216. Schrage YM, Hameetman L, Szuhai K, Cleton-Jansen AM, Taminiau AHM, Hogendoorn PCW, Bovee JVMG. EXT and its downstream targets in central chondrosarcoma (CCS). Modern pathology 2007-Mar-31;20:21A-21A. (pubmed)
  217. Schrage YM, Hameetman L, Szuhai K, Cleton-Jansen AM, Taminian AHM, Hogendoorn PCW, Bovee JVMG. EXT and its downstream targets in central chondrosarcoma (CCS). Laboratory investigation 2007-Mar-31;87:21A-21A. (pubmed)
  218. Oosting J, Lips EH, van Eijk R, Eilers PHC, Szuhai K, Wijmenga C, Morreau H, van Wezel T. High-resolution copy number analysis of paraffin-embedded archival tissue using SNP BeadArrays. Genome research 2007-Mar-31;17(3):368-376. (pubmed)
  219. Braet F, Wisse E, Bomans P, Frederik P, Geerts W, Koster A, Soon L, Ringer S. Contribution of high-resolution correlative imaging techniques in the study of the liver sieve in three-dimensions. Microscopy research and technique 2007-Mar-31;70(3):230-242. (pubmed)
  220. Kriek M, Knijnenburg J, White SJ, Rosenberg C, den Dunnen JT, van Ommen GJB, Tanke HJ, Breuning MH, Szuhai K. Diagnosis of genetic abnormalities in developmentally delayed patients: A new strategy combining MLPA and array-CGH. American journal of medical genetics part a 2007-Mar-15;143A(6):610-614. (pubmed)
  221. Hameetman L, Szuhai K, Yavas A, Knijnenburg J, van Duin M, van Dekken H, Taminiau AHM, Cleton-Jansen AM, Bovee JVMG, Hogendoorn PCW. The role of EXT1 in nonhereditary osteochondroma: identification of homozygous deletions. Journal of the national cancer institute 2007-Mar-07;99(5):396-406. (pubmed)
  222. Tolar J, Nauta AJ, Osborn MJ, Mortari AP, McElmurry RT, Bell S, Xia LL, Zhou N, Riddle M, Schroeder TM, Westendorf JJ, McIvor RS, Hogendoorn PCW, Szuhai K, Oseth L, Hirsch B, Yant SR, Kay MA, Peister A, Prockop DJ, Fibbe WE, Blazar BR. Sarcoma derived from cultured mesenchymal stem cells. Stem cells 2007-Feb-28;25(2):371-379. (pubmed)
  223. Kloth JN, Oosting J, van Wezel T, Szuhai K, Knijnenburg J, Gorter A, Kenter GG, Fleuren GJ, Jordanova ES. Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer. Bmc genomics 2007-Feb-20;8. (pubmed)
  224. Dijkman R, van Doorn R, Szuhai K, Willemze R, Vermeer MH, Tensen CP. Gene-expression profiling and array-based CGH classify CD4(+)CD56(+) hematodermic neoplasm and cutaneous myelomonocytic leukemia as distinct disease entities. Blood 2007-Feb-15;109(4):1720-1727. (pubmed)
  225. de Vries FAT, Zonneveld JBM, de Groot AJ, Koning RI, van Zeeland AA, Pastink A. Schizosaccharomyces pombe Rad22A and Rad22B have similar biochemical properties and form multimeric structures. Mutation research-fundamental and molecular mechanisms of mutagenesis 2007-Feb-03;615(1-2):143-152. (pubmed)
  226. Szuhai K, IJszenga M, Tanke HJ, Taminiau AHM, de Schepper A, van Duinen SG, Rosenberg C, Hogendoorn PCW. Detection and molecular cytogenetic characterization of a novel ring chromosome in a histological variant of Ewing sarcoma. Cancer genetics and cytogenetics 2007-Jan-01;172(1):12-22. (pubmed)
  227. Tanke HJ. Genomics and proteomics - The potential role of oral diagnostics. Oral-based diagnostics 1098:330-334. (pubmed)
  228. Ruivenkamp C, Gijsbers A, Ariyurek Y, van Haeringen A, Bijlsma E, Knijnenburg J, Szuhai K, den Dunnen J, Breuning M. SNP arrays to identify loci involved in mental retardation. Chromosome research 15:7-7. (pubmed)
  229. Mokkapati VK, Niedbala RS, Kardos K, Perez RJ, Guo M, Tanke HJ, Corstjens PLAM. Evaluation of UPlink-RSV - Prototype rapid antigen test for detection of respiratory syncytial virus infection. Oral-based diagnostics 1098:476-485. (pubmed)
  230. Mesker WE, Junggeburt JMC, Szuhai K, de Heer P, Morreau H, Tanke HJ, Tollenaar RAEM. The carcinoma-stromal ratio of colon carcinoma is an independent factor for survival compared to lymph node status and tumor stage. Cellular oncology 29(5):387-398. (pubmed)
  231. Mazzeu JF, Krepischi-Santos AC, Rosenberg C, Lourenco CM, Lezirovitz K, Szuhai K, Martelli LR, Vianna-Morgante AM. Widening the clinical spectrum of Pitt-Rogers-Danks/Wolf-Hirschhorn syndromes. Genetics and molecular biology 30(2):339-342. (pubmed)
  232. Knijnenburg J, Ruivenkamp C, Lankester A, Tanke H, Szuhai K. High resolution molecular analysis of a ring chromosome reveals unexpected alterations: Lessons for routine diagnosis. Cellular oncology 29(2):116-116. (pubmed)
  233. Jarosova M, Pospisilova H, Papajik T, Holzerova M, Balcarkova J, Plachy R, Kucerova L, Szuhai K, Indrak K. ArrayCGH and molecular cytogenetics in determination of prognostic subgroups of diffuse large B-cell lymphoma (DLBCL). Chromosome research 15:264-264. (pubmed)
  234. Costa C, Egeler M, Forsyth R, Szuhai K, Niesters M, de Krijger R, Tati A, Hogendoorn P, Annels N. Differences in telomerase expression by the CD1 a+ cells in langerhans cell histiocytosis reflects the diverse clinical presentation of the disease. Clinical immunology 123:S50-S50. (pubmed)
  235. Corstjens PLAM, Chen ZY, Zuiderwijk M, Bau HH, Abrams WR, Malamud D, Niedbala RS, Tanke HJ. Rapid assay format for multiplex detection of humoral immune responses to infectious disease pathogens (HIV, HCV, and TB). Oral-based diagnostics 1098:437-445. (pubmed)
  236. Chen ZY, Mauk MG, Wang J, Abrams WR, Corstjens PLAM, Niedbala RS, Malamud D, Bau HH. A microfluidic system for saliva-based detection of infectious diseases. Oral-based diagnostics 1098:429-436. (pubmed)
  237. Abrams WR, Barber CA, McCann K, Tong G, Chen ZY, Mauk MG, Wang J, Volkov A, Bourdelle P, Corstjensd PLAM, Zuiderwijk M, Kardos K, Li S, Tanke HJ, Niedbala RS, Malamud D, Bau H. Development of a microfluidic device for detection of pathogens in oral samples using upconverting phosphor technology (UPT). Oral-based diagnostics 1098:375-388. (pubmed)
  238. van Dieren JM, Wink JC, Vissers KJ, van Marion R, Hoogmans MMCP, Dinjens WNM, Schouten WR, Tanke HJ, Szuhai K, Kuipers EJ, van der Woude CJ, Dekken H. Chromosomal and microsatellite instability of adenocarcinomas and dysplastic lesions (DALM) in ulcerative colitis. Diagnostic molecular pathology 2006-Dec-31;15(4):216-222. (pubmed)
  239. Sandberg Y, Dezentje VO, Szuhai K, van Houte AJ, Tielemans D, Wolvers-Tettero ILM, van Dongen JJM, van der Griend R, Langerak AW. Clonal T- and natural killer-cell large granular lymphocyte proliferations in a single patient established by array-based comparative genomic hybridization analysis. Leukemia 2006-Dec-31;20(12):2212-2214. (pubmed)
  240. Keijser S, de Keizer RJW, Prins FA, Tanke HJ, van Rooijen N, Vrensen GFJM, Jager MJ. A new model for limbal transplantation using E-GFP for follow-up of transplant survival. Experimental eye research 2006-Nov-30;83(5):1188-1195. (pubmed)
  241. Schaffitzel C, Oswald M, Berger I, Ishikawa T, Abrahams JP, Koerten HK, Koning RI, Ban N. Structure of the E-coli signal recognition particle bound to a translating ribosome. Nature 2006-Nov-23;444(7118):503-506. (pubmed)
  242. van den Worm SHE, Koning RI, Warmenhoven HJ, Koerten HK, van Duin J. Cryo electron microscopy reconstructions of the Leviviridae unveil the densest icosahedral RNA packing possible. Journal of molecular biology 2006-Nov-03;363(4):558-565. (pubmed)
  243. Fatouros DG, Groenink HWM, de Graaff AM, van Aelst AC, Koerten HK, Bouwstra JA. Visualization studies of human skin in vitro/in vivo under the influence of an electrical field. European journal of pharmaceutical sciences 2006-Oct-31;29(2):160-170. (pubmed)
  244. Raz V, Carlotti F, Vermolen BJ, van der Poel E, Sloos WCR, Knaan-Shanzer S, de Vries AAF, Hoeben RC, Young IT, Tanke HJ, Garini Y, Dirks RW. Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells. Journal of cell science 2006-Oct-15;119(20):4247-4256. (pubmed)
  245. Rigali S, Nothaft H, Noens EEE, Schlicht M, Colson S, Muller M, Joris B, Koerten HK, Hopwood DA, Titgemeyer F, van Wezel GP. The sugar phosphotransferase system of Streptomyces coelicolor is regulated by the GntR-family regulator DasR and links N-acetylglucosamine metabolism to the control of development. Molecular microbiology 2006-Sep-30;61(5):1237-1251. (pubmed)
  246. Oberstein SAJL, Kriek M, White SJ, Kalf ME, Szuhai K, den Dunnen JT, Breuning MH, Hennekam RCM. Peters plus syndrome is caused by mutations in B3GALTL, a putative glycosyltransferase. American journal of human genetics 2006-Sep-30;79(3):562-566. (pubmed)
  247. Kriek M, Szuhai K, Kant SG, White SJ, Dauwerse H, Fiegler H, Carter NP, Knijnenburg J, den Dunnen JT, Tanke HJ, Breuning MH, Rosenberg C. A complex rearrangement on chromosome 22 affecting both homologues; haplo-insufficiency of the Cat eye syndrome region may have no clinical relevance. Human genetics 2006-Aug-31;120(1):77-84. (pubmed)
  248. Nijhof JGW, Braun KM, Giangreco A, van Pelt C, Kawamoto H, Boyd RL, Willemze R, Mullenders LHF, Watt FM, de Gruijl FR, van Ewijk W. The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells. Development 2006-Aug-01;133(15):3027-3037. (pubmed)
  249. Rozeman LB, Szuhai K, Schrage YM, Rosenberg C, Tanke HJ, Taminiau AHM, Cleton-Jansen AM, Bovee JVMG, Hogendoorn PCW. Array-comparative genomic hybridization of central chondrosarcoma - Identification of ribosomal protein S6 and cyclin-dependent kinase 4 as candidate target genes for genomic aberrations. Cancer 2006-Jul-15;107(2):380-388. (pubmed)
  250. Snijder EJ, van der Meer Y, Zevenhoven-Dobbe J, Onderwater JJM, van der Meulen J, Koerten HK, Mommaas AM. Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex. Journal of virology 2006-Jun-30;80(12):5927-5940. (pubmed)
  251. Dirks RW, Tanke HJ. Styryl molecules light-up RNAs. Chemistry & biology 2006-Jun-30;13(6):559-560. (pubmed)
  252. Cheroki C, Krepischi-Santos AC, Rosenberg C, Jehee F, Mingroni-Netto RC, Pavanello I, Zanforlin S, Kim CA, Bagnoli VR, Mendonca BB, Szuhai K, Otto PA. Report of a del22q11 in a patient with Mayer-Rokitansky-Kuster-Hauser (MRKH) anomaly and exclusion of WNT-4, RAR-gamma, and RXR-alpha as major genes determining MRKH anomaly in a study of 25 affected women. American journal of medical genetics part a 2006-Jun-15;140A(12):1339-1342. (pubmed)
  253. van Dekken H, Wink JC, Vissers KJ, van Marion R, Koppert LB, Tilanus HW, Siersema PD, Tanke HJ, Szuhai K, Hop WCJ. Genomic analysis of early adenocarcinoma of the esophagus or gastroesophageal junction: Tumor progression is associated with alteration of 1q and 8p sequences. Genes chromosomes & cancer 2006-May-31;45(5):516-525. (pubmed)
  254. Skakun VV, Novikov EG, Apanasovich VV, Tanke HJ, Deelder AM, Mayboroda OA. Initial guesses generation for fluorescence intensity distribution analysis. European biophysics journal with biophysics letters 2006-May-31;35(5):410-423. (pubmed)
  255. Mazza P, Noens EE, Schirner K, Grantcharova N, Mommaas AM, Koerten HK, Muth G, Flardh K, Van Wezel GP, Wohlleben W. MreB of Streptomyces coelicolor is not essential for vegetative growth but is required for the integrity of aerial hyphae and spores. Molecular microbiology 2006-May-31;60(4):838-852. (pubmed)
  256. Postma R, Van Marion R, Van Duin M, Vissers KJ, Wink JC, Schroder FH, Tanke HJ, Szuhai K, Van Der Kwast TH, Van Dekken H. Array-based genomic analysis of screen-detected Gleason score 6 and 7 prostatic adenocarcinomas. Anticancer research 2006-Apr-30;26(2A):1193-1200. (pubmed)
  257. Doekhie FS, Kuppen PJK, Peeters KCMJ, Mesker WE, van Soest RA, Morreau H, de Velde CJH, Tanke HJ, Tollenaar RAEM. Prognostic relevance of occult tumour cells in lymph nodes in colorectal cancer. Ejso 2006-Apr-30;32(3):253-258. (pubmed)
  258. Dirks RW, Tanke HJ. Advances in fluorescent tracking of nucleic acids in living cells. Biotechniques 2006-Apr-30;40(4):489-496. (pubmed)
  259. van Dekken H, Vissers K, Tilanus HW, Kuo WL, Tanke HJ, Rosenberg C, IJszenga M, Szuhai K. Genomic array and expression analysis of frequent high-level amplifications in adenocarcinomas of the gastro-esophageal junction. Cancer genetics and cytogenetics 2006-Apr-15;166(2):157-162. (pubmed)
  260. Szuhai K, IJszenga M, Tanke HJ, Rosenberg C, Hogendoorn PCW. Molecular cytogenetic characterization of four previously established and two newly established Ewing sarcoma cell lines. Cancer genetics and cytogenetics 2006-Apr-15;166(2):173-179. (pubmed)
  261. Willems SM, Debiec-Rychter M, Szuhai K, Hogendoorn PCW, Sciot R. Local recurrence of myxofibrosarcoma is associated with increase in tumour grade and cytogenetic aberrations, suggesting a multistep tumour progression model. Modern pathology 2006-Mar-31;19(3):407-416. (pubmed)
  262. Pelikan DM, Kanhai HH, De Groot-Swings GM, Mesker WE, Tanke HJ, Scherjon SA. Fetomaternal hemorrhage in relation to chorionic villus sampling revisited. Prenatal diagnosis 2006-Mar-31;26(3):201-205. (pubmed)
  263. De Schepper S, Boucneau JMA, Westbroek W, Mommaas M, Onderwater J, Messiaen L, Naeyaert JMAD, Lambert JLW. Neurofibromatosis type 1 protein and amyloid precursor protein interact in normal human melanocytes and colocalize with melanosomes. Journal of investigative dermatology 2006-Mar-31;126(3):653-659. (pubmed)
  264. Courtens W, Wuyts W, Poot M, Szuhai K, Wauters J, Reyniers E, Eleveld M, Diaz G, Nothen MM, Parvari R. Hypoparathyroidism-retardation-dysmorphism syndrome in a girl: A new variant not caused by a TBCE mutation - Clinical report and review. American journal of medical genetics part a 2006-Mar-15;140A(6):611-617. (pubmed)
  265. Cardoso J, Molenaar L, de Menezes RX, van Leerdam M, Rosenberg C, Moslein G, Sampson J, Morreau H, Boer JM, Fodde R. Chromosomal instability in MYH- and APC-mutant adenomatous polyps. Cancer research 2006-Mar-01;66(5):2514-2519. (pubmed)
  266. Rosenberg C, Knijnenburg J, Bakker E, Vianna-Morgante AM, Fiegler H, Carter NP, Bijlsma EK, van Haeringen A, Szuhai K, Tanke HJ. Array-CGH detection of micro rearrangements in mentally retarded individuals: clinical significance of imbalances present both in affected children and normal parents. Journal of medical genetics 2006-Feb-28;43(2):180-186. (pubmed)
  267. Kriek M, White SJ, Szuhai K, Knijnenburg J, van Ommen GJB, den Dunnen JT, Breuning MH. Copy number variation in regions flanked (or unflanked) by duplicons among patients with developmental delay and/or congenital malformations; detection of reciprocal and partial Williams-Beuren duplications. European journal of human genetics 2006-Feb-28;14(2):180-189. (pubmed)
  268. Van der Heiden K, Groenendijk BCW, Hierck BP, Hogers B, Koerten HK, Mommaas AM, Gittenberger-de Groot AC, Poelmann RE. Monocilia on chicken embryonic endocardium in low shear stress areas. Developmental dynamics 2006-Jan-31;235(1):19-28. (pubmed)
  269. Dijkman R, Tensen CP, Jordanova ES, Knijnenburg J, Hoefnagel JJ, Mulder AA, Rosenberg C, Raap AK, Willemze R, Szuhai KR, Vermeer MH. Array-based comparative genomic hybridization analysis reveals recurrent chromosomal alterations and prognostic parameters in primary cutaneous large B-cell lymphoma. Journal of clinical oncology 2006-Jan-10;24(2):296-305. (pubmed)
  270. Wang J, Chen ZY, Corstjens PLAM, Mauk MG, Bau HH. A disposable microfluidic cassette for DNA amplification and detection. Lab on a chip 6(1):46-53. (pubmed)
  271. Varela MC, Krepischi-Santos ACV, Paz JA, Knijnenburg J, Szuhai K, Rosenberg C, Koiffmann CP. A 17q21.31 microdeletion encompassing the MAPT gene in a mentally impaired patient. Cytogenetic and genome research 114(1):89-92. (pubmed)
  272. Stewenius Y, Tanke HJ, Wiegant J, Gisselsson D. Cryptic terminal chromosome rearrangements in colorectal carcinoma cell lines detected by subtelomeric FISH analysis. Cytogenetic and genome research 114(3-4):257-262. (pubmed)
  273. Raap AK, Tanke HJ. COmbined Binary RAtio fluorescence in situ hybridiziation (COBRA-FISH): development and applications. Cytogenetic and genome research 114(3-4):222-226. (pubmed)
  274. Mesker WE, Vrolijk H, Sloos WCR, Tollenaar RAEM, Tanke HJ. Detection of tumor cells in bone marrow, peripheral blood and lymph nodes by automated imaging devices. Cellular oncology 28(4):141-150. (pubmed)
  275. Krepischi-Santos ACV, Vianna-Morgante AM, Jehee FS, Passos-Bueno MR, Knijnenburg J, Szuhai K, Sloos W, Mazzeu JF, Kok F, Cheroki C, Otto PA, Mingroni-Netto RC, Varela M, Koiffmann C, Kim CA, Bertola DR, Pearson PL, Rosenberg C. Whole-genome array-CGH screening in undiagnosed syndromic patients: old syndromes revisited and new alterations. Cytogenetic and genome research 115(3-4):254-261. (pubmed)
  276. Jehee FS, Rosenberg C, Krepischi-Santos AC, Kok F, Knijnenburg J, Froyen G, Vianna-Morgante AM, Opitz JM, Passos-Bueno MR. An Xq22.3 duplication detected by comparative genomic hybridization microarray (Array-CGH) defines a new locus (FGS5) for FG syndrome. American journal of medical genetics part a 2005-Dec-15;139A(3):221-226. (pubmed)
  277. Noens EEE, Mersinias V, Traag BA, Smith CP, Koerten HK, van Wezel GP. SsgA-like proteins determine the fate of peptidoglycan during sporulation of Streptomyces coelicolor. Molecular microbiology 2005-Nov-30;58(4):929-944. (pubmed)
  278. Piette A, Derouanx A, Gerkens P, Noens EEE, Mazzucchelli G, Vion S, Koerten HK, Titgemeyer F, De Pauw E, Leprince P, van Wezel GP, Galleni M, Rigali SB. From dormant to germinating spores of Streptomyces coelicolor A3(2): New perspectives from the crp null mutant. Journal of proteome research 2005-Oct-31;4(5):1699-1708. (pubmed)
  279. Doekhie FS, Peeters KCMJ, Kuppen PJK, Mesker WE, Tanke HJ, Morreau H, van de Velde CJH, Tollenaar RAEM. The feasibility and reliability of sentinel node mapping in colorectal cancer. Ejso 2005-Oct-31;31(8):854-862. (pubmed)
  280. Cramers P, Atanasova P, Vrolijk H, Darroudi F, van Zeeland AA, Huiskamp R, Mullenders LHF, Kleinjans JCS. Pre-exposure to low doses: Modulation of x-ray-induced DNA damage and repair?. Radiation research 2005-Oct-31;164(4):383-390. (pubmed)
  281. Akhmanova A, Mausset-Bonnefont AL, van Cappellen W, Keijzer N, Hoogenraad CC, Stepanova T, Drabek K, van der Wees J, Mommaas M, Onderwater J, van der Meulen H, Tanenbaum ME, Medema RH, Hoogerbrugge J, Vreeburg J, Uringa EJ, Grootegoed JA, Grosveld F, Galjart N. The microtubule plus-end-tracking protein CLIP-170 associates with the spermatid manchette and is essential for spermatogenesis. Genes & development 2005-Oct-15;19(20):2501-2515. (pubmed)
  282. Doekhie TS, Mesker WE, van Krieken JHJM, Kok NFM, Hartgrink HH, Kranenbarg EK, Putter H, Kuppen PJK, Tanke HJ, Tollenaar RAEM, van de Velde CJH. Clinical relevance of occult tumor cells in lymph nodes from gastric cancer patients. American journal of surgical pathology 2005-Sep-30;29(9):1135-1144. (pubmed)
  283. Helip-Wooley A, Westbroek W, Dorward H, Mommaas M, Boissy RE, Gahl WA, Huizing M. Association of the Hermansky-Pudlak syndrome type-3 protein with clathrin. Bmc cell biology 2005-Sep-13;6. (pubmed)
  284. Krouwels IM, Wiesmeijer K, Abraham TE, Molenaar C, Verwoerd NP, Tanke HJ, Dirks RW. A glue for heterochromatin maintenance: stable SUV39H1 binding to heterochromatin is reinforced by the SET domain. Journal of cell biology 2005-Aug-15;170(4):537-549. (pubmed)
  285. Kalayda GV, Zhang GF, Abraham T, Tanke HJ, Reedijk J. Application of fluorescence microscopy for investigation of cellular distribution of dinuclear platinum anticancer drugs. Journal of medicinal chemistry 2005-Aug-11;48(16):5191-5202. (pubmed)
  286. Morgan ME, Flierman R, van Duivenvoorde LM, Witteveen HJ, van Ewijk W, van Laar JA, de Vries RRP, Toes REM. Effective treatment of collagen-induced arthritis by adoptive transfer of CD25+ regulatory T cells. Arthritis and rheumatism 2005-Jul-31;52(7):2212-2221. (pubmed)
  287. Dumortier H, van Mierlo GJD, Egan D, van Ewijk W, Toes REM, Offringa R, Melief CJM. Antigen presentation by an immature myeloid dendritic cell line does not cause CTL deletion in vivo, but generates CD8(+) central memory-like T cells that can be rescued for full effector function. Journal of immunology 2005-Jul-15;175(2):855-863. (pubmed)
  288. Tong M, Jacobi CE, van de Rijke FM, Kuijper S, van de Werken S, Lowary TL, Hokke CH, Appelmelk BJ, Nagelkerke NJD, Tanke HJ, van Gijlswijkh RPM, Veuskens J, Kolk AHJ, Raap AK. A multiplexed and miniaturized serological tuberculosis assay identifies antigens that discriminate maximally between TB and non-TB sera. Journal of immunological methods 2005-Jun-30;301(1-2):154-163. (pubmed)
  289. Ouwens DM, Boer C, Fodor M, de Galan P, Heine RJ, Maassen JA, Diamant M. Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats. Diabetologia 2005-Jun-30;48(6):1229-1237. (pubmed)
  290. Kuipers HF, Biesta PJ, Groothuis TA, Neefjes JJ, Mommaas AM, van den Elsen PJ. Statins affect cell-surface expression of major histocompatibility complex class II molecules by disrupting cholesterol-containing Microdomains. Human immunology 2005-Jun-30;66(6):653-665. (pubmed)
  291. Groenendijk BCW, Hierck BP, Vrolijk J, Baiker M, Pourquie MJBM, Gittenberger-de Groot AC, Poelmann RE. Changes in shear stress-related gene expression after experimentally altered venous return in the chicken embryo. Circulation research 2005-Jun-24;96(12):1291-1298. (pubmed)
  292. de Pauw ESD, Roelofs H, Zwinderman A, van Houwelingen JC, Fibbe WE, de Knijff P, Pearson PL, Tanke HJ. Studying the biological and technical sources of variation in telomere length of individual chromosomes. Cytometry part a 2005-May-31;65A(1):35-39. (pubmed)
  293. Kalayda GV, Jansen BAJ, Wielaard P, Tanke HJ, Reedijk J. Dinuclear platinum anticancer complexes with fluorescent N,N '-bis(aminoalkyl)-1,4-diaminoanthraquinones: cellular processing in two cisplatin-resistant cell lines reflects the differences in their resistance profiles. Journal of biological inorganic chemistry 2005-May-31;10(3):305-315. (pubmed)
  294. Aigouy L, Mortier M, Gierak J, Bourhis E, De Wilde Y, Corstjens P, Tanke HJ. Field distribution on metallic and dielectric nanoparticles observed with a fluorescent near-field optical probe. Journal of applied physics 2005-May-15;97(10). (pubmed)
  295. Verdijk P, Dijkman R, Plasmeijer EI, Mulder AA, Zoutman WH, Mommaas AM, Tensen CP. A lack of Birbeck granules in Langerhans cells is associated with a naturally occurring point mutation in the human Langerin gene. Journal of investigative dermatology 2005-Apr-30;124(4):714-717. (pubmed)
  296. Verdijk P, Dijkman R, Plasmeijer EI, Mulder AA, Zoutman WH, Mieke Mommaas A, Tensen CP. A lack of Birbeck granules in Langerhans cells is associated with a naturally occurring point mutation in the human Langerin gene.. The journal of investigative dermatology 2005-Apr-30;124(4). (pubmed)
  297. Rosenberg C, Knijnenburg J, Chauffaille M, Brunoni D, Catelani AL, Sloos W, Szuhai K, Tanke HJ. Array CGH detection of a cryptic deletion in a complex chromosome rearrangement. Human genetics 2005-Apr-30;116(5):390-394. (pubmed)
  298. Frei K, Ramsebner R, Lucas T, Hamader G, Szuhai K, Weipoltshammer K, Baumgartner WD, Wachtler FJ, Kirschhofer K. GJB2 mutations in hearing impairment: Identification of a broad clinical spectrum for improved genetic counseling. Laryngoscope 2005-Mar-31;115(3):461-465. (pubmed)
  299. Tanke HJ, Dirks RW, Raap T. FISH and immunocytochemistry: towards visualising single target molecules in living cells. Current opinion in biotechnology 2005-Feb-28;16(1):49-54. (pubmed)
  300. Guikema JEJ, Fenton JAL, de Boer C, Kleiverda K, Brink AATP, Raap AK, Estrov Z, Schuuring E, Kluin PM. Complex biallelic IGH rearrangements in IgM-expressing Z-138 cell line: Involvement of downstream immunoglobulin class switch recombination. Genes chromosomes & cancer 2005-Feb-28;42(2):164-169. (pubmed)
  301. Knijnenburg J, Szuhai K, Giltay J, Molenaar L, Sloos W, Poot M, Tanke HJ, Rosenberg C. Insights from genomic microarrays into structural chromosome rearrangements. American journal of medical genetics part a 2005-Jan-01;132A(1):36-40. (pubmed)
  302. van Wezel T, Lombaerts M, van Roon EH, Philippo K, Baelde HJ, Szuhai K, Cornelisse CJ, Cleton-Jansen AM. Expression analysis of candidate breast tumour suppressor genes on chromosome 16q. Breast cancer research 7(6):R998-R1004. (pubmed)
  303. Knijnenburg J, van der Burg M, Nilsson P, van Amstel HKP, Tanke H, Szuhai K. Rapid detection of genomic imbalances using micro-arrays consisting of pooled BACs covering all human chromosome arms. Nucleic acids research 33(18). (pubmed)
  304. Hazelbag HM, Szuhai K, Tanke HJ, Rosenberg C, Hogendoorn PCW. Primary synovial sarcoma of the heart: a cytogenetic and molecular genetic analysis combining RT-PCR and COBRA-FISH of a case with a complex karyotype. Modern pathology 2004-Nov-30;17(11):1434-1439. (pubmed)
  305. Bivas-Benita M, Oudshoorn M, Romeijn S, van Meijgaarden K, Koerten H, van der Meulen H, Lambert G, Ottenhoff T, Benita S, Junginger H, Borchard G. Cationic submicron emulsions for pulmonary DNA immunization. Journal of controlled release 2004-Nov-05;100(1):145-155. (pubmed)
  306. Westbroek W, Lambert J, De Schepper S, Kleta R, Van den Bossche K, Seabra MC, Huizing M, Mommaas M, Naeyaert JM. Rab27b is up-regulated in human Griscelli syndrome type II melanocytes and linked to the actin cytoskeleton via exon F-myosin va transcripts. Pigment cell research 2004-Oct-31;17(5):498-505. (pubmed)
  307. Ferber MJ, Eilers P, Schuuring E, Fenton JAL, Fleuren GJ, Kenter G, Szuhai K, Smith DI, Raap AK, Brink AATP. Positioning of cervical carcinoma and Burkitt lymphoma translocation breakpoints with respect to the human papillomavirus integration cluster in FRA8C at 8q24.13. Cancer genetics and cytogenetics 2004-Oct-01;154(1):1-9. (pubmed)
  308. Mesker WE, Torrenga H, Sloos WCR, Vrolijk H, Tollenaar RAEM, de Bruin PC, van Diest PJ, Tanke HJ. Supervised automated microscopy increases sensitivity and efficiency of detection of sentinel node micrometastases in patients with breast cancer. Journal of clinical pathology 2004-Sep-30;57(9):960-964. (pubmed)
  309. Mussmann R, Engstler M, Gerrits H, Kieft R, Toaldo CB, Onderwater J, Koerten H, van Luenen HGAM, Borst P. Factors affecting the level and localization of the transferrin receptor in Trypanosoma brucei. Journal of biological chemistry 2004-Sep-24;279(39):40690-40698. (pubmed)
  310. Wiegant J, Brouwer K, Bezrookove V, Smits S, Raap AK, Bout A, Tanke HJ. Molecular cytogenetic characterization by combined COBRA-FISH and fiber-FISH: application to PER.C6 (R) cells. Biotechniques 2004-Aug-31;37(2):188-+. (pubmed)
  311. Szuhai K, Knijnenburg J, Ijszenga M, Tanke HJ, Baatenburg RJ, de Jong RJB, Dekker PBD, Rosenberg C, Hogendoorn PCW. Multicolor fluorescence in situ hybridization analysis of a synovial sarcoma of the larynx with a t(X;18)(p11.2;q11.2) and trisomy-2 and trisomy-8. Cancer genetics and cytogenetics 2004-Aug-31;153(1):48-52. (pubmed)
  312. Lindeman JHN, Hanemaaijer R, Mulder A, Dijkstra S, Szuhai K, Bromme D, Verheijen JH, Hogendoorn PCW. Cathepsin K is the principal protease in giant cell tumor of bone. American journal of pathology 2004-Aug-31;165(2):593-600. (pubmed)
  313. Raap AK, van der Burg MJM, Knijnenburg J, Meershoek E, Rosenberg C, Gray JW, Wiegant J, Hodgson JG, Tanke HJ. Array comparative genomic hybridization with cyanin cis-platinum-labeled DNAs. Biotechniques 2004-Jul-31;37(1):130-134. (pubmed)
  314. Kuzniacka A, Mertens F, Strombeck B, Wiegant J, Mandahl N. Combined binary ratio labeling fluorescence in situ hybridization analysis of chordoma. Cancer genetics and cytogenetics 2004-Jun-30;151(2):178-181. (pubmed)
  315. Kalayda GV, Jansen BAJ, Molenaar C, Wielaard P, Tanke HJ, Reedijk J. Dinuclear platinum complexes with N,N '-bis(aminoalkyl)-1,4-diaminoanthraquinones as linking ligands. Part II. Cellular processing in A2780 cisplatin-resistant human ovarian carcinoma cells: new insights into the mechanism of resistance. Journal of biological inorganic chemistry 2004-Jun-30;9(4):414-422. (pubmed)
  316. Jansen BAJ, Wielaard P, Kalayda GV, Ferrari M, Molenaar C, Tanke HJ, Brouwer J, Reedijk J. Dinuclear platinum complexes with N,N '-bis(aminoalkyl)-1,4-diaminoanthraquinones as linking ligands. Part I. Synthesis, cytotoxicity, and cellular studies in A2780 human ovarian carcinoma cells. Journal of biological inorganic chemistry 2004-Jun-30;9(4):403-413. (pubmed)
  317. Gorski MM, Romeijn RJ, Eeken JCJ, de Jong AWM, van Veen BL, Szuhai K, Mullenders LH, Ferro W, Pastink A. Disruption of Drosophila Rad50 causes pupal lethality, the accumulation of DNA double-strand breaks and the induction of apoptosis in third instar larvae. Dna repair 2004-Jun-03;3(6):603-615. (pubmed)
  318. Rieger B, Molenaar C, Dirks RW, Van Vliet LJ. Alignment of the cell nucleus from labeled proteins only for 4D in vivo imaging. Microscopy research and technique 2004-Jun-01;64(2):142-150. (pubmed)
  319. van Nieuwpoort F, Smit NPM, Kolb R, van der Meulen H, Koerten H, Pavel S. Tyrosine-induced melanogenesis shows differences in morphologic and melanogenic preferences of melanosomes from light and dark skin types. Journal of investigative dermatology 2004-May-31;122(5):1251-1255. (pubmed)
  320. Vellinga J, Rabelink MJWE, Cramer SJ, van den Wollenberg DJM, Van der Meulen H, Leppard KN, Fallaux FJ, Hoeben RC. Spacers increase the accessibility of peptide ligands linked to the carboxyl terminus of adenovirus minor capsid protein IX. Journal of virology 2004-Apr-30;78(7):3470-3479. (pubmed)
  321. Molenaar C, Abdulle A, Gena A, Tanke HJ, Dirks RW. Poly(A)(+) RNAs roam the cell nucleus and pass through speckle domains in transcriptionally active and inactive cells. Journal of cell biology 2004-Apr-26;165(2):191-202. (pubmed)
  322. van Rossenberg SMW, van Keulen ACI, Drijfhout JW, Vasto S, Koerten HK, Spies F, van 't Noordende JM, van Berkel THC, Biessen EAL. Stable polyplexes based on arginine-containing oligopeptides for in vivo gene delivery. Gene therapy 2004-Mar-31;11(5):457-464. (pubmed)
  323. Plaisier JR, Koning RI, Koerten HK, van Heel M, Abrahams JP. TYSON: Robust searching, sorting, and selecting of single particles in electron micrographs. Journal of structural biology 2004-Feb-28;145(1-2):76-83. (pubmed)
  324. Baas AF, Kuipers J, van der Wel NN, Batlle E, Koerten HK, Peters PJ, Clevers HC. Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. Cell 2004-Feb-06;116(3):457-466. (pubmed)
  325. Verdijk P, van Veelen PA, de Ru AH, Hensbergen PJ, Mizuno K, Koerten HK, Koning F, Tensen CP, Mommaas AM. Morphological changes during dendritic cell maturation correlate with cofilin activation and translocation to the cell membrane. European journal of immunology 2004-Jan-31;34(1):156-164. (pubmed)
  326. Mayboroda OA, van Remoortere A, Tanke HJ, Hokke CH, Deelder AM. A new approach for fluorescence correlation spectroscopy (FCS) based immunoassays. Journal of biotechnology 2004-Jan-22;107(2):185-192. (pubmed)
  327. Smit N, Vicanova J, Cramers P, Vrolijk H, Pavel S. The combined effects of extracts containing carotenoids and vitamins E and C on growth and pigmentation of cultured human melanocytes. Skin pharmacology & physiology 17(5):238-245. (pubmed)
  328. Cardoso J, Molenaar L, de Menezes RX, Rosenberg C, Morreau H, Moslein G, Fodde R, Boer JM. Genomic profiling by DNA amplification of laser capture microdissected tissues and array CGH. Nucleic acids research 32(19). (pubmed)
  329. Molenaar C, Wiesmeijer K, Verwoerd NP, Khazen S, Eils R, Tanke HJ, Dirks RW. Visualizing telomere dynamics in living mammalian cells using PNA probes. Embo journal 2003-Dec-15;22(24):6631-6641. (pubmed)
  330. Bezrookove V, Smits R, Moeslein G, Fodde R, Tanke HJ, Raap AK, Darroudi F. Premature chromosome condensation revisited: A novel chemical approach permits efficient cytogenetic analysis of cancers. Genes chromosomes & cancer 2003-Oct-31;38(2):177-186. (pubmed)
  331. Ferber MJ, Thorland EC, Brink AA, Rapp AK, Phillips LA, McGovern R, Gostout BS, Cheung TH, Chung TKH, Fu WY, Smith DI. Preferential integration of human papillomavirus type 18 near the c-myc locus in cervical carcinoma. Oncogene 2003-Oct-16;22(46):7233-7242. (pubmed)
  332. Mesker WE, Doekhie FS, Vrolijk H, Keyzer R, Sloos WCR, Morreau H, O'Kelly PS, de Bock GH, Tollenaar RAEM, Tanke HJ. Automated analysis of multiple sections for the detection of occult cells in lymph nodes. Clinical cancer research 2003-Oct-15;9(13):4826-4834. (pubmed)
  333. van de Rijke FM, Heetebrij RJ, Talman EG, Tanke HJ, Raap AK. Fluorescence properties, thermal duplex stability, and kinetics of formation of cyanin platinum DNAs. Analytical biochemistry 2003-Oct-01;321(1):71-78. (pubmed)
  334. Beverstock GC, Bezrookove V, Mollevanger P, van de Kamp JJP, Pearson P, Kouwenberg JM, Rosenberg C. Multiple supernumerary ring chromosomes of different origin in a patient: A clinical report and review of the literature. American journal of medical genetics part a 2003-Oct-01;122A(2):168-173. (pubmed)
  335. Engels H, Ehrbrecht A, Zahn S, Bosse K, Vrolijk H, White S, Kalscheuer V, Hoovers JMN, Schwanitz G, Propping P, Tanke HJ, Wiegant J, Raap AK. Comprehensive analysis of human subtelomeres with combined binary ratio labelling fluorescence in situ hybridisation. European journal of human genetics 2003-Sep-30;11(9):643-651. (pubmed)
  336. Koning R, van den Worm S, Plaisier JR, van Duin J, Abrahams JP, Koerten H. Visualization by cryo-electron microscopy of genomic RNA that binds to the protein capsid inside bacteriophage MS2. Journal of molecular biology 2003-Sep-12;332(2):415-422. (pubmed)
  337. Zhang YH, Leliveld SR, Kooistra K, Molenaar C, Rohn JL, Tanke HJ, Abrahams JP, Noteborn MHM. Recombinant Apoptin multimers kill tumor cells but are nontoxic and epitope-shielded in a normal-cell-specific fashion. Experimental cell research 2003-Sep-10;289(1):36-46. (pubmed)
  338. van Koningsbruggen S, de Haard H, de Kievit P, Dirks RW, van Remoortere A, Groot AJ, van Engelen BGM, den Dunnen JT, Verrips CT, Frants RR, van der Maarel SM. Llama-derived phage display antibodies in the dissection of the human disease oculopharyngeal muscular dystrophy. Journal of immunological methods 2003-Aug-31;279(1-2):149-161. (pubmed)
  339. Vrolijk H, Sloos W, Mesker W, Franken P, Fodde R, Morreau H, Tanke H. Automated acquisition of stained tissue microarrays for high-throughput evaluation of molecular targets. Journal of molecular diagnostics 2003-Aug-31;5(3):160-167. (pubmed)
  340. Plaisier JR, Koning RI, Koerten HK, van Roon AM, Thomassen EAJ, Kuil ME, Hendrix J, Broennimann C, Pannu NS, Abrahams JP. Area detectors in structural biology. Nuclear instruments & methods in physics research section a-accelerators sp 2003-Aug-21;509(1-3):274-282. (pubmed)
  341. Leliveld SR, Dame RT, Mommaas MA, Koerten HK, Wyman C, Danen-van Oorschot AAAM, Rohn JL, Noteborn MHM, Abrahams JP. Apoptin protein multimers form distinct higher-order nucleoprotein complexes with DNA. Nucleic acids research 2003-Aug-15;31(16):4805-4813. (pubmed)
  342. Keijser BJF, Noens EEE, Kraal B, Koerten HK, van Wezel GP. The Streptomyces coelicolor ssgB gene is required for early stages of sporulation. Fems microbiology letters 2003-Aug-08;225(1):59-67. (pubmed)
  343. Zuiderwijk M, Tanke HJ, Niedbala RS, Corstjens PLAM. An amplification-free hybridization-based DNA assay to detect Streptococcus pneumoniae utilizing the up-converting phosphor technology. Clinical biochemistry 2003-Jul-31;36(5):401-403. (pubmed)
  344. Storlazzi CT, Mertens F, Domanski H, Fletcher CDM, Wiegant J, Mandahl N. Ring chromosomes and low-grade gene amplification in an atypical lipomatous tumor with minimal nuclear atypia. International journal of oncology 2003-Jul-31;23(1):67-71. (pubmed)
  345. Pelikan DMV, Mesker WE, Scherjon SA, Kanhai HHH, Tanke HJ. Improvement of the Kleihauer-Betke test by automated detection of fetal erythrocytes in maternal blood. Cytometry part b-clinical cytometry 2003-Jul-31;54B(1):1-9. (pubmed)
  346. Heetebrij RJ, Talman EG, Von Velzen MA, Von Gijlswijk RPM, Snoeijers SS, Schalk M, Wiegant J, Von der Rijke F, Kerkhoven RM, Raap AK, Tanke HJ, Reedijk J, Houthoff HJ. Platinum(II)-based coordination compounds as nucleic acid labeling reagents: Synthesis, reactivity, and applications in hybridization assays. Chembiochem 2003-Jul-07;4(7):573-583. (pubmed)
  347. van Dekken H, Alers JC, Damen IAAJ, Vissers KJ, Krijtenburg PJ, Hoedemaeker RF, Wildhagen MF, Hop WCJ, van der Kwast TH, Tanke HJ, Schroder FH. Genetic evaluation of localized prostate cancer in a cohort of forty patients: Gain of distal 8q discriminates between progressors and nonprogressors. Laboratory investigation 2003-Jun-30;83(6):789-796. (pubmed)
  348. Hagedoorn R, Joseph R, Kasanmoentalib S, Eilers P, Killian J, Raap AK. Chemical RNA Labeling without 3 ' end bias using fluorescent cis-platin compounds. Biotechniques 2003-May-31;34(5):974-+. (pubmed)
  349. Pavel S, Smit NPM, van der Meulen H, Kolb RM, de Groot AJL, van der Velden PA, Gruis NA, Bergman W. Homozygous germline mutation of CDKN2A/p16 and glucose-6-phosphate dehydrogenase deficiency in a multiple melanoma case. Melanoma research 2003-Apr-30;13(2):171-178. (pubmed)
  350. Paulsson K, Lassen C, Kuric N, Billstrom R, Fioretos T, Tanke HJ, Johansson B. MYC is not overexpressed in a case of chronic myelomonocytic leukemia with MYC-containing double minutes. Leukemia 2003-Apr-30;17(4):813-815. (pubmed)
  351. van Hemert MJ, Deelder AM, Molenaar C, Steensma HY, van Heusden GPH. Self-association of the spindle pole body-related intermediate filament protein Fin1p and its phosphorylation-dependent interaction with 14-3-3 proteins in yeast. Journal of biological chemistry 2003-Apr-25;278(17):15049-15055. (pubmed)
  352. Westbroek W, Lambert J, Bahadoran P, Busca R, Herteleer MC, Smit N, Mommaas M, Ballotti R, Naeyaert JM. Interactions of human myosin Va isoforms, endogenously expressed in human melanocytes, are tightly regulated by the tail domain. Journal of investigative dermatology 2003-Mar-31;120(3):465-475. (pubmed)
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  354. Corstjens PLAM, Zuiderwijk M, Nilsson M, Feindt H, Niedbala RS, Tanke HJ. Lateral-flow and up-converting phosphor reporters to detect single-stranded nucleic acids in a sandwich-hybridization assay. Analytical biochemistry 2003-Jan-15;312(2):191-200. (pubmed)
  355. Roelofs H, de Pauw ESD, Zwinderman AH, Opdam SM, Willemze R, Tanke HJ, Fibbe WE. Homeostasis of telomere length rather than telomere shortening after allogeneic peripheral blood stem cell transplantation. Blood 2003-Jan-01;101(1):358-362. (pubmed)
  356. Paulsson K, Fioretos T, Strombeck B, Mauritzson N, Tanke HJ, Johansson B. Trisomy 8 as the sole chromosomal aberration in myelocytic malignancies: a multicolor and locus-specific fluorescence in situ hybridization study. Cancer genetics and cytogenetics 2003-Jan-01;140(1):66-69. (pubmed)
  357. Wiesmeijer K, Molenaar C, Bekeer IMLA, Tanke HJ, Dirks RW. Mobile foci of Sp100 do not contain PML: PML bodies are immobile but PML and Sp100 proteins are not. Journal of structural biology 2002-Dec-31;140(1-3):180-188. (pubmed)
  358. Wiegant J, van Hall T, van der Burg M, Colombo M, Tanke HJ, Offringa R, Rosenberg C. Application of multicolor fluorescence in situ hybridization analysis for detection of cross-contamination and in vitro progression in commonly used murine tumor cell lines. Cancer genetics and cytogenetics 2002-Dec-31;139(2):126-132. (pubmed)
  359. Barbouti A, Johansson B, Hoglund M, Mauritzson N, Strombeck B, Nilsson PG, Tanke HJ, Hagemeijer A, Mitelman F, Fioretos T. Multicolor COBRA-FISH analysis of chronic myeloid leukemia reveals novel cryptic balanced translocations during disease progression. Genes chromosomes & cancer 2002-Oct-31;35(2):127-137. (pubmed)
  360. Van Gijlswijk RPM, Talman EG, Peekel I, Bloem J, Van Velzen MA, Heetebrij RJ, Tanke HJ. Use of horseradish peroxidase- and fluorescein-modified cisplatin derivatives for simultaneous labeling of nucleic acids and proteins. Clinical chemistry 2002-Aug-31;48(8):1352-1359. (pubmed)
  361. Rosenberg C, Geelen E, Ijszenga MJ, Pearson P, Tanke HJ, Dinjens WNM, van Dekken H. Spectrum of genetic changes in gastro-esophageal cancer cell lines determined by an integrated molecular cytogenetic approach. Cancer genetics and cytogenetics 2002-May-31;135(1):35-41. (pubmed)
  362. Brink AATP, Wiegant JCAG, Szuhai K, Tanke HJ, Kenter GG, Fleuren GJ, Schuuring E, Raap AK. Simultaneous mapping of human papillomavirus integration sites and molecular karyotyping in short-term cultures of cervical carcinomas by using 49-color combined binary ratio labeling fluorescence in situ hybridization. Cancer genetics and cytogenetics 2002-Apr-15;134(2):145-150. (pubmed)
  363. de Pauw ESD, Otto SA, Wijnen JT, Vossen JM, van Weel MH, Tanke HJ, Miedema F, Willemze R, Roelofs H, Fibbe WE. Long-term follow-up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic stem cell exhaustion. British journal of haematology 2002-Feb-28;116(2):491-496. (pubmed)
  364. Hattinger CM, Jochemsen AG, Tanke HJ, Dirks RW. Induction of p21 mRNA synthesis after short-wavelength UV light visualized in individual cells by RNA FISH. Journal of histochemistry & cytochemistry 2002-Jan-31;50(1):81-89. (pubmed)
  365. Snaar SP, Verdijk P, Tanke HJ, Dirks RW. Kinetics of HCMV immediate early mRNA expression in stably transfected fibroblasts. Journal of cell science 2002-Jan-15;115(2):321-328. (pubmed)
  366. Darroudi F, Bezrookove V, Fomina J, Mesker WE, Wiegant JCAG, Raap AK, Tanke HJ. Insights into the sites of X ray and neutron induced chromosomal aberrations in human lymphocytes using COBRA-MFISH. Radiation protection dosimetry 99(1-4):189-192. (pubmed)
  367. Szuhai K, Sandhaus E, Kolkman-Uljee SM, Lemaitre M, Truffert JC, Dirks RW, Tanke HJ, Fleuren GJ, Schuuring E, Raap AK. A novel strategy for human papillomavirus detection and genotyping with SybrGreen and molecular beacon polymerase chain reaction. American journal of pathology 2001-Nov-30;159(5):1651-1660. (pubmed)
  368. Corstjens P, Zuiderwijk M, Brink A, Li S, Feindt H, Neidbala RS, Tanke H. Use of up-converting phosphor reporters in lateral-flow assays to detect specific nucleic acid sequences: A rapid, sensitive DNA test to identify human papillomavirus type 16 infection. Clinical chemistry 2001-Oct-31;47(10):1885-1893. (pubmed)
  369. van de Rijke F, Zijlmans H, Li S, Vail T, Raap AK, Niedbala RS, Tanke HJ. Up-converting phosphor reporters for nucleic acid microarrays. Nature biotechnology 2001-Mar-31;19(3):273-276. (pubmed)
  370. Johansson B, Axelsson P, Billstrom R, Strombeck B, Arheden K, Olofsson T, Cervin A, Adriansson M, Tanke HJ, Mitelman F, Fioretos T. Isodicentric 7p, idic(7)(q11.2), in acute myeloid leukemia associated with older age and favorable response to induction chemotherapy: A new clinical entity?. Genes chromosomes & cancer 2001-Mar-31;30(3):261-266. (pubmed)
  371. Jin C, Martins C, Jin YS, Wiegant L, Wennerberg L, Dictor M, Gisselsson D, Strombeck B, Fonseca I, Mitelman F, Tanke HJ, Hoglund M, Mertens F. Characterization of chromosome aberrations in salivary gland tumors by FISH, including multicolor COBRA-FISH. Genes chromosomes & cancer 2001-Feb-28;30(2):161-167. (pubmed)
  372. Alers JC, Krijtenburg PJ, Vis AN, Hoedemaeker RF, Wildhagen MF, Hop WCJ, van der Kwast TH, Schroder FH, Tanke HJ, van Dekken H. Molecular cytogenetic analysis of prostatic adenocarcinomas from screening studies - Early cancers may contain aggressive genetic features. American journal of pathology 2001-Feb-28;158(2):399-406. (pubmed)
  373. Szuhai K, van den Ouweland JM, Dirks RW, Lemaitre M, Truffert JC, Janssen GM, Tanke HJ, Holme E, Maassen JA, Raap AK. Simultaneous A8344G heteroplasmy and mitochondrial DNA copy number quantification in Myoclonus Epilepsy and Ragged-Red Fibers (MERRF) Syndrome by a multiplex Molecular Beacon based real-time fluorescence PCR. Nucleic acids research 2001-Feb-01;29(3). (pubmed)
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  375. Molenaar C, Teuben JM, Heetebrij RJ, Tanke HJ, Reedijk J. New insights in the cellular processing of platinum antitumor compounds, using fluorophore-labeled platinum complexes and digital fluorescence microscopy. Journal of biological inorganic chemistry 2000-Oct-31;5(5):655-665. (pubmed)
  376. Snaar S, Wiesmeijer K, Jochemsen AG, Tanke HJ, Dirks RW. Mutational analysis of fibrillarin and its mobility in living human cells. Journal of cell biology 2000-Oct-30;151(3):653-662. (pubmed)
  377. Biessen EAL, Valentijn ARPM, De Vrueh RLA, Van de Bilt E, Sliedregt LAJM, Prince P, Bijsterbosch MK, Van Boom JH, Van der Marel GA, Abrahams PJ, Van Berkel TJC. Novel hepatotrophic prodrugs of the antiviral nucleoside 9-(2-phosphonylmethoxyethyl)adenine with improved pharmacokinetics and antiviral activity. Faseb journal 2000-Sep-30;14(12):1784-1792. (pubmed)
  378. van de Rijke FM, Florijn RJ, Tanke HJ, Raap AK. DNA fiber-FISH staining mechanism. Journal of histochemistry & cytochemistry 2000-Jun-30;48(6):743-745. (pubmed)
  379. Wiegant J, Bezrookove V, Rosenberg C, Tanke HJ, Raap AK, Zhang HG, Bittner M, Trent JM, Meltzer P. Differentially painting human chromosome arms with combined binary ratio-labeling fluorescence in situ hybridization. Genome research 2000-Jun-30;10(6):861-865. (pubmed)
  380. Alers JC, Rochat J, Krijtenburg PJ, Hop WCJ, Kranse R, Rosenberg C, Tanke HJ, Schroder FH, van Dekken H. Identification of genetic markers for prostatic cancer progression. Laboratory investigation 2000-Jun-30;80(6):931-942. (pubmed)
  381. Szuhai K, Bezrookove V, Wiegant J, Vrolijk J, Dirks RW, Rosenberg C, Raap AK, Tanke HJ. Simultaneous molecular karyotyping and mapping of viral DNA integration sites by 25-color COBRA-FISH. Genes chromosomes & cancer 2000-May-31;28(1):92-97. (pubmed)
  382. Bezrookove V, Hansson K, van der Burg M, van der Smagt JJ, Hilhorst-Hofstee Y, Wiegant J, Beverstock GC, Raap AK, Tanke H, Breuning MH, Rosenberg C. Individuals with abnormal phenotype and normal G-banding karyotype: improvement and limitations in the diagnosis by the use of 24-colour FISH. Human genetics 2000-Apr-30;106(4):392-398. (pubmed)
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  385. Wiegant JCAG, van Gijlswijk RPM, Heetebrij RJ, Bezrookove V, Raap AK, Tanke HJ. ULS: a versatile method of labeling nucleic acids for FISH based on a monofunctional reaction of cisplatin derivatives with guanine moieties. Cytogenetics and cell genetics 87(1-2):47-52. (pubmed)
  386. Oosterwijk JC, Knepfle CFHM, Mesker WE, Vrolijk H, Sloos WCR, Pattenier H, Ravkin I, van Ommen GJB, Kanhai HHH, Tanke HJ. Strategies for rare-event detection: An approach for automated fetal cell detection in maternal blood. American journal of human genetics 1998-Dec-31;63(6):1783-1792. (pubmed)
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