Electron Microscopy Facility
Equipment
The electron microscopy facility houses in total four transmission, scanning and cryo electron microscopes, all necessary accompanying specimen preparation equipment, and computing for image analysis and visualization.
The Talos Arctica cryo-electron microscope is used for single particle analysis and tomography to determine the structure of proteins, viruses, extracellular vesicles and cellular organelles.
A Tecnai 12 transmission electron microscope is available for imaging of chemically fixed, plastic embedded, stained thin sections, to image the morphology of cells, organoids and tissues.
The Gemini scanning electron microscope can image samples using 'conventional' SEM for surface representations, and with the Gatan 3View installed for block face SEM for 3D imaging of tissues.
For sectioning of chemically fixed, heavy metal stained and plastic embedded materials into 50 to 100 nm sections for TEM.
For (cryo-) sectioning of chemically fixed, heavy metal stained and plastic embedded or sucrose embedded materials into 50 to 100 nm sections for TEM, CLEM and antibody-gold labeling.
For automated serial sectioning of chemically fixed, heavy metal stained and plastic embedded materials into 50 to 100 nm sections for array tomography SEM.
Glow discharging device for making (grid) surfaces hydrophilic. 
Carbon coating device for generation of electron conducting surfaces as support of samples on electron microscopy grids.
Grid plunger for vitrification of thin (<500 nm) samples by plunge-freezing suspensions for cryo-EM.
High pressure freezer for vitrification of thick (<10 um) samples in water at high pressure (2000 bar) for high-quality structural preservation in TEM.
Device for Automatic Freeze Substitution of samples vitrified using high-pressure freezing.
Critical point dryer for preparation of specimens for “conventional” SEM. 
Sputter coater used for metal (Pt/Au) coating to make a conductive surface of specimens for “conventional” SEM.
Microwave for speeding up the plastic embedding of chemically fixed and stained samples.