Rheumatoid arthritis does not develop overnight. By the time a diagnosis is made, inflammation has often been present for some time, even though it is not yet visible on the outside. Ideally patients at risk for RA are recognized and treated in this at-risk phase in order to prevent progression to clinically apparent disease. New research shows that this approach can improve outcomes in ACPA-negative patients and may even prevent rheumatoid arthritis.
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