From gene to structure, accelerating protein research

Protein Facility

The LUMC Protein Facility is a dedicated core facility providing state-of-the-art infrastructure, expert training, and scientific support for recombinant protein production, biochemical and biophysical characterization, and structural biology.
We offer comprehensive services ranging from hands-on training to full-service project support, covering the entire workflow from gene to structure. Our services are available to both LUMC/academic researchers and industry collaborators.

Services

Our service pipeline guides you from initial construct design to protein production and downstream analysis, providing the expertise and infrastructure needed to support your research efficiently and effectively.

Our workflow includes:

  1. Construct design and cloning
  2. Protein expression
  3. Protein purification
  4. Biophysical characterization
  5. Molecular interaction studies
  6. Structural biology

Equipment

The Protein Facility is equipped with state-of-the-art infrastructure for the heterologous expression and purification of recombinant proteins. In addition, a broad range of biophysical techniques is available to assess protein quality and to perform functional and interaction studies, including activity measurements and binding analyses.

Pricing

We operate under a hybrid funding model, with institutional support and user fees covering operational costs. Our charges are designed to ensure fair access to state-of-the-art protein research services while maintaining sustainability.

For details, please contact proteinfacility@lumc.nl

First time users

  If you are a first time user, please contact us at proteinfacility@lumc.nl.

About us

The LUMC Protein Facility aims to empower internal and external researchers by providing state-of-the-art infrastructure and expertise for protein production, purification, and characterization. Our mission is to streamline your workflow "from gene to structure" by guiding projects through every stage. By offering both comprehensive full-service support and hands-on equipment training, the facility serves as a collaborative hub that accelerates research, advances drug discovery, and helps scientists uncover the underlying mechanisms of human disease.

Contact

Email: proteinfacility@lumc.nl

Phone number: 68701 (internal)

Address

Protein Facility
LUMC - Building 2, office S-01-36
Einthovenweg 20
2333 ZC Leiden
The Netherlands