Facilitating pre-clinical research with SPF rodents

Central Animal Facility

The Central Animal Facility (Proefdiercentrum; PDC) offers support to research projects with SPF animals, immunodeficient animals or other. These include basic husbandry and care, breeding, education and (practical) training in laboratory animal science, generation of genetically modified animals through the Transgenesis Facility Leiden (TFL), cryo-banking and rederivation services, pathology service, imaging, behavioural assays and all regular non-GLP preclinical screening assays.

Some specials are used in Isocages, they are used for Malaria, Schistosomas and Covid research for example.

Besides this, we offer the transfer or export/import of animals, MAP/RAP testing and assistance with experiments.

Mouse in research situation
Liquid Nitrogen storage of embryo's and sperm at the LUMC

Services

The Central Animal Facility helps researchers with animal husbandry and care, breeding animals, and generation of genetically altered animals. In addition, the DPC together with the TFL provides full service for the cryo storage of your favorite lines as embryos and/or sperm. Moreover, we offer non-GLP clinical testing, pathology and hematology services, and biotechnical support for animal experiments.

We also provide education and training so researchers have the knowledge and competence to work with animals in a responsible, ethical and safe way. 

Equipment

The PDC provides a wide variety of equipment for researchers and the best veterinary care.

Specialized equipment for in vivo research is available through associated facilities and participating research groups in the following fields:

  • autoclaves
  • fumigation
  • vaporizers
  • microscopes
  • anesthesia
  • behavior set up
  • imaging
  • neurophysiology
  • day-night chambers
  • metabolic cages

Pricing

Quality assurance

We are currently working under Good Research Practices (GRP) and ARRIVE guidelines for animal research,and Regulatory compliance via guidelines of the NVWA and EU ETS 2010/63.

In 2027 the PDC will be ISO9001 accredited. Furthermore, we offer non-GLP preclinical testing.  

All technical equipment is maintained annually, the animal facility is state-of-the-art and well equipped.

Individual ventilated cages in an airflow cabinet
Mouse in research situation

About us

The LUMC animal facility has been at the forefront of animal research for decades. We have built up extensive expertise in animal husbandry and complex experimental procedures.

This professional highly trained setting means that we are able to facilitate animal experiments where necessary, while continuously working to reduce, refine and replace animal experiments. All staffing, including associated department offer highly skilled and competent staffing.  

Contact

PDC Bedrijfsbureau

PDC-Bedrijfsbureau@lumc.nl
+31 (0)71 526 96988

LUMC Reseach building
Einthovenweg 20
2333 ZC Leiden

Open Mon-Fri 8.00-16.30h  

Photos by Els van der Hoek