Professor in Experimental Vascular Medicine
Prof. dr. P.H.A. (Paulus) Quax
Area(s) of expertise:
Bloodvessels
Bloodvessels
&width=400&height=400)
Introduction
I am Professor of Experimental Vascular Medicine at Leiden University Medical Center (LUMC).
After my study Molecular Biology in Nijmegen (1979-1986). I received my doctorate in 1991 at the University of Leiden.
My research focuses on the cellular and molecular mechanisms of vascular remodeling in both health and disease, including atherosclerosis, restenosis, bypass graft failure, neovascularization, and wound healing. By integrating preclinical and clinical studies, my group aims to unravel pathophysiological processes in the vessel wall and develop novel therapeutic strategies to beneficially modulate vascular remodeling, with the ultimate goal of translating mechanistic insights into innovative clinical interventions. Next to my role in research I am involved in teaching, e.g. as coordinator of the scientific internship program of the master Medical School of the LUMC, and have several roles in the research organization with the LUMC, such as vice-chair of the LUMC Research Counsel and scientific coordinator of the Leiden Cariovascular Medicine LUMC theme of innovation .
After my study Molecular Biology in Nijmegen (1979-1986). I received my doctorate in 1991 at the University of Leiden.
My research focuses on the cellular and molecular mechanisms of vascular remodeling in both health and disease, including atherosclerosis, restenosis, bypass graft failure, neovascularization, and wound healing. By integrating preclinical and clinical studies, my group aims to unravel pathophysiological processes in the vessel wall and develop novel therapeutic strategies to beneficially modulate vascular remodeling, with the ultimate goal of translating mechanistic insights into innovative clinical interventions. Next to my role in research I am involved in teaching, e.g. as coordinator of the scientific internship program of the master Medical School of the LUMC, and have several roles in the research organization with the LUMC, such as vice-chair of the LUMC Research Counsel and scientific coordinator of the Leiden Cariovascular Medicine LUMC theme of innovation .
Scientific research
My research is dedicated to understanding the mechanisms of vascular remodeling in both beneficial and pathological contexts. I focus on the role of the vessel wall, endothelial function, inflammation, and immune interactions in processes such as atherosclerosis, restenosis, and bypass graft failure, as well as neovascularization and wound healing. By closely integrating preclinical and clinical studies, my goal is to translate mechanistic insights into novel therapeutic strategies that improve vascular health and patient outcomes.
This research fit closely within the Leiden CardioVascular Medicin theme of the LUMC
Honors and awards:
2015 Fellow of the American Heart Foundation (FAHA), Council on Basic
Cardiovascular Sciences.
2007 – 2011 LIFT Professor-ship TNO, positioned at the LUMC
2002 – now Established Investigator, Netherlands Heart Foundation
1998 – 2002 Career Development Awardee, Netherlands Heart Foundation
This research fit closely within the Leiden CardioVascular Medicin theme of the LUMC
Honors and awards:
2015 Fellow of the American Heart Foundation (FAHA), Council on Basic
Cardiovascular Sciences.
2007 – 2011 LIFT Professor-ship TNO, positioned at the LUMC
2002 – now Established Investigator, Netherlands Heart Foundation
1998 – 2002 Career Development Awardee, Netherlands Heart Foundation
