Image guided surgery

Key publications

  1. Van den Berg N.S., Buckle T., KleinJan G.H., van der Poel H.G., van Leeuwen F.W.B. Multispectral fluorescence imaging during robot-assisted laparoscopic sentinel node biopsy, a first step towards a fluorescence-based anatomical roadmap. Eur. Urol. 2017, 72, 110-117. 
  2. Boogerd L.S.F., Hoogstins C.E.S., Schaap D.P., Kusters M., Handgraaf H.J.M., van der Valk M.J.M., Hilling D.E., Holman F.A., Peeters K., Mieog J.S.D., van de Velde C.J.H., Farina-Sarasqueta A., van Lijnschoten I., Framery B., Pelegrin A., Gutowski M., Nienhuijs S.W., de Hingh I., Nieuwenhuijzen G.A.P., Rutten H.J.T., Cailler F., Burggraaf J., Vahrmeijer A.L. Safety and effectiveness of SGM-101, a fluorescent antibody targeting carcinoembryonic antigen, for intraoperative detection of colorectal cancer: a dose-escalation pilot study. Lancet Gastroenterol Hepatol. Mar 2018;3(3):181-191.
  3. Burggraaf J. , Kamerling I.M.C., Gordon P.B., Schrier L., de Kam M.L., Kales A.J., Bendiksen R., Indrevoll B., Bjerke  R.M.  , Moestue   S.A.  , Yazdanfar S., Langers   A.M.J.  , Swaerd-Nordmo   M.  , Torheim   G.     , Warren M.V., Morreau H., Dalsgaard G.T., Voorneveld P.W., Buckle T., van Leeuwen F.W.B., Ødegårdstuen L.I., Healey A., Hardwick J.C.H. Detection of colorectal polyps using an intravenously administered fluorescent peptide targeted against c-Met. Nature Med. 2015, 21, 955-61. 
  4. Hoogstins C.E.S., Boogerd L.S.F., Sibinga Mulder B.G., Mieog J.S.D., Swijnenburg R.J., van de Velde C.J.H., Farina Sarasqueta A., Bonsing B.A., Framery B., Pelegrin A., Gutowski M., Cailler F., Burggraaf J., Vahrmeijer A.L. Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent. Ann Surg Oncol. Oct 2018;25(11):3350-3357.
  5. Hoogstins C.E., Tummers Q.R., Gaarenstroom K.N., de Kroon C.D., Trimbos J.B., Bosse T., Smit V.T., Vuyk J., van de Velde C.J., Cohen A.F., Low P.S., Burggraaf J., Vahrmeijer A.L. A Novel Tumor-Specific Agent for Intraoperative Near-Infrared Fluorescence Imaging: A Translational Study in Healthy Volunteers and Patients with Ovarian Cancer. Clin Cancer Res. Jun 15 2016;22(12):2929-2938.
  6. Hyun H., Park M.H., Owens E.A., Wada H., Henary M., Handgraaf H.J., Vahrmeijer A.L., Frangioni J.V., Choi H.S.Structure-inherent targeting of near-infrared fluorophores for parathyroid and thyroid gland imaging. Nat Med. Feb 2015;21(2):192-197.
  7. KleinJan G.H., van den Berg N.S., Brouwer O.R., Acar C., Wit E.M., Vegt E., Valdés Olmos R.A., van Leeuwen F.W.B., van der Poel H.G. Optimization of fluorescence guidance during robot-assisted laparoscopic sentinel node biopsy procedures for prostate cancer. Eur. Urol. 2014, 66, 991-8.
  8. Van Leeuwen F.W.B., Winter A., van der Poel H., Eiber M., Suardi N., Graefen M., Wawroschek F., Maurer T. “Image-guided surgery techniques for lymphatic metastases in prostate cancer” Nat. Rev. Urol. 2019 in press.
  9. Maurer T., van Leeuwen P.J., Wit E.M.K., van der Poel H.G., van Leeuwen F.W.B. Robot-assisted laparoscopic surgery using DROP-IN radioguidance - first-in-human translation. Eur. J. Nucl. Med. Mol. Imaging 2019, 46, 49-53.
  10. Vahrmeijer AL, Hutteman M, van der Vorst JR, van de Velde CJ, Frangioni JV. Image-guided cancer surgery using near-infrared fluorescence. Nat Rev Clin Oncol. Sep 2013;10(9):507-518.