Light Microscopy Facility

Equipment

We offer a wide range of microscopes to match different sample types and research needs.

Depending on your requirements, we can image fast or at high resolution, on live or fixed samples, and on thin or thick specimens.

Our systems support imaging of slides, multi-well plates, and dishes. We also provide long-term live-cell imaging using controlled environmental conditions.

For large-scale experiments, high-throughput systems can automatically scan multi-well plates and generate both qualitative and quantitative data.

Depending on your requirements, we can image fast or at high resolution, on live or fixed samples, and on thin or thick specimens.

Our systems support imaging of slides, multi-well plates, and dishes. We also provide long-term live-cell imaging using controlled environmental conditions.

For large-scale experiments, high-throughput systems can automatically scan multi-well plates and generate both qualitative and quantitative data.

Slide scanners are available for fast, large-scale imaging of many samples.

Are you unsure which equipment you need? Contact us at l.voortman@lumc.nl with your questions.

Widefield microscopes

Applications: Fast imaging but with lower resolution than confocal.

Example samples: Fixed cells; FISH; Immunofluorescence; Live cell imaging with strong signals  

Confocal microscopes

Applications: 3D z-stacks; Multi-channel fluorescence; Tile scan

Example samples: 2D cell culture; Tissue sections; Fixed immunostained samples; Live cells expressing  

Spinning disc confocal microscopes

Applications: Faster than scanning confocal; Live-cell imaging with reduced phototoxicity; Large field of view or z-stacks

Example samples: Live cell dynamics; Organoids; Fast biological processes; 3D cell cultures

Slidescanner microscopes

Applications: Automated imaging of slides (tissue sections); Large area scanning

Example samples: Histological sections; Whole slide imaging; Clinical pathology samples

Lightsheet microscopes

Applications: Rapid 3D imaging; Imaging of large fixed samples

Example samples: Cleared tissue samples; Embryos; Organoids; Whole small organisms