The Leiden Genome Technology Center acquired the 10x Genomics Chromium X platform in January 2022
The market leader for single-cell studies, the Chromium controller series is an advanced microfluidics platform that can process up to 16 samples at once, generating up to 1 million barcoded single-cells per run. More information about the technology can be found on 10xgenomics.com.
Single-cell 3’ solution High-throughput single-cell expression measurements that enable the discovery of gene expression dynamics and molecular profiling of individual cell types
Single cell V(D)J solution A comprehensive, scalable tool for profiling full-length paired V(D)J transcripts from hundreds to millions of lymphocytes. This new solution enables the assembly of full-length V(D)J sequences on a cell-by-cell basis, providing high-resolution insights into the adaptive immune system.
Single cell ATAC-seq solution Reveal the epigenomic landscape and analyse chromatin accessibility cell-by-cell to decipher gene regulatory mechanisms.
Single cell multiome solution Explore combined gene expression and chromatin accessibility data from the same cell to uncover gene regulatory programs
The Nadia Instrument is a fully automated system to encapsulate samples. This microfluidic droplet-based platform can be used for single-cell capture. It’s possible to encapsulate up to 8 samples, in parallel, in under 20 mins. Over 50,000 single cells can be captured per cartridge in a run. More information about the technology can be found on dolomite-bio.com.
Encapsulation of cells in agarose
Formulatrix MANTIS Liquid Handler
The MANTIS dispenses any reagent efficiently and reproducibly regardless of volume, viscosity, temperature, or concentration. It accurately dispenses a range of volumes from 0.1ul – 200ul in formats from 6-well to 1536-well plates. Different wells can receive different volumes and different reagents, which allows for a variety of applications including reaction miniaturization, plate dispensing, and plate normalization. More information about the technology can be found on formulatrix.com.
Assay Development and Design of Experiment
Next-Generation Sequencing – Library Preparation
Polymerase Chain-reaction Workflows – Real-time and Digital