With the Gravitation programme, the Dutch Government encourages excellent research in the Netherlands. The programme is for scientific consortia that have the potential to rank among the world's best in their field.
A consortium is a collaboration between the best researchers in the Netherlands in a discipline or in several disciplines. The intended scientific research programme is innovative, makes a substantial contribution at the highest global level, and has the potential to realise international breakthroughs. The programme makes a contribution to the realisation of the Dutch National Research Agenda. Furthermore, the consortia make a substantial contribution to the training of talented researchers.
The Gravitation programme started in 2012 and runs until 2026.
For the 2012, 2013 and 2016 funding rounds, budgets of 167, 153, and 113 million euros were available respectively, for obligations of up to ten years' duration.
(Source: NWO website)
NWO Gravitation Grant - 2017
Title: Netherlands Organ-on-Chip Initiative (NOCI)
Main applicant: Prof. dr. C.L. Mummery
Department of Anatomy and Embryology (link)
Co-applicants: Prof. M.D. Ferrari (Leiden University Medical Center) in collaboration with Prof S. Kushner (Erasmus Medical Centre), Prof. J.C. Clevers (Hubrecht Institute), Prof. P.M. Sarro (Delft University of Technology), Prof. A. van den Berg (University of Twente), Prof. C. Wijmenga (University Medical Center Grongingen)
Host institution: LUMC
Amount awarded: EUR 18.800.000
For many common diseases in humans, there are no good laboratory models to study the condition. Using stem cells from patients we will develop "disease-specific miniature organs on microchips" to investigate precise mechanisms underlying diseases of the heart, brain and intestine and the effects of intestinal bacteria and drugs on these processes. Simulating and studying the smallest functional building blocks of these tissues in “organs-on-a-chip” will allow us to identify new drug targets. Linking organ chips together will also allow us to investigate how diseased organs and intestinal bacteria influence each other. With this approach we hope to learn more about how certain diseases arise and how they might be treated.
NWO Gravitation Grant - 2013
Title: The Institute for Chemical Immunology (ICI)
Main applicant: Prof. dr. J.J.C. Neefjes
Department of Chemical Immunology (link)
Co-applicants: Prof. C.G. Figdor (RadboudUMC), Prof. P. Gros (Utrecht University), Prof. A.J.R. Heck (Utrecht University), Prof. H.S. Overkleeft (Leiden University), Prof. T.N.M. Schumacher (Netherlands Cancer Institute)
Host institution: LUMC
Amount awarded: EUR 27.600.000
Our immune system protects us against infectious diseases and cancer. Its failure to function properly can result in unpleasant consequences. However, if the immune system unintentionally works too well then autoimmune diseases can develop where the immune system attacks the body, as is the case with rheumatoid arthritis and multiple sclerosis. In the Institute for Chemical Immunology (ICI) the top in Immunology and Chemistry will join forces to develop a new discipline: Chemical Immunology. The aim is to use chemistry to understand immune diseases and to find solutions for situations where the immune system fails or is too active. This combination of disciplines can bring about a radical change in the approach to autoimmune diseases, infections and cancer.