LUMC Light and Electron Microscopy Facility

Science and collaborations

The services provided by the Light and Electron Microscopy Facility are indispensable for almost every research department within the LUMC. For example, we have close collaborations with Anatomy, Chemical Immunology, Embryology, Endocrinology, Gynecology, Human Genetics, Immunology, Infectious Disease, Kidney Disease, Nephrology, Neurology, Neurophysiology, Ophthalmology, Parasitology, Pathology, Pulmonology, Radiology, Rheumatology, Vascular surgery, Virus and Stem Cell Biology (alphabetical order).

We further collaborate with the Leiden University Institute of Chemistry (LIC), Institute of Biology of Leiden University (IBL), Leiden University Academic Centre for Drug Research (LACDR), University of Amsterdam, Naturalis, Helsinki University, Erasmus Medical Centre, TU Delft, NKI, TNO Leiden, University of Twente.

In order to maintain and expand the state-of-the-art imaging techniques, we implement and develop new imaging techniques. Current research interests involve super-resolution, cryo light microscopy, correlative microscopy and volume imaging.

Our main research projects fall within the medical research profile areas 'Immunity, Infection and Tolerance' and 'Biomedical Imaging' of the LUMC. Two main lines of research within 'Immunity, Infection and Tolerance' are 'Virus Replication' and 'DNA nano patterning'. Within the research profile 'Biomedical Imaging' we use state-of-the-art electron microscopy, image processing and visualization techniques. We also develop correlative light and electron microscopy techniques and workflows for applications in medicine, biology and chemistry.