Paroxysmal Cerebral Disorders (PaCD)
In the PaCD research programme we study the clinical features, diagnosis, epidemiology, socio-economic impact, structural and functional cerebral consequences, pathophysiology, and treatment of highly disabling and mechanistically related brain disorders that are primarily characterised by recurring attacks of disabling (sub)acute transient cerebral dysfunction.
Aim and focus
The research programme is focused at the most relevant and prevalent paroxysmal cerebral disorders: migraine, cluster headache, narcolepsy, syncope and epilepsy to unravel the spectrum of neurobiological causes and consequences of these episodic brain disorders. The aim is to predict and prevent attacks, to unravel targets for drug treatment, to develop tailored (including sex-specific) treatments and to test novel treatment modalities.