Research Group Real World Data

Real World Data provide information on the efficiency and safety of new drugs and how drugs are used after being released to the market. We study Real World Data to learn which patients are treated with new drugs, what dose is being used, what and how many (rare) adverse events occur and how efficient they are. Data on plasma concentrations, safety and efficacy, all in relation to patient parameters and experiences, contribute to optimize the use of new released drugs in individual patients.

New techniques, such as artificial intelligence, data mining and natural language processing, are used to efficiently search the EPD for Real World Data. Real World Data are collected in registries and for quality purposes too and end up in databases making larger datasets available. This enables us to personalize therapy based on patient characteristics in unselected populations. Applications or other digital technologies are applied to collect patient experiences.

…

New techniques, such as artificial intelligence, data mining and natural language processing, are used to efficiently search the EPD for Real World Data. Real World Data are collected in registries and for quality purposes too and end up in databases making larger datasets available. This enables us to personalize therapy based on patient characteristics in unselected populations. Applications or other digital technologies are applied to collect patient experiences.

In our group we closely collaborate with the LUMC department of Epidemiology, the Dutch pharmacovigilance center Lareb and Haga hospital The Hague.

We focus our research questions on the following themes:

  • New treatments in oncology
  • Efficacy and safety in personalized medicine
  • Pharmacovigilance

Projects

Themes for Innovation

Key Publications

Our team

  • Dr. Juliette Zwaveling - hospital pharmacist, clinical pharmacologist
  • Dr. Kim Gombert-Handoko - hospital pharmacist, clinical epidemiologist
  • Dr. Agnes Kant - epidemiologist
  • Dr. Nienke van Rein - hospital pharmacist, clinical epidemiologist, clinical pharmacologist
  • Hanieh Abedian Kalkoran - PhD student