Student research projects

student

Within the Leiden Malaria Group, there are possibilities for students to do a research traineeship (study: Medicine, Biological Sciences, (Medical) Biology, HBO/Polytechnic). Actual information about traineeship possibilities within the research projects can be found on the Leiden University Blackboard

See also the 'Guide to internships' on the website of the Research Profile 'Immunity, Infection and Tolerance' .

For more information, please contact Dr. Blandine M.D. Franke-FayardDr. Shahid M. Khan or Dr. Chris J. Janse

Former and current student research projects (2007 - 2015)

Pika Gomboc, VU Amsterdam, Biomedische Wetenschappen, master
Period: February  2016 - August 2016
Place: LUMC
Title: Characterization of liver stage Plasmodium genes as potential GAP vaccine candidates & investigation of optimal route of administration

Jelte Krol, Leiden University, BFW, master
Period: October 2015 - July 2016
Place: LUMC
Title: The use of genetically attenuated parasites to examine the effect of skin residing sporozoites on malaria vaccine efficacy

Mayuri Nalawade, Master National University of Ireland
Period: April 2015 - September 2015
Place: LUMC
Title: Generation and analysis of transgenic P. yoelii malaria parasites to study skin immunology

Brian Kruisinga
, HLO/Polytechnic Rotterdam
Period: November 2014 - June 2015
Place: LUMC
Title: Development of  a second generation malaria vaccine based on genetically attenuated parasites.
Lisa Welt, HLO/Polytechnic Leiden
Period: September 2014 - June 2015
Place: LUMC
Title: Generation of transgenic P. yoelii malaria parasites to optimize the effectiveness of the vaccination protocol

Rick Hennevelt, HLO/Polytechnic Leiden
Period: September 2014 - June 2015
Place: LUMC
Title: Improving P. falciparum transfection and creating the next generation genetically attenuated P. falciparum parasites for vaccination

Hester Koppejan, Leiden University, BW, master
Period:  April 2014 - November 2014
Place: LUMC
Title: Role of skin immunology in the study of protective immunity in different regimes of malaria vaccine administration regimes

Niels de Wilde, VU, BW, master
Period:  February 2014 - August 2014
Place: LUMC
Title: Improving gene deletion/insertion tranfection methodologies in Plasmodium falciparum

Marta Reguera Gómez, Universidad de Alcalá (Spanje), bachelor
Period:  January 2014 - June 2014
Place: LUMC
Title: Generation and analysis of transgenic malaria parasite lines to indentify antigens as suitable targets for a vaccine

Tim Christen
, Leiden University, BW, master
Period:  April 2013 - November 2013
Place: LUMC
Title: Developing a method to induce knock-out, double knock-out and gene insertion transfections in P. falciparum

Yvette Gladdines, HLO/Avans Hogeschool Breda
Period:  December 2012 - June 2013
Place: LUMC
Title: Protein export in hepatocytes in the liver stage of malaria parasites

Fiona van Pul, HLO/Polytechnic Leiden
Period:  September 2012 - May 2013
Place: LUMC
Title: Making successful transfection in human malaria parasites and examination in primary human liver cells using several constructs for the development of a liver-stage vaccine

Tracy-Jane Eisden, VU, BW, master
Period: February 2012 - August 2012
Place: LUMC
Title: Generation of transgenic malaria parasites to serve as a foreign antigen expression system for immunisation

Paula Schreurs, VU, BW, master
Period: February 2012 - August 2012
Place: LUMC
Title: Optimization of the expression PfEMP1 domains on the outer surface membrane of malaria infected erythrocytes

Janneke Eken, HLO/Polytechnic Leiden
Period:  January - September 2012
Place: LUMC
Title: Targeting malaria proteins exported on the surface membrane of infected erythrocytes

Pascale Bouchier, VU, BW, master
Period: February 2011 - July 2011
Place: LUMC
Title: The generation and characterization of genetically modified ‘vehicle’ malaria parasites

Hedayat Amini, VU, BW, master
Period: February 2011 - July 2011
Place: LUMC
Title: The next generation of genetically modified malaria parasites that may serve as potential live-vaccine

Adik Adamian, VU, BW, master
Period:  February 2010 - August 2010
Place: LUMC
Title:  Towards falciparumized P. berghei binding human ICAM-1

Jasper Misset, Leiden University, Biology, bachelor
Period:  January 2010 – August 2010
Place: LUMC
Title:  Using malaria parasites as vehicles to deliver heterelogous antigens

Joana Pissarra, University of Lisbon (Portugal), master
Period:  December 2009 – July 2010
Place: LUMC
Title:  Development of new tools to target the liver stage of malaria parasites

Avinash Dinmohamed, VU, BW, master (Master’s Literature Review)
Period:  February 2010 - April 2010
Place: LUMC
Title:  The 6-cys gene family: The ‘Vaccine Family’ of Plasmodium Proteins

Stefan Lelieveld, HLO/Polytechnic Leiden
Period:  November 2009 – May 2010
Place: LUMC
Title:  Bioinformatic characterization of the Pb-fam multigene family in the rodent malaria parasite Plasmodium berghei

Ralf Boland, Leiden University, Biology, bachelor
Period:  September 2009 – April 2010
Place: LUMC
Title:  Expression of PfEMP1 domains on the surface of malaria infected red blood cells

Mariela Fuentes Caraballo, University of Puerto Rico (USA), master
Period:  May 2009 – July 2009
Place: LUMC
Title:  Characterization and understanding of the biological role of the Multidrug Resistance Associated Protein of malaria parasites

Maria Gonzalez Pons, University of Puerto Rico (USA), PhD student
Period:  May 2009 – July 2009
Place: LUMC
Title:  Characterization and understanding of the biological role of the Multidrug Resistance Associated Protein of malaria parasites

Reindert Emmens, VU, BW, master
Period:  February 2009 – August 2009
Place: LUMC
Title:  Targeting of malaria parasite proteins to the surface of infected red blood cells

Avinash Dinmohamed, VU, BW, master
Period:  February 2009 – August 2009
Place: LUMC
Title:  Identification of factors important for protein trafficking in the malaria parasite

Carlijn van der Sluijs, VU, BW, bachelor
Period:  November 2008 – April 2009
Place: LUMC
Title:  Targeting of malaria parasite proteins to the surface of infected red blood cells

Jolle Mijs Vegter, VU, BW, master
Period:  October 2008 – May 2009
Place: LUMC
Title:  Inducible knockout of genes in malaria parasites: targeting essential genes

Marc-Manuel Hahn, VU, BW, master
Period:  February 2008 – September 2008
Place: LUMC
Title:  Role of the malaria parasite protein HEP17 in development in the liver

Maarten Eldering, VU, BW, master
Period:  February 2008 – September 2008
Place: LUMC
Title:  Characterization of an inducible transfection system in malaria parasites

Onny Klop, HLO/Polytechnic Breda
Period:  February 2008 – October 2008
Place: LUMC
Title:  The generation of new red transgenic reporter lines of a rodent malaria parasite for in vivo visualization of host-pathogens interactions

David Janson, Leiden University, BW, master
Period:  September 2007 – June 2008
Place: LUMC
Title:  In vivo visualization of rodent malaria parasites: generation and exploitation of a humanized model

Aycha Bleeker, HLO/Polytechnic Leeuwarden
Period:  September 2007 –March 2008
Place: LUMC
Title:  The generation of transgenic malaria parasites expressing reporter proteins for drug test screening and in vivo visualization