Neuroimaging in cerebral small vessel disease/dementia and neuro-oncology
The main research lines embedded within this research group are the following:
- Development of new cerebrovascular MRI markers that are able to contribute to early identification of patients at risk for cognitive decline and dementia.
- Development of new brain MRI markers in neuropsychiatric lupus erythematosus for treatment monitoring aimed at prevention of cognitive decline.
- Development of new 7T (ultra-high field) brain MRI markers in patients with a brain glioma aimed at prediction of tumor genotype and at prediction of tumor progression after treatment.
The main research lines embedded within this research group are the following:
- Development of new cerebrovascular MRI markers that are able to contribute to early identification of patients at risk for cognitive decline and dementia.
- Development of new brain MRI markers in neuropsychiatric lupus erythematosus for treatment monitoring aimed at prevention of cognitive decline.
- Development of new 7T (ultra-high field) brain MRI markers in patients with a brain glioma aimed at prediction of tumor genotype and at prediction of tumor progression after treatment.
Over the years multiple novel MRI markers of cerebral small vessel disease have been developed within this research group, such as white matter hyperintensity shape, assessment of small deep grey matter infarcts and cortical micro-infarcts at ultra-high field (7T) MRI and machine learning models to analyze MRI markers in a combined way. Other research topics include the clinical value of MRI markers of brain clearance (the glymphatic system).
Themes for Innovation
Key publications
Team members
Dr. Jeroen de Bresser, neuroradiologist/PI (J.H.J.M.de_Bresser@lumc.nl)
Research line 1: Brain MRI markers in cerebral small vessel disease/dementia
PhD students: Dr. Rashid Ghaznawi, Drs. Jasmin Keller, Drs. Martijn Nagtegaal, Drs. Faisal Hassan.
Associated faculty: Prof.dr.ir. Thijs van Osch (professor Gorter Center), Dr. Frans Vos (associate professor TU Delft), Prof.dr. Simon Mooijaart (internist-geriatrician).
…Team members
Dr. Jeroen de Bresser, neuroradiologist/PI (J.H.J.M.de_Bresser@lumc.nl)
Research line 1: Brain MRI markers in cerebral small vessel disease/dementia
PhD students: Dr. Rashid Ghaznawi, Drs. Jasmin Keller, Drs. Martijn Nagtegaal, Drs. Faisal Hassan.
Associated faculty: Prof.dr.ir. Thijs van Osch (professor Gorter Center), Dr. Frans Vos (associate professor TU Delft), Prof.dr. Simon Mooijaart (internist-geriatrician).
Research line 2: Brain MRI markers in neuropsychiatric lupus erythematosus
PhD student: Drs. Francesca Inglese.
Associated faculty: Dr. Margreet Steup-Beekman (Rheumatologist), Prof.dr. Tom Huizinga (Rheumatologist), Dr. Itamar Ronen (researcher).
Research line 3: Brain MRI markers in neuro-oncology
PhD students: Drs. Bárbara Schmitz Abecassis, Drs. Daniëlle van Dorth.
Associated faculty: Prof.dr.ir Thijs van Osch (professor Gorter Center), Dr. Johan Koekkoek (neurologist), Prof.dr. Martin Taphoorn (neurologist), Dr. Linda Dirven (researcher).