C.J.Gorter MRI Center

Pre-clinical imaging

In our research group we develop and apply MRI techniques to study physiology and pathology in animal models of disease, and in post-mortem human tissue.

In vivo imaging allows us to study biological systems and animals non-invasively. Our group uses a range of state-of-the-art imaging systems, including MRI, CT, SPECT and optical systems to develop techniques to visualise the anatomy, function of specific organs or image specific cellular and molecular targets.

We specialize in imaging markers of neurodegenerative and neurovascular disorders, using MRI in combination with other imaging techniques and histology and molecular biology to link imaging phenotypes to biological substrates. This is possible due to the strong links with the department of Human Genetics, where Dr. Van der Weerd is also appointed.

In vivo imaging allows us to study biological systems and animals non-invasively. Our group uses a range of state-of-the-art imaging systems, including MRI, CT, SPECT and optical systems to develop techniques to visualise the anatomy, function of specific organs or image specific cellular and molecular targets.

We specialize in imaging markers of neurodegenerative and neurovascular disorders, using MRI in combination with other imaging techniques and histology and molecular biology to link imaging phenotypes to biological substrates. This is possible due to the strong links with the department of Human Genetics, where Dr. Van der Weerd is also appointed.

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Non-invasive in vivo imaging plays an important role in our strategies to reduce and refine animal research. Longitudinal imaging allows us to monitor time courses or treatment response within the same animal, thus improving the reliability of the experiment and reducing the number of animals needed.

In our group, we also work on the development of imaging techniques or analysis methods that will help to reduce to number of animals needed.

Non-invasive in vivo imaging plays an important role in our strategies to reduce and refine animal research. Longitudinal imaging allows us to monitor time courses or treatment response within the same animal, thus improving the reliability of the experiment and reducing the number of animals needed.

In our group, we also work on the development of imaging techniques or analysis methods that will help to reduce to number of animals needed.

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Team members

  • Louise van der Weerd, Associate professor
  • Ernst Suidgeest, Technician
  • Whitney Freeze, Post-doctoral researcher
  • Boyd Kenkhuis, PhD student
  • Sabine Voigt, PhD student
  • Tom Metz, PhD student
  • Sanny Scheffer, PhD student
  • Marjolein Bulk, Post-doctoral researcher (guest)