Key publications

Publications:

1. Collins J., Robinson C., Danhof H., Knetsch C. W., van Leeuwen H. C., Lawley T. D., Auchtung J. M., Britton R. A.. Dietary trehalose enhances virulence of epidemic Clostridium difficile. Nature 2018-Jan-18;553(7688). (Web of Science)
2. van Eijk Erika, Paschalis Vasileios, Green Matthew, Friggen Annemieke H., Larson Marilynn A., Spriggs Keith, Briggs Geoffrey S., Soultanas Panos, Smits Wiep Klaas. Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile. Open biology 2016-Dec-31;6(12). (Web of Science)
3. Smits WK, Lyras D, Lacy DB, Wilcox MH, Kuijper EJ. Clostridium difficile infection. Nature reviews disease primers 2016-Apr-07;2. (Web of Science)
4. van Eijk Erika, Anvar Seyed Yahya, Browne Hilary P., Leung Wai Yi, Frank Jeroen, Schmitz Arnoud M., Roberts Adam P., Smits Wiep Klaas. Complete genome sequence of the Clostridium difficile laboratory strain 630 Delta erm reveals differences from strain 630, including translocation of the mobile element CTn5. Bmc genomics 2015-Jan-31;16. (Web of Science)
5. Knetsch C. W., Connor T. R., Mutreja A., van Dorp S. M., Sanders I. M., Browne H. P., Harris D., Lipman L., Keessen E. C., Corver J., Kuijper E. J., Lawley T. D.. Whole genome sequencing reveals potential spread of Clostridium difficile between humans and farm animals in the Netherlands, 2002 to 2011. Eurosurveillance 2014-Nov-13;19(45). (Web of Science)
6. Hensbergen Paul J., Klychnikov Oleg I., Bakker Dennis, van Winden Vincent J. C., Ras Nienke, Kemp Arjan C., Cordfunke Robert A., Dragan Irina, Deelder Andre M., Kuijper Ed J., Corver Jeroen, Drijfhout Jan W., van Leeuwen Hans C.. A Novel Secreted Metalloprotease ( CD2830) from Clostridium difficile Cleaves Specific Proline Sequences in LPXTG Cell Surface Proteins. Molecular & cellular proteomics 2014-May-31;13(5). (Web of Science)
7. van Nood Els, Vrieze Anne, Nieuwdorp Max, Fuentes Susana, Zoetendal Erwin G., de Vos Willem M., Visser Caroline E., Kuijper Ed J., Bartelsman Joep F. W. M., Tijssen Jan G. P., Speelman Peter, Dijkgraaf Marcel G. W., Keller Josbert J.. Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile. New england journal of medicine 2013-Jan-31;368(5). (Web of Science)
8. He Miao, Miyajima Fabio, Roberts Paul, Ellison Louise, Pickard Derek J., Martin Melissa J., Connor Thomas R., Harris Simon R., Fairley Derek, Bamford Kathleen B., D'Arc Stephanie, Brazier Jon, Brown Derek, Coia John E., Douce Gill, Gerding Dale, Kim Hee Jung, Koh Tse Hsien, Kato Haru, Senoh Mitsutoshi, Louie Tom, Michell Stephen, Butt Emma, Peacock Sharon J., Brown Nick M., Riley Tom, Songer Glen, Wilcox Mark, Pirmohamed Munir, Kuijper Ed, Hawkey Peter, Wren Brendan W., Dougan Gordon, Parkhill Julian, Lawley Trevor D.. Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nature genetics 2013-Jan-31;45(1). (Web of Science)
9. Bauer MP, Notermans DW, van Benthem BHB, Brazier JS, Wilcox MH, Rupnik M, Monnet DL, van Dissel JT, Kuijper EJ. Clostridium difficile infection in Europe: a hospital-based survey. Lancet 2011-Jan-01;377(9759):63-73. (Web of Science)
10. Goorhuis A, Bakker D, Corver J, Debast SB, Harmanus C, Notermans DW, Bergwerff AA, Dekker FW, Kuijper EJ. Emergence of Clostridium difficile infection due to a new hypervirulent strain, polymerase chain reaction ribotype 078. Clinical infectious diseases 2008-Nov-01;47(9):1162-1170. (Web of Science)