Innovation in Health Strategy and Quality of Care

Our Research

The focus of health care is rapidly changing. The need for maximum gains with minimal input requires tailored health care strategies and an ever more explicit evaluation of health benefits for the patient, leading to a different role of the University Medical Centres.

cochleair implantaat

The medical research profile Innovation in Health Strategy and Quality of Care (IHQC) aims at providing a scientific basis for these changes. It stimulates the development of innovations that contribute to higher efficiency, better quality of care and increased patient-centeredness, without increasing costs. Examples of innovations include the application of various organizing principles, E-Health and more efficient application available data.

Increasingly, we should demonstrate not just what we do in health care, but what this contributes for the patient in terms of process and health outcomes. This will lead to a stronger focus on appropriate care (“gepast gebruik”). The mission of the medical research profile IHQC is to increase knowledge on cost-effective ways to improve patient experiences and outcomes in health care, by excellent research at the crossroads of clinical medicine and fundamental science, and of public health, primary - and secondary care. The research program aims both to evaluate healthcare innovations that improve quality of care, and to develop novel methods for the evaluation of health innovations and quality of care.

Focus on two major research topics

Our research theme’s, as described under Programmes, culminate in two overarching topics aimed at improving health care quality:

  • Personalized Health care: innovative strategies for prevention and patient-centeredness in healthcare
  • SMART- surgery: Scientific Meaningful Assessment of Reconstructive & Tailored Surgery  

SMART-Surgery: Scientific Meaningful Assessment of Reconstructive & Tailored Surgery

The development and assessment of complex minimal invasive, image-guided or reconstructive surgery in gynaecology, Ear Nose and Throat surgery and other surgical subspecialties calls for evidence-based outcome assessment.  This research topic has a focus on the surgical top referral care (TRFs) of the LUMC. All domains are linked to rigorous methodological research (epidemiological, health services research or medical decision making, and health technology assessment) and to the other LUMC medical research profiles where appropriate. The theme has strong links with the Leiden BaMa program.

Contact information: Prof. dr. F.W. Jansen ( and Prof. dr. W.C. Peul (

Personalized Health care: innovative strategies for prevention and patient-centeredness in healthcare

This research topic focuses on structured intervention programs and tailored health care strategies to be used in individual patients and populations at risk inside and outside of the hospital. Prediction models and decision support algorithms based on routine healthcare data, clinical and genetic datasets (precision medicine) are increasingly used to prioritize and tailor medicine in many fields, ranging from acute to chronic care and from primary care to specialized oncology.

Such a tailored approach also includes patient values in a patient-centered style of shared decision-making and self-management, in order to find care gaps, to increase efficacy and efficiency of treatment, to reduce overtreatment  and to improve adherence. Screening of routine care data reveals care gaps and enables risk adjustment to improve planning of care (panel management). Outcome monitoring of treatment in routine care facilitates continuous tailoring of treatment and follow-up towards optimal results. LUMC groups cooperating in this area combine expertise on:

  • development and validation of prediction models, diagnostic classifications, and  the analysis and interpretation of personal genome sequences;
  • tailoring of prevention, diagnosis and treatment towards patient goals and values (value-based health care); 
  • the application of routine care data and routine outcome measures (ROM) for risk assessment and care-gap monitoring (population care and panel management);
  • eHealth applications;
  • population health management.
Contact information: Prof. dr. M.E. Numans ( and Prof. dr. J.G. van der Bom ( 

Dutch science agenda

The medical research profile Innovation in Health Strategy and Quality of Care participates in the Nationale Wetenschapsagenda (in dutch).