Onderzoek en Innovatie

Aim and focus
In society, impairments and limitations of mobility have a major and increasing impact on the independency and quality of life of many persons and pose a large economic burden to society as well. As for more common conditions, in The Netherlands about 60,000 patients have a knee or hip arthroplasty, 55,000 persons suffer from hip, ankle or wrist fractures, and more than 25,000 from stroke annually, all with varying clinical outcome after intervention. The latter resulted in the overarching research theme of "Mobility", encompassing Musculoskeletal (MSK) pathology and Brain and nerve injuries. Unsatisfactory outcomes and complications are common in all designated subgroups of patients, leading to significant health care usage and loss of productivity. In order to address this issues, the research program focusses on two research themes: "Prognostic Clinical Modelling" and "Optimising Clinical Outcome". The related conditions are common pathology (with huge societal impact), therefor this research is performed within regional clinical networks. Next to these more common clinical conditions, specific top-referral (TRF) clinical cases (i.e. specialised low volume cases with multidisciplinary diagnostics and treatment options), like bone and soft tissue tumours, pelvic fractures, neuromuscular conditions, are treated and evaluated within research subprogrammes of the departments of Orthopaedics, Trauma Surgery and Rehabilitation Medicine.
The research program is built on the extensive experience of clinical network building as well as methodological expertise on the development, evaluation and implementation of complex care and technology.  By aiming at the better selection of patients for specific management strategies (prognostic clinical modelling) and optimising care delivery by improving transparency, monitoring and vigilance of effectiveness and safety by means of national and regional registries and clinical networks (Optimising clinical outcome) the program significantly contributes to the concept of Value Based Health Care. 
The two common research themes with their subsequent subprograms are:

1. Prognostic Clinical Modelling 

2. Optimising Clinical Outcome