Publications

1. Zelensky AN, Schimmel J, Kool H, Kanaar R, Tijsterman M. (2017) Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA. Nature Communications. doi: 10.1038/s41467-017-00124-3. 

2. Van Kregten M, de Pater S, Romeijn R, Van Schendel R, Hooykaas P, Tijsterman M. (2106) T-DNA integration in plants results from polymerase Theta-mediated DNA repair. Nature Plants. doi:10-1038/nplants.2016.164. 

3. Lemmens B, van Schendel R, Tijsterman M. (2015) Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers. Nature Communications. doi:10.1038/ncomms9909. 

4. Van Schendel R, Roerink SF, Portegijs V, van den Heuvel S, Tijsterman M. (2015) Polymerase theta is a key driver of genome evolution and of CRIPR/Cas9-mediated mutagenesis. Nature communications. doi : 10.1038/ncomms8394. 

5. Koole W, van Schendel R, Karambelas A, van Heteren JT, Okihara KL, Tijsterman M. (2014) A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites. Nature communication, 5, 3216

All publications