Publications

1. Vukic M, Daxinger L. DNA methylation in disease: Immunodeficiency, Centromeric instability, Facial anomalies syndrome. Essays Biochem. 2019 Nov 14. pii: EBC20190035. doi: 10.1042/EBC20190035.

2. Wu H, Vonk KKD, van der Maarel SM, Santen GWE, Daxinger L. A functional assay to classify ZBTB24 missense variants of unknown significance. Hum Mutat. 2019 Aug;40(8):1077-1083. doi: 10.1002/humu.23786.

3. Vukic M, Wu H, Daxinger L. Making headway towards understanding how epigenetic mechanisms contribute to early-life effects. Philos Trans R Soc Lond B Biol Sci. 2019 Apr 15;374(1770):20180126. doi: 10.1098/rstb.2018.0126.

4. Li S, Yen L, Pastor WA, Johnston JB, Shew C, Du J, Liu W, Ho J, Stender B, Clark AT, Burlingame A, *Daxinger L, *Patel DJ, *Jacobsen SE. Mouse MORC3 is an ATP dependent dimer involved in gene silencing that localizes to H3K4me3-marked chromatin. PNAS 2016; doi:10.1073/pnas.1609709113. (*shared senior author). 

5. Wu H, Thijssen EP, de Klerk E, Vonk KKD, Wang J, den Hamer B, Aytekin C, van der Maarel SM, Daxinger L. Converging disease genes in ICF syndrome: ZBTB24 controls expression of CDCA7 in mammals. Hum. Mol. Genet. 2016 doi: 10.1093/hmg/ddw243. 

6. Isbel L, Prokopuk L, Wu H, Daxinger L, Oey H, Spurling A, Lawther A, Hale M, Whitelaw E. Widely interspaced zinc finger motifs, Wiz, binds promoters containing CTCF-binding sites and is required for normal neural function in the mouse. Elife. 2016 Jul 13;5. pii: e15082. doi: 10.7554/eLife.15082.

7. Daxinger L, Harten SK, Oey H, Epp T, Isbel L, Huang E, Whitelaw N, Apedaile A, Sorolla A, Yong J, Bharti V, Sutton J, Ashe A, Pang Z, Wallace N, Gerhardt D, Blewitt ME, Jeddeloh JA, Whitelaw E. An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse. Genome Biology. 2013,14:R96 (*shared first author).

8. Daxinger L and Whitelaw E. Understanding transgenerational epigenetic inheritance via the gametes in mammals. Nat Rev Genet. 2012, 13:153-62