Participating Bioinformaticians
The following bioinformatics experts can be consulted in their listed areas of expertise. Contact them either directly or through one of the members of the Core.
Participating departments
- Human Genetics
- Medical Microbiology
- Medical Statistics and Bioinformatics
- Molecular Cell Biology
- Parasitology
- Pathology
Department of Pathology
Dr. Jan Oosting
- array analyse
- - SNP (genotypering, numerieke afwijkingen)
- - Expressie
- Pathway analyse
Ronald van Eijk PhD (Klinisch Moleculair Bioloog in de Pathologie (i.o.))
- Molecular Technology
- Molecular pathology
- Next Generation Sequencing
- Liquid Biopsy
- DNA/RNA variant analysis
- www.linkedin.com/in/ronaldvaneijk/
Center for Proteomics en Metabolics
Dr. Magnus Palmblad
- Proteomics experiment design
- Mass spectrometry data analysis
Department of Molecular Cell Biology
Dr. Ir. Hans Vrolijk
- microscopic image acquisition
- image processing and data analysis
Ing. Willem Sloos
- microscopic image acquisition
- image processing and data analysis
Dr. Raimond Ravelli (Molecular Cell Biology, section Electron Microscopy)
- X-ray structure determination
- Macromolecular structure analysis
- Electron microscopy
- Image processing
- Automated data collection and analysis
Prof. dr. Bram Koster
- Electron microscopy
- 3D electron microscopy
- Cryo electron microscopy
Dr. Frank Faas
- Electron microscopy
- Image processing
- Automated data collection, aquisition and analysis
- Software development
Department of Medical Statistics and Bioinformatics
Dr. Erik van Zwet (assistant professor, medical statistics)
- statistics
- data analysis
Dr. Bart Mertens (Statistical methods for high-dimensional bioinformatics)
- Proteomics and metabon(l)omics
- Mass spectrometry, NMR and NIR spectra
- Spectral modeling
- Peak identification
- Spectral pre-processing
- Diagnostic and prognostic models
Prof. dr. Joost N. Kok
- Algoritmen
- Data Management
- Data Mining
- Software Technologie
Dr. Stefan Böhringer
- Statistical genetics
- Genome wide association analysis
- High-dimensional traits
- Heritability analysis
- Haplotype analysis
- Population Genetics
- Population stratification
- Programming languages and computational problems
- Databases and analysis pipelines
Department of Medical Microbiology
Prof.Dr. Sasha Gorbalenya (LUF Professor of Applied Bioinformatics in Virology)
- Comparative sequence analysis
- Virus phylogeny
- Structure-function analysis
Department of Human Genetics
Dr. Jan Bert van Klinken (Scientific Researcher Human Genetics)
- systems biology (mathematical modelling, simulation, stoichiometric analysis)
- pathway analysis
- multivariate statistics
- indirect calorimetry
Dr. Peter Taschner
- Human Genome Variation nomenclature
- Locus-specific mutation databases
- Primer design
- Data mining using the internet
Dr. Marco Roos
- e-Science (workflow, semantic web, e-laboratories)
- Hypothese ondersteuning gebaseerd op text-mining
- Bioinformatica
- Moleculaire Cytologie
Dr. Jeroen F. J. Laros (Head of bioinformatics at the LGTC.)
- High throughput sequencing
- Human Genome Variation nomenclature
- Algorithms / Programming
- Computer networks / Operating systems
- Locus specific databases
Dr. Peter-Bram 't Hoen (Universitair Docent, hoofd Human Genetics Bioinformatics Research Group )
- bioinformatics
- next generation sequencing
- genome-based medicine
- expression profiling
- RNA-seq
- personal
- gebruik van biomedische literatuur voor analyse en interpretatie van high-throughput datasets
- biomarkers
Bioinformatics Core
Drs. Ramin Monajemi (Senior researcher)
- Bio-informatica
Dr. Szymon M. Kielbasa (Assistant Professor, Bioinformatics Center for Expertise )
- sequence alignment
- large scale analysis of high-throughput sequencing data
- comparative sequence analysis
- prediction of transcriptional regulation
- modelling of transcription factor binding
- algorithms/pipeline development
- programming (D, C/C++, R, PERL)