A.M. Stiggelbout

hoogleraar medisch besliskunde




  • Co-chair LUMC research profile area ‘Health Innovation and Quality of Care”
  • Deputy-chair of the Department of Medical Decision Making, LUMC
  • Member NFU-Faculty Executive Master Quality and Safety of Patient Care
  • Member “Commissie Bevolkingsonderzoek” (Population Screening) Gezondheidsraad 2013
  • Member of the Program Committee of the Leiden International Medical Student Conference 2015
  • Chair of the Working Party “Teaching and Training”, of the National Platform  Shared Decision Making 2012-
  • Vice-chair of the subcommittee Research on Effectiveness and Efficiency, Program “Prevention”, The Netherlands Organisation for Health Research and Development - Medical Sciences (ZonMw)

Program “Prevention”, The Netherlands Organisation for Health Research and Development - Medical Sciences (ZonMw)

Recent publication in BMJ on Shared Decision Making here.

Salzburg Statement on Shared Decision Making in English and Nederlands

Curriculum Vitae and list of publications

2008 oratie Leiden


Prof. Stiggelbout’s research focuses on two major themes. The first concerns individual patient decision making, broadly speaking the role of the patient and of his/her preferences in medical decision making. This research involves doctor-patient communication, with emphasis on risk communication, as a constituent of shared decision making. The research is both methods-focuses and implementation-focused. Further, normative and ethical aspects of medical decision making are topic of this line of research. The second theme concerns the incorporation of quality of life and preferences in meso- and macro-level decision making. This theme concerns mostly research on methods to assess quality of life and health state preferences/utilities, e.g. in cost-effectiveness analysis and health technology assessment. All of the above, as well as clinimetrics are a major part of Prof. Stiggelbout’s consultations for clinical departments of the LUMC.


Dr. Stiggelbout's teaches various courses in the Medical Curriculum of the Leiden University, as well as courses in Continuing Medical Education nationally. Topics involve e.g. quality of life research, preference assessment, shared decision-making and risk communication.

Recent Grants

  • Pieterse AH, Stiggelbout AM, Van der Weijden T. Developing and validating measures for Shared Decision Making in Oncology (Dutch Cancer Society UL 2013-6108) –€ 477.000
  • Liefers GJ, Stiggelbout AM, Van de Velde CJH. Elderly patients’ preferences for early stage breast cancer treatment. (Pink Ribbon; WO2012-6 (2012-2014)) - € 149.500
  • Liefers GJ, Stiggelbout AM, Van de Velde CJH. ‘Climb every mountain’ - physical exercise in elderly breast cancer survivors. (Alpes d’Huzes/Dutch Cancer Society; UL 2011-5263 (2012-2014) - € 470.000
  • Stiggelbout AM, Van den Hout WB. Development and validation of a functioning scale for Cervical Radicular Syndrome (ZonMW 80-82310-97-12200 (2012-2014)) - € 72.000
  • Communicating risk from prediction models in the clinical encounter (Stiggelbout, De Haes, Nortier. Dutch Cancer Society UL-2010-4805 (2011-2015))
  • Web-based time trade-off incorporating interviewer help: efficiency with validity. (Peeters, Stiggelbout, Van den Hout. ZonMw 80-82500-98-10211 (2011-2013))
  • Sexual complaints in female cancer survivors: Is there a need for treatment? (Ter Kuile, Stiggelbout, Kenter. Alpes d’Huzes/Dutch Cancer Society; UL 2010-4716 (2011-2015))
  • Tailored patient values elicitation task for rectal cancer treatment decision-making (Pieterse, Stiggelbout, Marijnen. Dutch Cancer Society UL-2009-4431; 2010-2014)
  • Fertiliteitssparende technieken bij jonge vrouwen: een subjectieve evaluatie van de  procedurele en psychosociale aspecten (Ter Kuile, Stiggelbout, Hilders. DSW Healthcare; 2009-2013)
  • Health checks in vulnerable groups: the role of beliefs and expectations. (Stiggelbout AM, Assendelft WJJ, Maes S. Collaborating Dutch
    Health Funds – Program “Lekker Lang Leven” 2009-2012)
  • VIDI-Award
    from the Innovational Research Incentives Scheme of the Netherlands Organisation for Scientific Research (NWO); grant entitled
    "Health state valuations: bridging the gap between the imagined and the real"
    (Stiggelbout AM, NWO, 2005-2009).
  • Incorporating Temporary Health States into Decision Support: Women’s Interactive System for Decisions on Menopause – a Practical Approach to Temporary Health States (WISDOM + PATHS) (Col NF. Agency for Health Care Research and Quality 2 R01 HS013329-04A1 2005-2008) Consultant.



  • Alden D, Friend J, Shapira M, Stiggelbout AM. Cultural Targeting and Tailoring of Shared Decision Making Technology:  A Theoretical Framework for Improving the Effectiveness of Patient Decision Aids in Culturally Diverse Groups. Soc Sci Med. 2014;105C:1-8
  • Edelaar-Peeters Y, Stiggelbout AM, Van Den Hout WB. Qualitative and Quantitative Analysis of Interviewer Help Answering the Time Tradeoff. Med Decis  Making. 2014 Mar 25. [Epub ahead of print]
  • Engelhardt EG, Garvelink MM, de Haes JH, van der Hoeven JJ, Smets EM, Pieterse AH, Stiggelbout AM. Predicting and communicating the risk of recurrence and death in women with early-stage breast cancer: a systematic review of risk prediction models. J Clin Oncol. 2014;32:238-50 
  • Snijders HS, Kunneman M, Bonsing BA, de Vries AC, Tollenaar RA, Pieterse AH, Stiggelbout AM. Preoperative risk information and patient involvement in surgical treatment for rectal and sigmoid cancer. Colorectal Dis. 2014;16:O43-9 
  • Wouters H, Van Dijk L, Van Geffen EC, Gardarsdottir H, Stiggelbout AM, Bouvy ML. Primary-care patients' trade-off preferences with regard to antidepressants.  Psychol Med. 2014 Jan 7:1-8. [Epub ahead of print]  
  • Wouters H, Bouvy ML, Van Geffen EC, Gardarsdottir H, Stiggelbout AM, Van Dijk  L. Antidepressants in primary care: patients' experiences, perceptions, self-efficacy beliefs, and nonadherence. Patient Prefer Adherence. 2014; 8:179-90 



Leids Universitair Medisch Centrum
Gebouw 1
Kamer J10-81

Albinusdreef 2
2333 ZA Leiden
Tel: 071 5264575

Postzone J10-S
Postbus 9600
2300 RC Leiden

E-mail: a.m.stiggelbout@lumc.nl