Participating Bioinformaticians

Dr. Jelle Goeman

Coordinator of the Bioinformatics Center of Expertise

• Gene expression data analysis
• Gene set testing
• Multiple testing
• Prognostic models

Dr. Scott Marshall

• Knowledge sharing for life scientists
• Semantic Web
• Computational Biology
• Data integration
• Information retrieval

Drs. Ramin Monajemi

Scientific Programmer Bioinformatics

Dr. Judith Boer

Assistant professor at the Center for Human and Clinical Genetics

• Experimental design of microarray experiments
• Analysis of expression microarray data
• Integration of multiple sources of high-dimensional genomics data

Peter-Bram 't Hoen, Ph.D.

senior researcher Department of Human Genetics

• -transcriptomics
• -microarrays
• -high-throughput sequencing
• -literature-assisted data analysis and interpretation
• -biomarkers in muscle diseases

Dr. Jan Bert van Klinken

Scientific Researcher Human Genetics

• mathematical modelling
• deterministic/stochastic simulation
• stoichiometric analysis (identification of pathways and conserved moieties)
• steady state analysis, (metabolic) control analysis

Dr. Barend Mons

Marco Roos (PhD)

• e-Science(workflow, semantic web, e-laboratories)
• Hypothesis generation support based on text-mining
• Bioinformatics
• Molecular Cytology

Dr. Peter Taschner

• Human Genome Variation nomenclature
• Locus-specific mutation databases
• Primer design
• Data mining using the internet

Prof.Dr. Sasha Gorbalenya

LUF Professor of Applied Bioinformatics in Virology

• Comparative sequence analysis
• Virus phylogeny
• Structure-function analysis

Igor Sidorov, Ph.D.

Mathematical modeling, algorithms, programming, data management

Dr. Stefan Böhringer

Dr. Bas Heijmans

Dr. Jeanine Houwing

Prof. dr. Joost N. Kok

• Algoritmen
• Data Management
• Data Mining
• Software Technologie

Statistical methods for high-dimensional bioinformatics

Statistical methods for high-dimensional bioinformatics

• Proteomics and metabon(l)omics
• Mass spectrometry, NMR and NIR spectra
• Spectral modeling
• Peak identification
• Spectral pre-processing
• Diagnostic and prognostic models

Dr. Kai Ye

• INDEL (insertions and deletions) detection algorithm - Pindel (www.ebi.ac.uk/~kye/pindel)
• Large scale data mining and sequence analysis: protein, DNA
• Pharmacology modeling: mathematical modeling of receptor-receptor, receptor-ligand interaction
• Homology modeling, MD simulation and docking

Dr. Erik van Zwet

assistant professor, medical statistics

• statistics
• data analysis

Dr. Frank Faas

• Electron microscopy
• Image processing
• Automated data collection, aquisition and analysis
• Software development

Prof. dr. Bram Koster

• Electron microscopy
• 3D electron microscopy
• Cryo electron microscopy

Dr. Raimond Ravelli

Molecular Cell Biology, section Electron Microscopy

• X-ray structure determination
• Macromolecular structure analysis
• Electron microscopy
• Image processing
• Automated data collection and analysis

Ing. Willem Sloos

• microscopic image acquisition
• image processing and data analysis

Dr. Ir. Hans Vrolijk

• microscopic image acquisition
• image processing and data analysis

Dr. Yuri van der Burgt

Assistant Professor

• Clinical peptide- and protein profiling
• Mass spectrometry-based (clinical) proteomics
• Evaluation of MS/MS-data

Assistant Professor

• Proteomics experiment design
• Mass spectrometry data analysis

Ing. Ronald van Eijk

• Pipetting Robotics
• Excel Access based solutions
• Textmining
• Databasing and LIMS development
• Sanger Sequencing

Dr. Jan Oosting

• array analysis
• - SNP (genotyping, copy number analysis
• - Expression
• Pathway analysis