Participating Bioinformaticians

Dr. Jelle Goeman

Coordinator of the Bioinformatics Center of Expertise

• Gene expression data analysis
• Gene set testing
• Multiple testing
• Prognostic models

Dr. Szymon Kielbasa

Drs. Ramin Monajemi

Scientific Programmer Bioinformatics

Dr. Peter-Bram 't Hoen

Universitair Docent, hoofd Human Genetics Bioinformatics Research Group

• high-throughput sequencing
• expression profiling
• transcriptomics
• microarrays
• gebruik van biomedische literatuur voor analyse en interpretatie van high-throughput datasets
• biomarkers in spierziekten

Dr. Jan Bert van Klinken

Scientific Researcher Human Genetics

• mathematical modelling
• deterministic/stochastic simulation
• stoichiometric analysis (identification of pathways and conserved moieties)
• steady state analysis, (metabolic) control analysis

Dr. Jeroen F. J.  Laros

Head of bioinformatics at the LGTC.

• High throughput sequencing
• Human Genome Variation nomenclature
• Algorithms / Programming
• Computer networks / Operating systems
• Locus specific databases

Dr. Barend Mons

Dr. Marco Roos

• e-Science (workflow, semantic web, e-laboratories)
• Hypothese ondersteuning gebaseerd op text-mining
• Bioinformatica
• Moleculaire Cytologie

Dr. Peter Taschner

• Human Genome Variation nomenclature
• Locus-specific mutation databases
• Primer design
• Data mining using the internet

Prof.Dr. Sasha Gorbalenya

LUF Professor of Applied Bioinformatics in Virology

• Comparative sequence analysis
• Virus phylogeny
• Structure-function analysis

Igor Sidorov, Ph.D.

Mathematical modeling, algorithms, programming, data management

Dr. Stefan Böhringer

• Statistical genetics
• Genome wide association analysis
• High-dimensional traits
• Heritability analysis
• Haplotype analysis
• Population Genetics
• Population stratification
• Programming languages and computational problems
• Databases and analysis pipelines

Dr. B.T. (Bas) Heijmans

Dr. Jeanine Houwing

Prof. dr. Joost N. Kok

• Algoritmen
• Data Management
• Data Mining
• Software Technologie

Dr. Scott Marshall

• Knowledge sharing for life scientists
• Semantic Web
• Computational Biology
• Data integration
• Information retrieval

Dr. Bart Mertens

Statistical methods for high-dimensional bioinformatics

• Proteomics and metabon(l)omics
• Mass spectrometry, NMR and NIR spectra
• Spectral modeling
• Peak identification
• Spectral pre-processing
• Diagnostic and prognostic models

Dr. Kai Ye

• INDEL (insertions and deletions) detection algorithm - Pindel (www.ebi.ac.uk/~kye/pindel)
• Large scale data mining and sequence analysis: protein, DNA
• Pharmacology modeling: mathematical modeling of receptor-receptor, receptor-ligand interaction
• Homology modeling, MD simulation and docking

Dr. Erik van Zwet

assistant professor, medical statistics

• statistics
• data analysis

Dr. Frank Faas

• Electron microscopy
• Image processing
• Automated data collection, aquisition and analysis
• Software development

Prof. dr. Bram Koster

• Electron microscopy
• 3D electron microscopy
• Cryo electron microscopy

Dr. Raimond Ravelli

Molecular Cell Biology, section Electron Microscopy

• X-ray structure determination
• Macromolecular structure analysis
• Electron microscopy
• Image processing
• Automated data collection and analysis

Ing. Willem Sloos

• microscopic image acquisition
• image processing and data analysis

Dr. Ir. Hans Vrolijk

• microscopic image acquisition
• image processing and data analysis

Dr. Yuri van der Burgt

Assistant Professor

• Clinical peptide- and protein profiling
• Mass spectrometry-based (clinical) proteomics
• Evaluation of MS/MS-data

Dr. Alex Henneman

• Mass spectrometry data processing and analysis
• Processing and analysis allgorithm development
• Physics, mathematics and statistics.
• High performance computing
• Analysis, processing and storage infrastructure design

Dr. Magnus Palmblad

• Proteomics experiment design
• Mass spectrometry data analysis

Ing. Ronald van Eijk

• Pipetting Robotics
• Excel Access based solutions
• Textmining
• Databasing and LIMS development
• Sanger Sequencing

Dr. Jan Oosting

• array analyse
• - SNP (genotypering, numerieke afwijkingen)
• - Expressie
• Pathway analyse