J.V.M.G. Bovée MD,PhD

Positions

- Work package leader in the Eurobonet Network of Excellence WP1.1 "Biology of central and peripheral chondrosarcoma"
- Board member of the European MusculoSkeletal Oncology Society
- Board member of the dutch working group for molecular diagnostics in pathology
- Member Netherlands Committee on Bone Tumours
- Member of scientific advisory board of Dutch Multiple Osteochondromas patient organization
- Senior editor International Journal of Clinical and Experimental Pathology

Projects

1. "Estrogen signalling as a target for chondrosarcoma treatment" KWF UL 2007-3815 Projectleaders: Bovée JVMG, Karperien M, Hogendoorn PCW.
2. "Bridging the gap between normal and neoplastic cartilage regulation" ZON-MW / Netherlands Organization for Scientific Research. VIDI-programma 2006 en Aspasia.  Projectleader: Bovée JVMG
3. "Primary vascular tumours of bone; towards a new classification based on pathology and genetics". Verbeke SLJ. Koningin Wilhelmina Fonds / Dutch Cancer Society 2006. Projectleaders: Bovée JVMG, Hogendoorn PCW
4. Participation in EuroBoNet consortium (www.eurobonet.eu). Sixth Framework, Networks of Excellence, "Uncommon Cancers in Adults and Children" work-package leader WP1.1 "Biology of central and peripheral chondrosarcoma" 2006.
5. "Expression profiling of peripheral chondrosarcoma progression: towards molecular understanding for diagnostic tools." Koningin Wilhelmina Fonds / Dutch Cancer Society 2002.
   Projectleaders : Hogendoorn PCW, Bovée JVMG, Cleton-Jansen AM.
6. "Characterization of the pathways in the evolvement of central chondrosarcoma of bone." ZON-MW / Netherlands Organization for Scientific Research 2002. Projectleader : Bovée JVMG.
7. "Novel surface markers in tumors of cartilaginous origin. Evaluation of their diagnostic value. A collaborative study. " Schweizerische Krebs Liga Krebsforschung Schweiz / Swiss Cancer Foundation 2002. Projectleaders : Mainil-Varlet P (Institute of Pathology, University of Bern, Switzerland), Bovée JVMG, Hogendoorn PCW.

Selected publications

1. Bovée JVMG. EXTra hit for mouse osteochondroma. Proc Natl Acad Science USA 2010: 107(5):1813-1814
2. Schrage,Y.M., Briaire-de Bruijn,I.H., de Miranda,N.F.C.C., van Oosterwijk,J., Taminiau,A.H.M., van Wezel,T., Hogendoorn,P.C.W., and Bovée JVMG. Kinome profiling of chondrosarcoma reveals Src-pathway activity and dasatinib as option for treatment. Cancer Res 2009: 69(15):6216-22
3. Gelderblom H, Hogendoorn PCW, Dijkstra SD, van Rijswijk CS, Krol AD, Taminiau AHM, Bovée JVMG. The clinical approach towards chondrosarcoma.      Oncologist. 2008; 13(3):320-9.
4. Bovée JVMG, Cleton-Jansen AM, Taminiau AHM and Hogendoorn PCW. Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment.  Lancet Oncol 2005; 6: 599–607
5. Bovée JVMG, Cleton-Jansen AM, Wuyts W, Caethoven G, Taminiau AHM, Bakker E, Van Hul W, Cornelisse CJ, Hogendoorn PCW. EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas. Am J Hum Genet 1999; 65: 689-98.