Hans Tanke

CURRICULUM VITAE

Name: Hans J. Tanke; born 26-02-1952
Position: Head,  Department of Molecular Cell Biology
Leiden University Medical Center
Einthovenweg 20 Bldg 2. PO Box 9600
2300 RC Leiden; The Netherlands
Email: h.j.tanke@lumc.nl
Website: www.lumc.nl/con/1050/  

• 1977 Doctoral Degree in  Biochemistry, Utrecht University (with Immunology and Clinical Chemistry)
• 1977 Start PhD study Leiden University
• 1978 Three months training at Lawrence Livermore Laboratories; Livermore CA, USA
• 1982 PhD, University of Leiden, The Netherlands Cytochemical and Cytometric Methods for DNA and RNA analysis (Promotor: P. van Duijn, J.S. Ploem)

Post doctoral training:

• 1982 -1988 Laboratory of Cytochemistry and Cytometry, Leiden
• 1982 Department of Pathology, Innsbruck (2 months).
• 1987 -1994 Part time Consultant at the Hochschule Hannover; Germany

Professional experience:

• 1988 - 1993 Associate Professor;  University of Leiden
• 1990 Visiting Professor; University of Bologna and Urbino; Italy
• 1991 - 1997 Visiting Professor at VUB Brussels
• 1993-present Professor of Cell Biology (Analytical Cytology)
• 1997-present Chairman Department of Molecular Cell Biology
• 1998-present Member of the board research of division 5 of the LUMC

Honors and awards:

• 1982 International "C.E. Alken-Preis" for urological Research
• 1987 "Bisschof-Preis, German  Urology" (as co-author).
• 1989 PIONIER grant; NWO; the  Netherlands
• 2008 Membership services award International Society for Advanced Cytometry

Memberships:

• Member Council International Society for Analytical Cytology (two terms)
• Member Council Society for Analytical Cellular Pathology (one term)

Editorial boards:

• Cytometry (until 2006)
• Journal of Microscopy (until 2005)
• Protocols in cytometry (until 2005)
• Bioanalytical reviews (recently founded)
• Cellular Oncology (ongoing)

Scientific advisory boards and consultancy:

• VYSIS-USA: member SAB until 2002
• Kreatech Biotechnology (Amsterdam-NL): Chairman SAB until present
• Leica Microsystems (Wetzlar-Germany): member of supervisory board 1999-2005
• Consultant for Applied Imaging (San Jose CA/Newcastle UK), Orasure (Bethlehem-PA), PerkinElmer (USA)
• Boehringer-Roche (Germany) 

Teaching:

• Undergraduate: Introduction Microscopy, Functional Morphology
• Postgraduate: “Advanced microscopy”, “Medical imaging”

Theses:

Supervision as promotor of 25 PhD students; member of thesis examination committees in more than 40 occasions (national; Leiden, Delft, Amsterdam, Enschede) and 2 (international: Finland and Denmark)

Research fields:

His present research field relates to the development of novel fluorescence based technology including advanced imaging to study the molecular composition of cells and chromosome. A special research focus is the analysis of molecular interactions in living cells using CSLM, FRAP and FRET-FLIM techniques. Aim is to unravel the molecular mechanisms that determine normal and abnormal cell function, aiming to understand the cause of inherited and acquired disease. He pioneered the development of novel fluorescent reporters and promoted the use of digital fluorescence microscopy for this purpose, one of the first Dutch programs awarded with a NWO Pioneer grant in 1989. In past decades his team has made many original contributions to the field of FISH and immunocytochemistry and automated microscopy. Since three years his team develops technology for point-of-care diagnosis of infectious diseases using saliva. Hans Tanke  is (co)-author of more than 300 scientific papers, and is (co)-inventor on 5 patents (see below).

The Department of Molecular Cell Biology that he chairs since 1997 has four main research programs: “Signal transduction in aging related diseases (cancer, diabetes, osteoporosis)”, “Gene regulation and cell differentiation (including gene therapy and stem cell research)”, “Neurosciences in Drosophila and rodents: from genes to neuronal networks” and “Microscopic imaging and technology” (see also www.lumc.nl/con/1050/).

 

 

 

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Vakgebied(en):

• Professor
• Cell growth and Transcription regulation