Student research projects

Possibilities

There are frequent opportunities for students to do shorter or longer research projects or traineeships within the LUMC Biomolecular Mass Spectrometry Unit. Students with a strong general background in the natural sciences and pursuing an education or career in biomedical sciences, molecular biology, analytical chemistry, bioinformatics or physics are particularly encouraged to contact us. Actual information about projects and possibilities can be found on the  Leiden University Blackboard, by contacting Professor André M. Deelder or for specific enquiries Dr. Y. v.d. Burgt, (Mass spectrometry-based clinical proteomics),  Dr. L. McDonnell, (Imaging mass spectrometry), Dr. P. Hensbergen, (Cell Biology Proteomics), Dr. O. Mayboroda, (Advanced separations and clinical MS-metabolomics), Dr. A. Meissner, (Biomedical NMR spectroscopy), Dr. M. Palmblad, (FTICR- and high-throughput proteomics), Dr. A. van Remoortere, (Biomolecular interaction analysis), Dr. Manfred Wuhrer, (Glycomics and proteomics).
 

Former/current student research projects

Pieter Kooijman, VU Amsterdam
May 2012 - August 2012
ultra low flow direct infusion analysis

Rudmer Postma, Leiden University
April 2012 – October 2012
NMR-based metabolomic analysis of cerebrospinal fluid in migraine

Wendy Plugge, Hogeschool Leiden
Dec 2011 - April 2012
Expansion of Taverna Workflows for Data Analysis in Proteomics

Hulda Jónasdóttir, VU Amsterdam
Sept 2011 - April 2012
Non-aqueous CE and CESI MS for Lipid analysis

Ksenia Yashina and Boris Nagaev, Moscow State University
July 2011 - August 2011
Integration of MS-GFDB in peptide/protein identification workflows

Marie Ciret, University of Poitiers
June 2011 - Aug 2011
Algorithms for constructing and searching peptide spectral libraries in proteomics

Khalid Ahmed, Hogeschool Leiden
April 2011 - June 2011
New sample preparation method for proteome analysis

Amir Dadashzadeh, Hogeschool Leiden
May 2011 - August 2011
Additives for enhancing negative electrospray in metabolomics research

Kevin van der Graaf, Hogeschool Leiden
May 2011 - July 2011
Methods for the proteolytic cleavage of immunoglobulins

Nienke Derks, Leiden University
March 2011- June 2011
Detection of CSF peptide changes during the progression of Alzheimer’s disease

Antoinette van Ouwerkerk, Leiden University.
Jan 2011-July 2011
Analysis of the diagnostic potential of immunoglobuline glycosylation in Lyme Disease

Kay Schallert,University of Magdeburg
Jan 2011-July 2011
Development of a workflow for in-depth, quantitative phosphoproteomics

Maja Pucic, University of Zagreb, Croatia
Nov 2010 - Jan 2010
The variability of IgG glycosylation in a Croatian population study

Daan Luining, Hogeschool Leiden
Oct 2010-June 2011
Development of new measurement strategies that enable a rigorous quantitative comparison of multiple patient samples by using isotopically labeled peptides as internal standards.

Ruben Curfs, Leiden University
Oct 2010-March 2011
Glycan microarray analysis of anti-carbo-hydrate autoantibody responses in colorectal cancer

Marcus Hoffmann, Max Planck Institute Magdeburg
Sept 2010-March 2011
Tandem Mass Spectrometry of Glycopeptides

Artem Artemov, Moscow State University
Aug 2010–May 2011
Cross-platform analysis of biomarkers and clinical predictors in Urinary Tract Infections 

Vladimir Arzhanik and Daria Shalaeva, Moscow State University
Juli 2010-Aug 2010
Workflows for Peptide Identification by Tandem Mass Spectrometry

Bjorn Victor,  Institute of Tropical Medicin in Antwerpen
Juni 2010-Nov 2011
Molecular Characterization of Excretion-Secretion Products of the Parasite Taenia solium

Alegria Carrasco Pancorbo, University of Granada
Juni 2010–Okt 2010
MS profiling of olive’s oil polyphenols in human urine

Nico van den Oever and Georgi Kanev, Hogeschool Leiden
May 2010-June 2010
MALDI imaging mass spectrometry: toward high mass proteins

Kathrin Stavenhagen, Beuth Hochschule fuer Technik Berlin
March 2010-August 2010
Glycomics of cancer tissues

Lisette Cornelissen, LUMC
March 2010-June 2010
Regulated patterns of IgG Fc and Fab glycosylation in murine schistosomiasis

Matthias Borowiak, University of Magdeburg
March 2010-June 2010
Cancer-induced changes in the total plasma N-glycome

Erik Blok , LUMC
March 2010-June2010
Natural glycan arrays for analysis autoantibodies in cancer

Mahdi Hemayatkar, Pasteur Institute of Iran, Tehran
February 2010-July 2010
Glycosylation analysis of recombinantly expressed proteins and human plasma proteins

Arne vd Meer, VU
Jan 2010– Sept 2010
Evaluation of a new API source and appliction of the source for the analysis of samples of biological origin

Erica Gianazza, University of Milano-Bicocca
Jan 2010 -Dec 2010
Biomarker research for renal cell carcinoma

Miguel García, Escuela Politécnica Nacional (Ecuador), bachelor
October 2009-August 2010
Taenia solium proteomics using ion trap and ultrahigh-resolution time-of-flight mass spectrometry

Elizabeth Minda, Universidad Central del Ecuador
October 2009-March 2010
Proteomics and molecular diagnostics of Taenia solium

Gillian Lee Hertlein,VU Amsterdam
June-September 2009
Novel tools for mitochondrial proteomics of cells carrying a mitochondrial DNA mutation 

Anfisa Popova and Kirill Prusov, Moscow State University
June-July 2009
Peptide Identification by Tandem Mass Spectrometry

Nico de Velde, Hogeschool Leiden
April-June 2009
Imaging lipids using Fourier transform ion cyclotron resonance mass spectrometry

Ivar Lugtenburg and Youri Hoogstrate, Hogeschool Leiden
April-July 2009
Retention time prediction of amino acid sequences

René Hennig, University of Magdeburg
March-October 2009
Development of a sample preparation method for APTS-labeled N-glycans using HILIC-SPE.

Sanne de Jong, LUMC
March 2009-June 2009
The role of antibody glycosylation in humoral responses to inflenza and tetanus vaccination

Jeroen Paardekooper Overman, VU Amsterdam
January-May 2009
Quantitative proteomic analysis of mitochondria from cells carrying a disease causing tRNA mutation

Evelyne Steenvoorden, Hogeschool Leiden
October 2008-September 2009
A high throughput method for glycan analysis of specific proteins

Lily David, Hogeschool Leiden
October 2008
Evaluation of a new type of solid-phase extraction micropipette tips

Bo Blanckenburg, TU Delft, master
October 2008-August 2009
Direct Infusion Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Rapid Screening of Body Fluids

Dick-Paul Kloos, VU Amsterdam
September 2008-July 2009     
Miniaturization of the sample preparation workflow for peptidomics

Lily David, Gert-Jan den Heijer and Wai Yi Leung, Hogeschool Leiden
September 2008-January 2009
Comparative Gene and Protein Expression Analysis

Olga Gancharova and Mikhail Kuravskiy, Moscow State University
June-August 2008
Visualization of Comparative mRNA and Protein Expression Analysis

Kawita Kanhai (LUMC)
maart 2008-september 2008
Peptide- and protein profiling in body fluids using mass spectrometry-based clinical proteomics