Publications

Core publications in glycobiology

Changes in antigen-specific IgG1 Fc N-glycosylation upon influenza and tetanus vaccination.
Selman MH, de Jong SE, Soonawala D, Kroon FP, Adegnika AA, Deelder AM, Hokke CH, Yazdanbakhsh M, Wuhrer M.
Mol Cell Proteomics 2011, Dec. 19

Schistosoma mansoni egg glycoproteins and C-type lectins of host immune cells: Molecular partners that shape immune responses.
Meevissen MH, Yazdanbakhsh M, Hokke CH.
Exp Parasitol. 2011 May 15.

Targeted glycoproteomic analysis reveals that kappa-5 is a major, uniquely glycosylated component of Schistosoma mansoni egg antigens.
Meevissen MH, Balog CI, Koeleman CA, Doenhoff MJ, Schramm G, Haas H, Deelder AM, Wuhrer M, Hokke CH.
Mol Cell Proteomics. 2011 10(5).

The proteome of the insoluble Schistosoma mansoni eggshell skeleton.
Dewalick S, Bexkens ML, van Balkom BW, Wu YP, Smit CH, Hokke CH, de Groot PG, Heck AJ, Tielens AG, van Hellemond JJ.
Int J Parasitol. 2011 Apr; 41(5):523-32.

Ligand identification of carbohydrate-binding proteins employing a biotinylated glycan binding assay and tandem mass spectrometry.
Wuhrer M, van Remoortere A, Balog CI, Deelder AM, Hokke CH.
Anal Biochem. 2010 Nov 15;406(2):132-40.

Helminths and dendritic cells: sensing and regulating via pattern recognition receptors, Th2 and Treg responses.
Everts B, Smits HH, Hokke CH, Yazdanbakhsh M.
Eur J Immunol. 2010 Jun;40(6):1525-37.

Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function.
Eggink D, Melchers M, Wuhrer M, van Montfort T, Dey AK, Naaijkens BA, David KB, Le Douce V, Deelder AM, Kang K, Olson WC, Berkhout B, Hokke CH, Moore JP, Sanders RW.
Virology. 2010 Jun 5;401(2):236-47.

Structural Characterization of Glycans on Omega-1, a Major Schistosoma mansoni Egg Glycoprotein That Drives Th2 Responses.
Meevissen MH, Wuhrer M, Doenhoff MJ, Schramm G, Haas H, Deelder AM, Hokke CH.
J Proteome Res. 2010 May 7;9(5):2630-42.

Mass spectrometric identification of aberrantly glycosylated human apolipoprotein C-III peptides in urine from Schistosoma mansoni-infected individuals. Balog CI, Mayboroda OM, Wuhrer M, Hokke CH, Deelder AM, Hensbergen PJ. Mol Cell Proteomics. 2010 Apr;9(4):667-81.

Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses. Everts B, Perona-Wright G, Smits HH, Hokke CH, van der Ham AJ, Fitzsimmons CM, Doenhoff MJ, van der Bosch J, Mohrs K, Haas H, Mohrs M, Yazdanbakhsh M, Schramm G. J Exp Med. 2009 Aug 3;206(8):1673-80.

Glycotope analysis in miracidia and primary sporocysts of Schistosoma mansoni: differential expression during the miracidium-to-sporocyst transformation. Peterson NA, Hokke CH, Deelder AM, Yoshino TP. Int J Parasitol. 2009 Oct;39(12):1331-44.

Molecular characterisation of kappa-5, a major antigenic glycoprotein from Schistosoma mansoni eggs. Schramm G, Hamilton JV, Balog CI, Wuhrer M, Gronow A, Beckmann S, Wippersteg V, Grevelding CG, Goldmann T, Weber E, Brattig NW, Deelder AM, Dunne DW, Hokke CH, Haas H, Doenhoff MJ. Mol Biochem Parasitol. 2009 Jul;166(1):4-14.

Characterization of a diagnostic Fab fragment binding trimeric Lewis X. de Geus DC, van Roon AM, Thomassen EA, Hokke CH, Deelder AM, Abrahams JP. Proteins. 2009 Aug 1;76(2):439-47.

Molecular and functional characterization of a tandem-repeat galectin from the freshwater snail Biomphalaria glabrata, intermediate host of the human blood fluke Schistosoma mansoni. Yoshino TP, Dinguirard N, Kunert J, Hokke CH. Gene. 2008 Mar 31;411(1-2):46-58.

Serum antibody screening by surface plasmon resonance using a natural glycan microarray. de Boer AR, Hokke CH, Deelder AM, Wuhrer M. Glycoconj J. 2008 Jan;25(1):75-84.

Mass spectrometric detection of urinary oligosaccharides as markers of Schistosoma mansoni infection. Robijn ML, Planken J, Kornelis D, Hokke CH, Deelder AM. Trans R Soc Trop Med Hyg. 2008 Jan;102(1):79-83.

General microarray technique for immobilization and screening of natural glycans. de Boer AR, Hokke CH, Deelder AM, Wuhrer M. Anal Chem. 2007 Nov 1;79(21):8107-13.

Glycomics-driven discoveries in schistosome research. Hokke CH, Deelder AM, Hoffmann KF, Wuhrer M. Exp Parasitol. 2007 Nov;117(3):275-83.. Review.

Integrating transcriptome, proteome and glycome analyses of Schistosoma biology. Hokke CH, Fitzpatrick JM, Hoffmann KF. Trends Parasitol. 2007 Apr;23(4):165-74. Review.

Targeted identification of a unique glycan epitope of Schistosoma mansoni egg antigens using a diagnostic antibody. Robijn ML, Koeleman CA, Wuhrer M, Royle L, Geyer R, Dwek RA, Rudd PM, Deelder AM, Hokke CH. Mol Biochem Parasitol. 2007 Feb;151(2):148-61

Schistosoma mansoni eggs excrete specific free oligosaccharides that are detectable in the urine of the human host. Robijn ML, Koeleman CA, Hokke CH, Deelder AM. Mol Biochem Parasitol. 2007 Feb;151(2):162-72. 

Efficient introduction of a bisecting GlcNAc residue in tobacco N-glycans by expression of the gene encoding human N-acetylglucosaminyltransferase III. Rouwendal GJ, Wuhrer M, Florack DE, Koeleman CA, Deelder AM, Bakker H, Stoopen GM, van Die I, Helsper JP, Hokke CH, Bosch D.

The host's genetic background determines the extent of angiogenesis induced by schistosome egg antigens. Van de Vijver KK, Colpaert CG, Jacobs W, Kuypers K, Hokke CH, Deelder AM, Van Marck EA. Acta Trop. 2006 Oct;99(2-3):243-51.

Gender-specific expression of complex-type N-glycans in schistosomes. Wuhrer M, Koeleman CA, Fitzpatrick JM, Hoffmann KF, Deelder AM, Hokke CH. Glycobiology. 2006 Oct;16(10):991-1006.

IPSE/alpha-1, a major secretory glycoprotein antigen from schistosome eggs, expresses the Lewis X motif on core-difucosylated N-glycans. Wuhrer M, Balog CI, Catalina MI, Jones FM, Schramm G, Haas H, Doenhoff MJ, Dunne DW, Deelder AM, Hokke CH. FEBS J. 2006 May;273(10):2276-92.

Repeats of LacdiNAc and fucosylated LacdiNAc on N-glycans of the human parasite Schistosoma mansoni. Wuhrer M, Koeleman CA, Deelder AM, Hokke CH. FEBS J. 2006 Jan;273(2):347-61.

LacdiNAc- and LacNAc-containing glycans induce granulomas in an in vivo model for schistosome egg-induced hepatic granuloma formation. Van de Vijver KK, Deelder AM, Jacobs W, Van Marck EA, Hokke CH. Glycobiology. 2006 Mar;16(3):237-43.  

Collaborative glycomics publications

Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health.
Ruhaak LR, Uh HW, Beekman M, Hokke CH, Westendorp RG, Houwing-Duistermaat JJ, Wuhrer M, Deelder AM, Slagboom PE.
J Proteome Res. 2011 Apr 1;10(4):1667-74.

Decreased levels of bisecting GlcNAc glycoforms of IgG are associated with human longevity.
Ruhaak LR, Uh HW, Beekman M, Koeleman CA, Hokke CH, Westendorp RG, Wuhrer M, Houwing-Duistermaat JJ, Slagboom PE, Deelder AM.
PLoS One. 2010 Sep 7;5(9):e12566.

Golgi targeting of Drosophila melanogaster beta4GalNAcTB requires a DHHC protein family-related protein as a pilot. Johswich A, Kraft B, Wuhrer M, Berger M, Deelder AM, Hokke CH, Gerardy-Schahn R, Bakker H. J Cell Biol. 2009 Jan 12;184(1):173-83.

Hydrophilic interaction chromatography-based high-throughput sample preparation method for N-glycan analysis from total human plasma glycoproteins. Ruhaak LR, Huhn C, Waterreus WJ, de Boer AR, Neusüss C, Hokke CH, Deelder AM, Wuhrer M. Anal Chem. 2008 Aug 1;80(15):6119-26.

Glycosylation profiling of immunoglobulin G (IgG) subclasses from human serum. Wuhrer M, Stam JC, van de Geijn FE, Koeleman CA, Verrips CT, Dolhain RJ, Hokke CH, Deelder AM. Proteomics. 2007 Nov;7(22):4070-81.

Distinct contributions of beta 4GalNAcTA and beta 4GalNAcTB to Drosophila glycosphingolipid biosynthesis. Stolz A, Haines N, Pich A, Irvine KD, Hokke CH, Deelder AM, Gerardy-Schahn R, Wuhrer M, Bakker H. Glycoconj J. 2008 Feb;25(2):167-75.

Rouwendal GJ, Wuhrer M, Florack DE, Koeleman CA, Deelder AM, Bakker H, Stoopen GM, van Die I, Helsper JP, Hokke CH, Bosch D. Glycobiology. 2007 Mar;17(3):334-44. Glycobiology. 2007 Mar;17(3):334-44.

Glycoproteomics based on tandem mass spectrometry of glycopeptides. Wuhrer M, Catalina MI, Deelder AM, Hokke CH. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Apr 15;849(1-2):115-28. Review.

Mass spectrometry of proton adducts of fucosylated N-glycans: fucose transfer between antennae gives rise to misleading fragments. Wuhrer M, Koeleman CA, Hokke CH, Deelder AM. Rapid Commun Mass Spectrom. 2006;20(11):1747-54.

Oligosaccharide analysis by capillary-scale high-pH anion-exchange chromatography with on-line ion-trap mass spectrometry. Bruggink C, Wuhrer M, Koeleman CA, Barreto V, Liu Y, Pohl C, Ingendoh A, Hokke CH, Deelder AM. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Dec 27;829(1-2):136-43.