2007 - 2008

•  Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity.Lasonder E, Janse CJ, van Gemert GJ, Mair GR, Vermunt AM, Douradinha BG, van Noort V, Huynen MA, Luty AJ, Kroeze H, Khan SM, Sauerwein RW, Waters AP, Mann M, Stunnenberg HG. PLoS Pathog. 2008,4:e1000195.
•  Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes. van Schaijk BC, Janse CJ, van Gemert GJ, van Dijk MR, Gego A, Franetich JF, van de Vegte-Bolmer M, Yalaoui S, Silvie O, Hoffman SL, Waters AP, Mazier D, Sauerwein RW, Khan SM. PLoS ONE. 2008,3:e3549.
•  Analysis of mutant Plasmodium berghei parasites lacking expression of multiple PbCCp genes. Lavazec C, Moreira CK, Mair GR, Waters AP, Janse CJ, Templeton TJ. Mol Biochem Parasitol. 2008 Sep 19.
•  Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites. Franke-Fayard B, Djokovic D, Dooren MW, Ramesar J, Waters AP, Falade MO, Kranendonk M, Martinelli A, Cravo P, Janse CJ. Int J Parasitol. 2008, 38:1651-62.
•  Plasmodium lipid rafts contain proteins implicated in vesicular trafficking and signalling as well as members of the PIR superfamily, potentially implicated in host immune system interactions. Di Girolamo F, Raggi C, Birago C, Pizzi E, Lalle M, Picci L, Pace T, Bachi A, de Jong J, Janse CJ, Waters AP, Sargiacomo M, Ponzi M. Proteomics. 2008, 8:2500-13.
•  The malaria secretome: from algorithms to essential function in blood stage infection. van Ooij C, Tamez P, Bhattacharjee S, Hiller NL, Harrison T, Liolios K, Kooij T, Ramesar J, Balu B, Adams J, Waters A, Janse C, Haldar K. PLoS Pathog. 2008 13,4:e1000084.
•  The Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites. Moreira CK, Templeton TJ, Lavazec C, Hayward RE, Hobbs CV, Kroeze H, Janse CJ, Waters AP, Sinnis P, Coppi A. Cell Microbiol. 2008, 10:1505-16.
•  A conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes. Braks JA, Mair GR, Franke-Fayard B, Janse CJ, Waters AP. Nucleic Acids Res. 2008, 36:1176-86.
•  The exoneme helps malaria parasites to break out of blood cells. Janse CJ, Waters AP.  Cell. 2007 131:1036-8.
•  Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection. Douradinha B, van Dijk MR, Ataide R, van Gemert GJ, Thompson J, Franetich JF, Mazier D, Luty AJ, Sauerwein R, Janse CJ, Waters AP, Mota MM. Int J Parasitol. 2007, 37:1511-9.
•  A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria. Amante FH, Stanley AC, Randall LM, Zhou Y, Haque A, McSweeney K, Waters AP, Janse CJ, Good MF, Hill GR, Engwerda CR. Am J Pathol. 2007, 171:548-59.
•  Plasmodium cysteine repeat modular proteins 1-4: complex proteins with roles throughout the malaria parasite life cycle.Thompson J, Fernandez-Reyes D, Sharling L, Moore SG, Eling WM, Kyes SA, Newbold CI, Kafatos FC, Janse CJ, Waters AP. Cell Microbiol. 2007, 9:1466-80.
•  Functional characterization of the Plasmodium falciparum and P. berghei homologues of macrophage migration inhibitory factor. Augustijn KD, Kleemann R, Thompson J, Kooistra T, Crawford CE, Reece SE, Pain A, Siebum AH, Janse CJ, Waters AP.  Infect Immun. 2007, 75:1116-28.
•  The use of transgenic Plasmodium berghei expressing the Plasmodium vivax antigen P25 to determine the transmission-blocking activity of sera from malaria vaccine trials. Ramjanee S, Robertson JS, Franke-Fayard B, Sinha R, Waters AP, Janse CJ, Wu Y, Blagborough AM, Saul A, Sinden RE. Vaccine. 2007, 25:886-94.