Leiden Malaria Research Group (LMRG)

General information on malaria: in Dutch
(Algemene informatie over malaria)

Head of the group:
Dr. Chris J. Janse
Principal investigators:
Dr. B. Franke-Fayard
Dr. S.M. Khan

Main research themes:

• Identification and analysis of parasite proteins that are (putative) targets for drugs and vaccines
• Development of a malaria vaccine based on genetically attenuated parasites
• Analysis of parasite-host interactions involved in pathology and disease

We use a malaria parasite of rodents,  Plasmodium berghei, as a model for human malaria infections (see research model)

• News about the research
• Research lines and publications
• Protocols and databases, available on a password protected 'SharePoint' environment
• Plasmids for genetic modification and transgenic parasite lines are available from the 'Malaria Research and Reference Reagent Resource Center' ( MR4).

The LMRG provides a database containing information on all genetically modified rodent parasite lines: see  pberghei.eu.